The relationship between FS and FNPA was explored, and a significant trend was noted with FNPA scores in this population; however, a limited range of FS scores may have affected this finding ( β = 0.534, CI 0.126, 0.941; p = .011).
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Neurons with a higher resistance showed a significant trend for shorter and more intense rebounds compared to neurons with a lower resistance (50 ms rebound R 2 = 0.103, P = 0.011; 100 ms rebound R 2 = 0.1503, P = 0.0011; and 250 ms rebound R 2 = 0.048, P = 0.068).
Moreover, we observed a significant trend towards a decline in urine phosphate excretion, visible as early as the third month of treatment (0.53 ± 0.18 vs. 0.44 ± 0.17 g/24 h; p = 0.011).
The log rank analyses ( Figures 1 and 2 ) showed that the RFS and OS were significantly different among the quartiles with a significant trend towards worse survival in more deprived quartiles ( p = 0.012, and 0.011, respectively).
After adjusting for age, sex, smoking status, and use of lipid-lowering and antihypertensive medications, we determined that participants carrying the minor alleles of the rs117685211 genotype exhibited a significant trend of higher levels of Ox-HDL in the additive and dominant models ( p = 0.012 and 0.002, respectively), and conversely showed a significant trend of lower levels of ApoA1 and HDL-P (including L, M, and S-HDL-P; all p values were ≤0.001 in the additive and dominant models).
Similarly, a significant trend was also found between mean age and blood loss in the NE (Omnibus p = 0.012) and CR (Omnibus p = 0.04) groups (Supplementary Figure S21‐22 ). 5 Discussion NE evacuation was initially suggested by Auer et al. and has since developed into a potentially effective surgical technique for managing spontaneous supratentorial ICH due to its high evacuation rate, superior protection of the surrounding brain tissue, and lower complication rates (Ye et al. 2017 ; Zhang et al. 2014 ).
Thus, trend analysis for the presence of AGR across quartiles of activin A demonstrated a significant trend for the odds ratio (OR) of having AGR at 3 months with increasing activin A concentrations ( P = 0.012), identifying a threshold of activin A at the median value (≥0.23 ng/mL, Fig. 2 ).
The heavy chains of mAbs, but not the light chains, showed a significant trend ( P =0.012) to greater divergence from germline with increased time between infection and peripheral blood mononuclear cell (PBMC) collection ( Fig. 8e ).
Familiarity with Nutri-Score increased monotonically across educational strata, from 30.5% in upper-secondary/vocational respondents to 33.3% in post-secondary non-tertiary, 38.7% in university, and 48.4% in postgraduate respondents, with a significant trend across ordered educational levels (Spearman ρ = 0.14, p = 0.012); the omnibus four-group χ 2 did not reach significance (χ 2 = 6.27, df = 3, p = 0.099), consistent with a graded rather than threshold effect.
Importantly, there was a significant trend indicating that as D-dimer levels rose, the risk of mortality also increased ( p for trend, HR 1.15, 95% CI = 1.03 ~ 1.28, p = 0.012).
Results: After adjusting for covariates, a significant trend was found between the dietary iron and elevated fasting glucose ( p = 0.012), whereas no such trend was observed for the rs864745 ( p = 0.932).
Regression analysis shows that there is a significant trend toward increased levels of late apoptosis and total apoptosis with increasing statin concentration (Linear regression: p = 0.012 (r = 0.79) and p = 0.019 (r = 0.75) (late and total apoptosis for lovastatin), p = 0.003 (r = 0.86) and p = 0.044 (r = 0.46) (late and total apoptosis for mevastatin), p = 0.014 (r = 0.77) and p = 0.038 (r = 0.69) (late and total apoptosis for simvastatin)).
Only women delivering at Katoro rural health centre had a significant trend towards increased odds of peripheral malaria by microscopy in both bivariate (OR = 1.72, p = 0.012) and multivariable analysis (AOR = 2.77, p = 0.014).
The distribution of risk categories at initial presentation showed a significant trend towards higher risk in extragonadal GCTs (p=0.013).
Moreover, linear-by-linear association analysis demonstrated a significant trend ( p = 0.013), indicating that higher tumor grade was associated with an increased risk of death within two years. 4.
A significant trend was observed for decrease in body weight ( P = 0.013), BMI ( P = 0.025), and trunk fat mass ( P = 0.020) across quartiles of changes in HbA 1c .
We also discovered a significant trend of shortened survival in patients of Cluster B (HR = 2.132, 95%CI: 1.014–4.484; Renyi test p = 0.013, see Figure 1 G).
There was a significant trend toward increased use of systemic HRT (73.8 % vs. 100 %, p = 0.013), including transdermal HRT (45.2 % vs. 84.2 %, p = 0.004) in the weight gain cohort.
When TyG index was assessed as quartiles, compared with the reference group (Quartile 1), the hazard ratio of stroke was 1.04 in Quartile 2, 1.43 in Quartile 3, and 1.45 in Quartile 4, with a significant trend test ( P = 0.013).
In addition, there was a significant trend for the spatial variability of TTP to increase with age ( R = 0.34, 0.011/year, p = 0.013).
Critically, the fundamental linear dose-response relationship was reaffirmed by a significant trend across quartiles (p = 0.013) and a consistently positive continuous association in both the primary (HR 1.38 per SD) and sensitivity (HR 1.65 per SD) models.
An interesting aside was the observation of a significant trend (p = 0.013) to increase in fluorescence values at 0 minutes in oxaliplatin treated animals ( Table 2 , first column) as the study progresses, suggesting that some of the imaging agent does not clear out between imaging sessions, but persists in the animals to elevate the baseline.
At the same time, a significant trend in ESR level increase with CAS gradation increase was registered in men ( P = 0.013), which was not registered in women ( P = 0.66).
After adjusting for all factors, the ORs for NHHR tertiles 2 and 3 were 0.76 (95% CI: 0.58–0.99) and 0.70 (95% CI: 0.53–0.94), respectively, with a significant trend ( p = 0.014).
However, there was a significant trend in the increase of PV velocity within 12 postoperative months in the control group compared with the valsartan group ( P =0.014; Figure 4A ).