Barely Significant
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a trend toward significance

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a trend toward significancep = 0.07421.5× alpha
12-month follow-up), a statistically significant difference in MS was observed in the treatment group for the right eye (median MS increased from 24.50 [18.50–27.10] at baseline to 26.00 [22.50–27.70] at 12 months; Δ = +1.50) ( p = 0.0130), while the left eye showed a trend toward significance (median MS increased from 25.40 [15.20–26.70] to 26.10 [17.00–27.30]; Δ = +0.70) ( p = 0.0742).
a trend toward significancep = 0.0751.5× alpha
The repeated measure ANOVA reported a significant main effect of the factor Muscle (F 1,9 = 3.4 p<0.001) and t-test post-hoc comparison showed that both OP and FDI were significantly more activated than ADM (p<0.05), while no significant differences could be reported between the two prime movers OP and FDI, during the pre-shaping and grasping phase of the objects presented, although a trend toward significance was clearly present (p = 0.075).
a trend toward significanceP = .0751.5× alpha
showed a trendP = .0751.5× alpha
Mean total scores on the ESS and Compassion for Self scale and their subscales improved for the intervention group but not for the control group; this improvement was statistically significant for the behavioral subscale of the ESS ( t (8) = 2.86, P = .021) and showed a trend toward significance for the ESS overall ( t (8) = 2.04, P = .075).
a trend toward significancep = 0.0751.5× alpha
showed a trendp = 0.0751.5× alpha
In multivariable linear regression analysis including EI and CA changes, EI reduction emerged as an independent predictor of ALVI reduction (β = 0.55, p = 0.011), whereas CA change showed a trend toward significance (p = 0.075).
a trend toward significancep = 0.0751.5× alpha
Considering the presence of LGE, there was an event rate of 26% (14 of 61) in LGE positive patients compared with 4% (1 of 25) in LGE negative patients (p = 0.041, Log rank), showing also a trend toward significance in Cox regression (HR 6.3, p = 0.075).
a trend toward significancep = 0.0751.5× alpha
Backing these findings, the comparative examination of low-Fuhrman-grade ccRCC patients with and without ADFP expression revealed a higher quantity of VAT in ccRCC patients with ADFP expression, meeting the threshold value ( p = 0.005), along with a trend toward significance indicating elevated TAT values and decreased tumoral HU values in ccRCC patients with ADFP expression ( p = 0.075 and p = 0.070, respectively).
a trend toward significancep = 0.07551.5× alpha
There was no significant relationship between global ICI signal fraction ( T 5,93 = 1.353, p = 0.179 n.s.) or global ICA signal fraction ( T 5,93 = −0.298, p = 0.766 n.s.), but there was a trend toward significance with global ECI signal fraction ( T 5,93 = 1.797, p = 0.0755 n.s.) indicating that AgeAccelGrim may be signaling the presence of extracellular water in the aging brain (Figure 5a ). 3.3.
a trend toward significancep = 0.0761.5× alpha
A Welch’s two-sample t test of PC1 scores revealed that AHR activation showed a trend toward significance ( t = 2.68, p = 0.076), whereas no meaningful effects were observed for other pathways: AR (t = 0.48, p = 0.68), ER ( t = − 0.93, p = 0.43), and SP1 ( t = 0.37, p = 0.74) (Supplementary Fig. 4c ).