Crypt depth showed an increasing trend due to the synbiotic administration on day 4 PI in the Salmonella trial ( p = 0.078), but, contrarily, a decreasing one on day 3 in the ETEC F4 trial ( p = 0.081).
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The frequency of intake of eggs showed an increasing trend ( p = 0.078).
Tumors with a pCR showed additional higher levels of CD45 + , T-cell and cytotoxic cell infiltration (p < 0.05) ( figure 4C ), and an increasing trend of CD8 + T cells (p = 0.078) ( online supplemental appendix figure 8C ).
4 ) and an increasing trend for the species L. gasseri ( P = 0.078; Fig. 4 ).
ZO-2 expression also showed an increasing trend in the CON ( P = 0.078) and HFMT ( P = 0.083) groups relative to the LFMT group.
Compared with the control group, the relative abundance of Bacillota was significantly increased in the BMD group ( P < 0.05), whereas an increasing trend was observed in the L16 group ( P = 0.0781).
5 b), and an increasing trend was noted for Prevotella pallens (p = 0.0781), Candidatus Nanosynbacter lyticus (CP007496_s; p = 0.0977), and Campylobacter concisus (p = 0.0977) (Fig. 5 c–e).
Consequently, the ratio of CD4 + T cells to CD8 + T cells showed an increasing trend in MG patients (P = 0.0783; Fig. 1 B, right panel), reflecting an altered balance between these subsets.
The NP Moraxella EC showed an increasing trend between baseline and Week-2 in the oral suspension group (0.25, −0.03 to 0.53, p = 0.079).
When both ARG and virulence were taken into account, an increasing trend (marginally significant) of their total number over time was observed ( P =0.079).
On day 8, the mRNA expression of PBD-1 and PBD-3 was higher in the GOS group than that in the CON group ( P < 0.05), and the mRNA expression of Reg-3γ displayed an increasing trend to increase in GOS group ( P = 0.079) without any difference in the mRNA expression of IL-8 and IL-10 ( P > 0.05).
Our results indicate an increasing trend ( p = 0.079) in SHR as compared to Wistar rats, and we observed no changes in the expression of ENaC due to melatonin.
Similarly, IL-1β levels showed an increasing trend in the HCA group (Fig. 4B , p = 0.079).
Overall, the strength of PAC in evoked pain was stronger than in baseline ( p = 0.0013, paired signed-rank test; Figure 3D ), and showed an increasing trend compared to spontaneous pain-like episodes ( p = 0.079, Figure 3E ).
The expression of IFN-γ ( p = 0.098) in the jejunum of the HEP group showed an increasing trend, while that of iNOS ( p = 0.079) in the jejunum of the LLEP group showed a decreasing trend.
A significant increase was also observed in MCI plasma samples for miR-181c-5p ( P = 0.0004, log2 fold change = 0.80) and miR-210-3p ( P = 0.0276, log2 fold change = 0.49) whereas an increasing trend was observed for miR-92a-3p ( P = 0.0798, log2 fold change = 0.55).
Compared with the CON and MD groups ( Figure 5 C), cats in the EF group showed an increasing trend in the abundance of Lachnospiraceae ( p = 0.08); notably, Ruminococcaceae exhibited considerably higher abundance ( p < 0.001).
There was an increasing trend of Observed species ( P = 0.08) and Chao1 ( P = 0.09) diversity indices in the Lantang group compared with those of the Landrace group, and the Simpson diversity index exhibited a significant increase in the Landrace ( P = 0.02).
There was an increasing trend in VE concentration in the blood profiles in groups supplemented with 0.02% VE (p = 0.08).
With the increase in the NCG supplemental proportion (0.1%, 0.15% and 0.2%), the monounsaturated fatty acids (MUFA) content showed an increasing trend ( P = 0.08).
Patients aged ≥65 years displayed an increasing trend in their 10-year CHD risk score (1.2%± 7.1%, P =0.08) during the 2019–2020 season compared with the previous 2018–2019 season, which may have contributed to the increased mortality rate in the elderly during the COVID-19 pandemic.
Although there were no significant differences in species richness of the communities associated with the two groups, in each body site ( Supplementary Table 2 ), there was an increasing trend ( p =0.08; inbred higher richness) in the case of the anterior intestine ( Figure 4 ).
However, RBC linear density showed an increasing trend from L1 to L3, which approached statistical significance for L3 versus L1 (p = 0.08, Fig. 2 f).
miR-375 showed an increasing trend, however slightly below the threshold value (p = 0.08), which might be the result of a low sample number.
In contrast, although severe-declining patients reduced endpoint HbA1c to 6.72%, their mean HbA1c remained elevated (7.94%) due to extremely high baseline levels (9.00%), with mortality risk still showing an increasing trend (HR 1.50, 95% CI 0.95-2.37, p = .080).