By further stratifying NEFH variants into high‐frequency rare and ultrarare categories, we identified a similar but albeit weaker significant association for the high‐frequency rare missense tail variants (OR 3.91, 95% CI 1.77–8.64, p fixed‐effect = 0.0007), with ultrarare missense tail variants approaching significance for increasing ALS risk and a showing consistent effect (OR 5.05, 95% CI 0.84–30.22; p fixed‐effect = 0.08).
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Importantly, the MFIS-21 did not have any correlations approaching significance with the robotic assessment tasks.
Therefore, we used a p -value of 0.06 to identify the ASV that was approaching significance and compare this dataset to the OTU dataset.
All significant effects survived multiple comparison correction for FDR ( q ’s < .05), whereas the marginal age × class interaction in the right fusiform/parahippocampal cluster and the marginal class effect in the left lateral/middle occipital cluster were no longer approaching significance ( q’ s > .15). 3.5.
Given that the unemployment was approaching significance it is likely this factor would have reached statistical significance with a larger sample size.
Further, the N1 did not respond to angular differences between reflection symmetry and polarity axes, but there was weak evidence for a larger N1 in PO8 compared to PO7 (F(1,23) = 4.255, p = 0.051, η p 2 = 0.156), with no other effects approaching significance in this model (all p’s > 0.238).
This association was, however, approaching significance, and may be an artifact of the nonparametric statistics employed in the quantitative analysis.
Our cross-sectional findings remain largely unaffected, although one variable (maladaptive coping) which was previously approaching significance has now reached statistical significance.
Interestingly, this locus was approaching significance in association with decreased sensitivities to PPQ, a partner drug in the ACT mostly used at the China-Myanmar border ( Fig. 3 , Supplementary Fig.
Thus statements such as "approaching significance" and "slightly non-significant increase" should be avoided, as the data presented indicated there is not difference.
On the other hand, F1 chimeras reconstituted with parental A/J thymus taken from donors pretreated with cortisone and ALS and then subjected to 1,500 R in vitro irradiation, displayed a more exaggerated preference in helper activity provided to A/J B cells as compared to BALB/c B cells; these differences still were not significant, although clearly approaching significance at the highest helper T-cell dose employed.
38 Why pixatimod should have such a significant effect on viral titers in the nasal turbinates (and approaching significance in the brain), but not lungs in the K18-hACE2 model, is unclear but may reflect very high lung (supraphysiological) K18-driven hACE2 receptor expression in the lungs in this model 44 and/or pixatimod pharmacokinetics. 40 Nevertheless the results are encouraging, especially as recent data suggest th
The association between use of the local radio and feeling informed was approaching significance.
Of the national healthcare systems within the studies, mixed social health insurance was a significant predictor in four complication groups and approaching significance in two additional complication groups.
The adjusted OR was 2.550 (p = 0.093), suggesting a potential combined effect approaching significance.
All groups (including pink noise) experienced an unexpected reduction in positive affect, and none of the differences between groups were found to be significant, though the difference between the 24-minute and 36-minute music with ABS groups was approaching significance and had a medium effect size.
We also found that the relative abundance of the phylum Tenericutes (significantly, q -value < 0.05) and class Mollicutes (differences approaching significance, q -value = 0.069) in subjects with poor sleep quality were lower than in the healthy individuals.
These results were for a small number of subjects with nine subjects receiving zonisamide and nine placebo with the difference between groups in changes in alcohol consumption approaching significance.
After short abstinence, meth elicited significant decreases in Gabra3 (approaching significance for Gabra1 ) mRNA in both sexes.
Based on our current data, we would need at least 19 mice per group to detect the small effect of the chr10 A/J variants in the traits approaching significance at 5 months of age (somatic instability in the liver and intranuclear inclusions), perhaps fewer at a more advanced age where each phenotype is more robustly detected (Wheeler et al. 2002 ).
The ANOVA revealed significant main effect of stimulus type, F (2,16) = 158.75, MSe = 0.16, p<0.001, with no other effects approaching significance.
We did not observe any significant differences in cognitive performance following intervention between equol producers and non-producers, although, within the high-dose group, improvements in spatial working memory in producers versus non-producers were approaching significance.
One of these corresponded to a region of YFV that was not significantly predicted to bind MHC-II (although approaching significance), but it shared a higher than average degree of homology to DENV and the other flaviviruses.
The differences were statistically significant at the first two visits, and a similar trend was observed at the third visit, approaching significance.
Consistent with the overall pattern of non-significant interaction effects (with task responsibility approaching significance), the additional checklist structure did not demonstrate a measurable advantage in teamwork-related SMM alignment within the timeframe of this study.