CSF PlGF correlated positively with all three CDR domains and with ADAS‐total and ADAS‐13 scores and negatively with MoCA and approaching significance for MMSE (Figure 4B ).
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3 ) and by a P value approaching significance (despite the low subject numbers), which was obtained for the longitudinal analysis of the viral load for this group.
4 RESULTS Allele group carriage frequencies for all specificities where associations which were significant, or approaching significance are included in Table 1 .
This association was significant or approaching significance at both sites.
A p value of <0.1 indicates approaching significance. 3.
All three sets of variables were also implicated, albeit only two Day 19 differences, both only approaching significance, involved double bond variables.
The difference between interactions was approaching significance between age groups in the resolution phase.
It also seems unlikely that a trial of this size would have the power to detect a change, and thus, the trial approaching significance did not come as a surprise.
In the MAESTRO trial, where results were approaching significance, it would have been of great importance to have information regarding the hypoxic status of the tumors of each individual patient. 3 Improved hypoxia-activated prodrugs Each HAP candidate is a bespoke invention [42] , [43] , [62] .
Further, donors were selected such that differences in clinical characteristics were as small as possible, where the only characteristic approaching significance is time between EDSS6 and EDSS8.
For the most parsimonious model (leave-one-out analysis at the distance of one standard error), 6 of 9 genes were significantly different between SF-295 and A549, with one not profiled and one approaching significance (Fig. 3 A).
Statistical significance was considered at p ≤ 0.05, while a p -value between 0.05 and 0.08 indicates approaching significance, when shown.
Although the overshoot was unchanged, the AUC Rec and Rec time demonstrated increases approaching significance.
The Bonferroni criteria contrasts indicate that specific pair comparisons do not yield a significant difference, although the contrasts for black/gray and black/blond are approaching significance.
Group 3 made significant improvement in behavioral, emotional, and total engagement, with the increase in cognitive engagement approaching significance.
1e ), with 19 showing significant differences in methylation between first treatment and relapse, and a further three approaching significance ( P FDR < 0.085) (Table 1 ).
Although no cytobands were significantly associated with deletions in DLBCL, we observed that a deletion of the pseudogene ZNF826P in 19p12 was approaching significance (P FDR = 7.84×10 −2 ).
3b ) and drug x segment interactions were only approaching significance and therefore additional post hoc analyses were not completed.
Slowness exhibited a moderate significant correlation, while low physical activity showed a weak-to-moderate correlation, approaching significance.
Additionally, low ETI exposure correlated with increased connectivity approaching significance between default mode (precuneus) and sensorimotor (precentral gyrus (q = 0.054)). 3.5 Early life adversity correlates with alterations in the brain-gut-microbiome system and current mood symptoms Significant relationships were identified between the significant pairs of connected brain regions (Section 4.3 ), four metabolites (glutamate gamma-methyl ester, 5-oxoproline, malate, and urate; Section 4.2 ), and four clinical variables (ETI score, PSS score, HADS anxiety, and HADS depression; Section 4.1 ) ( Table 4 ; Fig. 4 ).
Vascular outcomes found to be significant or approaching significance were used in subsequent multiple linear regression (MLR) analyses to investigate the relationships between total, free, and bioavailable 25(OH)D and vascular outcomes independent of racial group, age, percent body fat and sequentially adjusted for fasting insulin [3] , [17] .
In MCF-7 cells, higher DPP at the same ADR yielded a consistent reduction in the survival fraction, with the 10 Gy comparison approaching significance, an effect that aligned with the expectation that a lower α/β phenotype is more sensitive to large single fractions.
This may increase the likelihood of Type I errors; therefore, the findings, particularly those approaching significance, should be interpreted with caution.
No early mortality (within 30 days) was observed for either group and there were no statistically significant differences between the groups regarding early complications including arrhythmia (approaching significance), acute renal failure (documented by nephrology or requiring dialysis) or readmission.
There was only one association that occurred in a direction opposite to that expected; scratching, which was positively associated with Adaptability at 5 months of age (and approaching significance at 8 months).