“borderline significant”

At the individual site level, each of the six sites showed reductions in energy purchased, ranging from − 15.6 to − 0.3%, which although not statistically significant at any site, were borderline significant at Sites 5 and 6.

It was found that, after adjusting for other socio-demographic factors (gender, school cohort, place of residence, and family affluence): The severity of all symptoms was most strongly associated with time spent on social media, with the strongest associations observed for dizziness and back pain; The weakest associations were observed between the severity of the analyzed symptoms and time spent watching TV or videos; for several symptoms this relationship was not statistically significant (headache, dizziness) or was borderline significant (sleeping difficulties); The goodness-of-fit of the individual GLMs adjusted for four socio-demographic factors ranged from 5.1% (neck or shoulder pain) to 11.8% (dizziness); The goodness-of-fit of the GLMs including only the four screen-time variables as covariates ranged from 3.2% (neck or shoulder pain and eye strain) to 6.3% (dizziness).

Two pediatric subjects who were not allergic to test spores (subjects 3 and 8) and one adult nonaller- gic subject (subject 17) showed significant or borderline significant effects from test fungi on one or two of the three outcomes.

The present study concluded that early initiation of exclusive breastfeeding was borderline significant.

Regarding triple-negative subtype (borderline significant in the present study), Beecher and colleagues analysed it, but since it was not statistically significant on crude analysis it was not included in multiple Cox regression 9 .

In sex‐stratified analyses, the PRS for coronary artery disease, low‐density lipoprotein cholesterol, and lipoprotein(a) were significantly associated with AVC >0 for both sexes ( P <0.05), whereas the systolic blood pressure PRS was borderline significant for women (HR, 1.10 [95% CI, 0.97–1.25]) and significant for men (HR, 1.11 [95% CI 1.00–1.24]).

While not included in the meta-analyses, it is important to note that only the PLS-5 Comp showed borderline significant changes in scores.

Comparing only the ADDITION-NL RC group with the care-as-usual groups, the observed mean differences remained similar and were borderline significant with adjusted mean differences of 1.2 mmol/mol (95% CI −0.2 to 2.7) (0.1% (95% CI −0.0 to 0.3)) and 1.5 mmol/mol (95% CI −0.0 to 2.9) (0.1% (95% CI −0.0 to 0.3) ( table 2 ).

However, some variables were found to be borderline significant.

Including only non‐secretors in the multivariate analysis showed a borderline significant slightly negative correlation between fiber intake and relative HMO‐bound fucose levels.

Further, a borderline significant increase in transmucosal oxygen saturation was observed after the intervention.

8 In the Effectiveness of Intravenous Iron Treatment versus Standard Care in Patients with Heart Failure and Iron Deficiency (IRONMAN) trial ( NCT02642562 ), FDI in patients with LVEF ≤45% (hereafter referred to as HF), resulted in a borderline significant reduction in HF hospitalisations and cardiovascular (CV) deaths (statistically significant in the prespecified COVID-19 sensitivity analysis), as well as improvement in QoL at 4 months, compared with usual care (UC). 9 To aid shared decision-making, it is important to understand the efficacy and safety of FDI in patients with HFrEF in different age groups.

P -values of less than 0.05 were considered to have significant association between the outcome and the explanatory variables, and P-values of less than 0.1 were considered borderline significant.

The calibration slope test was borderline significant meaning that the model required a small amount of recalibrating which is usual in external validation (more detail in Appendix S4 ).

Furthermore, in a supplementary analysis, the positive association was significant only for calcium channel blockers and borderline significant for diuretics.

P values between 0.10 and 0.05 were considered to be borderline significant.

The model statistics of p(F-test) ≈ 1.22 × 10 −6 , BEpot p( t -test) ≈ 1.85 × 10 −3 , BSvdw p( t -test) ≈ 0.0017, and BindPack1D p( t -test) ≈ 0.04 indicate that the model R 2 adj and individual contributions are statistically significant, although the BindPack1D term is only borderline significant.

When sex-by-age interaction terms were statistically significant or borderline significant, predictive margins were estimated by sex at selected age values of 18, 25, 35, 45, 55, and 65 years to facilitate substantive interpretation of the interaction pattern.

Interestingly, BMI showed a borderline significant negative association with EQ-5D in the overall cohort and in the interspinous group, suggesting that higher BMI may slightly limit perceived quality-of-life improvements.

The P2RY11 SNP rs2305795 risk allele A was borderline significant in a single, small post-H1N1 NT1 study by Bomfim et al.

WSE correlated with mutations in the genes SMARCB1 (p=0.002), Ataxia telangiectasia mutated (p=0.004), Kinase Insert Domain Receptor (p=0.006), and were borderline significant in RET and EGFR exon.

The same authors also reported that radio-induced thyroid tumors during childhood were characterized by significantly increased levels of DUOX1 gene expression compared with normal thyroid tissues, while in sporadic thyroid tumors, the increase in DUOX1 level was borderline significant, identifying DUOX1 as a major source of radio-induced oxidative stress and, as such, capable of promoting genomic instability and inducing TC [ 91 , 112 ].

(2021) reported among the whole cohort a non-significant SMR for nervous system diseases compared with national rates based on 815 deaths, but a borderline significant increase in mortality due to Parkinson’s disease was observed (SMR = 1.16; 95% CI: 1.00, 1.34; n deaths = 193), and a positive dose–response relationship was suggested (ERR at 100 mGy = 0.16; 95% CI: −0.07, 0.40; n deaths = 273) [ 33 ].

When adjusted also for BMI this difference became borderline significant.

After adjusting for diseases related to pregnancy in the MADT sample, we found overall the same results as in the main analysis, with higher mortality and more hospitalizations among women with a TTP of ≥18 months, although the association with mortality became borderline significant ( Supplementary Table SVIII ).