did not quite reach significancep = 0.0245
However, the increase in the ratio of pNF-κB/ NF-κB in the combination treatment group did not quite reach significance (control 0.59 ± 0.12; H398, 0.69 ± 0.13; EHD-sc-mTNF R2 1.00 ± 0.03, p = 0.0245; H398 + EHD-sc-mTNF R2, 0.94 ± 0.057) (Fig. 4 J–L).