“did not reach statistical significance”

Furthermore, there was a strong trend for IMI to reduce fever caused by PRRSV infection, but the effect did not reach statistical significance (p = 0.058; Fig. 2C ).

Additionally, an increasing trend was observed in the expression of ALP (3.68-fold increase) and COL1 (1.20-fold increase), although these changes did not reach statistical significance ( Figure 6 ).

Although differences did not reach statistical significance (probably due to the small number of patients), there was a clear trend for increased cholesterol, LDL, waist circumference, and body mass index values in the patients with suboptimal adherence in our study.

Meta-analysis for diabetes DTx showed a trend toward improved hemoglobin A 1c levels in digital intervention groups compared to controls (SMD −0.96, 95% CI −2.03 to 0.11) but did not reach statistical significance ( I 2=97%).

In contrast, nano-ALA 250 PDT also showed a trend toward reduced DHE fluorescence, but the change did not reach statistical significance ( P > .05) ( Figure 4 A, B).

The results of the meta-analysis were consistent with these findings, with an overall trend toward greater SAF in smokers than in non-smokers for similar age groups, but the difference did not reach statistical significance ( Supplementary Table S7 , Figure S9 ).

There was a slight trend toward more late apoptosis with PFD treatment, but this did not reach statistical significance (p=0.283, p>0.05; Figure 6B ).

Survival analysis showed a trend toward improved overall survival in KRAS -wt EO-PDAC patients, although the difference did not reach statistical significance (52 versus 26 months, HR 2.27, 95% CI 0.78-6.66, P = 0.13) ( Supplementary Figure S3 , available at https://doi.org/10.1016/j.esmogo.2025.100179 ).

History of blood transfusions displayed a positive trend in association with HCV Ab positivity, but did not reach statistical significance.

Although no significant differences were observed in the expression of other genes, the expression levels of gastrointestinal growth-related genes in the 14 d group showed an increasing trend compared to both the 7 d and 21 d groups, but these differences did not reach statistical significance ( p > 0.05).

Blood pressure was lowest in the LPS group, but despite a clear trend, the decrease in this group compared to the control group did not reach statistical significance ( Figure 2 ), possibly due to volume resuscitation and variability among animals.

In the present study, inclusion of a single lap belt PT in addition to the shoulder belt PT showed a trend of reducing submarining risk for the reclined FE-HBMs, although this effect did not reach statistical significance for the simulation sample (p = 0.22).

A positive trend between β-carotene and CSF TNF-α was also observed, however this did not reach statistical significance ( P = 0.17).

The difference between obese and non-obese patients in the higher SML group showed a clear trend but did not reach statistical significance(median CSS: 605.0 days vs. 1196.0 days, P = 0.330, Fig. 4 b).

A history of hypertension showed a trend toward a negative association that approached, but did not reach statistical significance (adjusted OR = 0.424, 95% CI: 0.178–1.009; p = 0.052).

In the overall analysis, 0 % anti-inflammatory intake showed a trend of reduced AD-specific mortality although its did not reach statistical significance after full adjustment (HR 3.04, 95 % CI 0.74–12.46 vs. ≥10 % intake; p>0.05).

Changes in visual acuity and macular edema were secondary outcomes in our study, showing only a mild trend toward improvement that did not reach statistical significance.

Compared with the OPS group, the MIS group showed a trend towards lower overall complication rates, but this did not reach statistical significance (OR=0.78, 95% CI [0.59–1.03], P =0.08), neither for PD (OR=1.10, 95% CI [0.43–2.79], P =0.84) nor for DP (OR=0.73, 95% CI [0.53–1.01], P =0.06).

The effect was dose-dependent; treatment with lower doses of Rac1 peptide showed a trend toward improvement, and this trend did not reach statistical significance (Figure 2a, b ).

Analysis of GCL nuclear counts showed a trend for increase GCL counts with LNAM treatment though this did not reach statistical significance (Fig. 5 G).

In addition, there was a significant trend towards increased SREBP-1c and SCD1 protein levels in the liver; however, this increase did not reach statistical significance.

While the GMV of the left thalamus in patients with dystonia (mean ± SD: 7092.346 ± 816.061) showed a trend towards reduction compared with that in healthy controls (mean ± SD: 7224.300 ± 927.542) ( P uncorrected = 0.011), it did not reach statistical significance after correction for multiple comparisons.

Radiologic severity, assessed by stricture index (SI), showed a trend toward lower values in the OVB group but did not reach statistical significance (0.41 [IQR 0.38–0.52] vs. 0.52 [IQR 0.42–0.56]; p = 0.063) ( Table 4 ).

Compared to the ICL group, the PSS group showed a trend toward reduced microbial diversity; however, this difference did not reach statistical significance (Shannon index: p = 0.065; Simpson index: p = 0.066).

In the complete case analysis, long shifts showed a trend toward increased sleep-aid use but did not reach statistical significance (OR 1.64, 95% CI 0.99–2.66) ( Data Supplement 3 ).