“did not reach statistical significance”

Although some markers did not reach statistical significance, SOF10 showed a trend toward suppressing TGF-β downstream targets Serpine1 , Col1a1 , and Col3a1 (Fig. 3d ).

Similarly, while CFU-E colony numbers showed a trend of increase with SRT2104 treatment (no SRT2104, 27.1%±4.7%; SRT2104, 35.7%±8.3%), this difference also did not reach statistical significance ( Fig. 4A ).

In the independent GEO cohort GSE39582 , DMBX1 expression showed a trend toward higher levels in colorectal cancer tissues compared with normal mucosa, although the difference did not reach statistical significance (Wilcoxon rank-sum test, p = 0.083).

Sarcoma showed a trend toward an increased risk; however, this association did not reach statistical significance ( P = 0.051) (Table 3 ).

Regarding emotional symptoms, we observed a decreasing trend in depressive and anxiety symptoms, although it did not reach statistical significance.

Principal component analysis (PCA) also showed a trend toward spatial separation, indicating molecular heterogeneity between the groups; however, due to limited sample size and within-group variability, the 95% confidence intervals partially overlapped, and the separation did not reach statistical significance ( Figure S7 G ).

However, a numerical trend toward lower mortality was observed in the post-intervention group, suggesting a potential clinical benefit that did not reach statistical significance.

Compared to the AD group, the levels of Tau, P‐tau, BACE1, and PS‐1 showed a decreasing trend after APS treatment and were positively correlated with concentration, although the differences did not reach statistical significance.

Additionally, a high density of CD8 + TILs at the invasive front showed a trend toward better prognosis, although this association did not reach statistical significance ( p = 0.089). 4.4.

pqsA expression showed a decreasing trend, although this did not reach statistical significance ( p > 0.05).

Although a decreasing trend was also observed throughout the entire time course also for LCAT, particularly at the 4-hour mark, this trend did not reach statistical significance (data not shown).

While it also showed a positive trend for anxiety improvement, the between-group difference in final anxiety scores did not reach statistical significance. 85 These mixed and preliminary findings underscore that there is currently no standardized pharmacological protocol for treating anxiety in TD.

Regarding antioxidants, unlike bilirubin, the level of uric acid showed a trend of increasing in overweight/obese adolescents; however, it did not reach statistical significance.

Phosphorylated TH, phosphorylated CaMKII, and dopamine protein levels showed an increasing trend in the model group, although these differences did not reach statistical significance.

A/S + 40 Hz group exhibited an increasing trend compared with the A/S group, though the difference did not reach statistical significance, while alpha coherence increased significantly.

A positive trend was observed for folic acid intake, although it did not reach statistical significance ( p = 0.061).

A marginal trend was observed for semantic fluency, but it did not reach statistical significance.

Although the probiotic group showed a trend towards reduced plasma CRP-levels, this effect did not reach statistical significance.

Additionally, SKCM patients with low GPR37 expression showed a trend toward longer overall survival following immunotherapy, though this difference did not reach statistical significance ( P = .061; hazard ratio [HR] = 1.77, 95% CI 0.92–3.02; Fig. 7 A).

Concentration was inversely related to pollution levels (SMD ‐0.14; 95% CI ‐0.21 to ‐0.06; P < .001), while sperm count showed a trend toward reduction but did not reach statistical significance (SMD ‐0.12; 95% CI ‐0.26 to 0.01; P = .06).

For menstrual pain duration, the intervention group showed a trend toward fewer pain days compared with the control group; however, this difference did not reach statistical significance in adjusted analyses.

The right spinal cord gray matter showed a trend toward activation for the medium and high task levels, but the magnitude of activation did not reach statistical significance.

In Ad.GFP-infected cells, the mitochondrial fission protein Drp1 showed a trend toward reduced levels; however, this change did not reach statistical significance.

Fecal moisture content showed an increasing trend in the JCJ-HYD, NF-HYD, FNF-HYD, and FNF/2-HYD groups; however, these changes did not reach statistical significance ( Figure 4 H).

In contrast, the Shannon diversity index exhibited a decreasing trend in the F group, although this change did not reach statistical significance ( p > 0.05).