“did not reach statistical significance”

In addition, Sirt1 knockdown showed a trend toward a 17.58% increase in the p-p65/p65 ratio compared with the Bmal1 overexpression group, although the difference did not reach statistical significance ( Figure 5D ).

Patients with high CRP levels and/or adverse molecular markers, such as FLT3-ITD positivity, also showed a trend toward poorer survival, which, however, did not reach statistical significance in the multivariate model.

The results demonstrated significantly elevated Foxp3 expression in the spleen of PCV2-infected piglets, while lymph nodes showed an increasing trend that did not reach statistical significance ( Fig.

The control group showed a trend towards a decline in ALBI scores, but did not reach statistical significance at 12 months (P=0.11).

Comparison of cell-type composition revealed that the proportion of CD25 + cells within the CD4+ T cell compartment showed an increasing trend in non-survivors compared with survivors at both the sample and cell levels, although this difference did not reach statistical significance (Additional file 2: Figure S3).

Intrapartum complications Gestational diabetes mellitus showed a trend towards increased odds (OR = 1.37; 95% CI: 0.70–2.69), but this association did not reach statistical significance ( p = 0.352).

A platelet count ≥100×10 9 /L, aspartate aminotransferase < 80 U/L, lactate dehydrogenase <500 U/L, and receipt of anti-tumor therapy showed a trend toward better survival but did not reach statistical significance ( P = 0.086, P = 0.075, P = 0.059, and P = 0.080, respectively).

Although both normal weight (OR = 0.25,95% CI:0.06 ~ 1.03, p = 0.05) and overweight (OR = 0.11, 95% CI:0.01 ~ 1.25, p = 0.08) groups showed a trend toward reduced risk compared to the underweight reference group, these associations did not reach statistical significance in multivariable model.

Although IFN‐α also showed an increasing trend, it did not reach statistical significance.

Although the differences in positivity rates across dormitories did not reach statistical significance after adjustment for multiple comparisons, the data nonetheless indicated a pronounced trend toward concentrated infection intensity in specific rooms, particularly those allocated to Class 2302.

Similarly, the orbitofrontal and infralimbic areas showed a trend toward an increase in the number of KCNN2 + cells, although this did not reach statistical significance ( Figure 2A , B ).

Cys-C levels showed a decreasing trend following AVLE treatment, although the difference did not reach statistical significance ( Figure 1I ).

A strong trend toward a higher total postoperative complication rate was observed in the laminectomy group (n=12, 24%) compared to the laminoplasty group (n=2, 4%), though this did not reach statistical significance (p = 0.062, Fisher's exact test).

Age showed a trend toward increased risk but did not reach statistical significance.

Relationship Between Obesity and Malnutrition and the Severity of AP When analyzing obesity separately, there was an overall trend of increased risk of AP severity with increasing BMI (p trend=0.012), but the individual analysis of each group did not reach statistical significance.

The funnel plot ( Figure 3 ) and Egger’s test revealed no evidence of small-study effects or publication bias across all subgroups, with the exception of the DM subgroup, in which a weak trend towards small-study effects was noted; however, this did not reach statistical significance ( p = 0.0746).

An increasing trend in proteinuria with higher sodium intake was observed in individuals with diabetes, although this did not reach statistical significance ( S1A and S1B Figs ).

The difference between SL9 and SL12 showed an increasing trend but did not reach statistical significance.

As shown in Figure 1 A–C, the expression levels of Acta2 and Col1a1 were significantly elevated in the CKD group compared with those in the Normal group ( p < 0.001), whereas Tgf-β1 expression showed an increasing trend but did not reach statistical significance.

Although symptom duration < 24 h and age > 75 years showed a trend toward increased odds of successful conservative management, these associations did not reach statistical significance. 4.

The absence of pCR following neoadjuvant chemotherapy showed a trend toward increased progression risk (HR = 2.15, 95% CI: 0.83–5.55), but this did not reach statistical significance ( p = 0.113).

Although zebrafish treated with P3 (6 mg/L) showed a trend toward increased preference for novel object exploration, the effect did not reach statistical significance compared to the control group, suggesting a more modest or inconsistent impact of this formulation on recognition memory. 3.3.

In contrast, sessions ≥30 min showed a trend toward improvement, but the pooled effect size did not reach statistical significance (SMD = −0.36, 95% CI [−0.75, 0.04], p = .08; I2 = 79%).

Radiologic severity, assessed by stricture index (SI), showed a trend toward lower values in the OVB group but did not reach statistical significance (0.41 [IQR 0.38–0.52] vs. 0.52 [IQR 0.42–0.56]; p = 0.063) ( Table 4 ).

2 b) did not reach statistical significance, both measures showed a trend toward increased anxiety-like behavior.