Lastly, in the smaller subset of patients with GS 3 + 4 = 7 carcinoma [Subset: GS = 3 + 4 = 7 (i.e., Grade Group 2), N = 341 patients], patients with cribriform glands >0.25 mm showed a trend toward lower RFS that was not seen in patients with cribriform glands of any size; however, this finding did not reach statistical significance (univariable p = 0.1).
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In the literature
In support of this notion, male KO mice also showed a trend towards an increased latency to enter the bright compartment of the testing apparatus, albeit this trend did not reach statistical significance ( t (9) = 1.55, p = 0.15) (Fig. 3 A).
However, the changes in these two indices did not reach statistical significance but displayed a decreasing trend in the T1D + NaB group compared with the T1D group (Fig. 3 F, G).
HCW animals showed a trend of worse behavioral and eating performance, but this did not reach statistical significance ( Table 2 ).
a strong trendgold
There was a strong trend toward higher SWV in pitchers as compared to volunteers, although the difference did not reach statistical significance ( P = .056).
Additionally, patients who received radiotherapy at multiple sites showed a trend to have improved OS compared to those who received radiotherapy at a single site, although the difference did not reach statistical significance.
a positive trendgold
IHC score showed a positive trend with CD73 mRNA expression in all HGG cases with bulk sequencing from the larger CBTTC cohort ( n = 39), though this did not reach statistical significance ( p = 0.052; n = 39) (Fig.
In cELS of distended preparations incubated with both AZ10606120 and BzATP, the eATP decrease showed a trend to be lower than observed for distended preparations incubated with BzATP alone, but this difference did not reach statistical significance ( Figure 5 b).
There was a slight trend for a higher age among patients who died, even though it did not reach statistical significance.
Regarding the laterality effect of noise trauma, the PAC was significant only on the contralateral side ((contralateral noise-exposed (N) = 4157, control (C) = 3297, p = 0.02), (ipsilateral N = 4563, C = 3941, p = 0.34)); changes in contralateral MGB showed a trend, but did not reach statistical significance ((contralateral N = 4405, C = 3829, p = 0.07), (ipsilateral N = 4600, C = 3965, p = 0.14)); and the CA1 was significant bilaterally ((contralateral N = 6325, C = 5252, p = 0.03), (ipsilateral N = 6727, C = 5690, p = 0.04)).
The mean AET decreased significantly by 2.39%, and the DeMeester score showed a trend toward improvement, even though it did not reach statistical significance [ 72 ].
The mRNA expression levels of Acc increased ( p = 0.074) in HFHC-fed mice compared with CD-fed mice, indicating that there might be an increasing trend that did not reach statistical significance.
In comparison, sTACI-Fc–treated groups showed a trend toward reduced tumor growth that did not reach statistical significance.
The total number of proliferating cells estimated by Ki67 showed a decreasing trend in GBS-infected mice as compared with the saline group, which did not reach statistical significance (not shown).
PDAC outgrowth length showed a decreasing trend upon sodium selenite treatment but did not reach statistical significance.
When samples were divided according to the extent of SerpinB3 expression, tumors expressing a high level of SerpinB3 (>median value) showed a trend toward higher amounts of Wnt-1 and Wnt-7a compared to the corresponding figures observed in tumors with low SB3 level (<median value), although the difference did not reach statistical significance, probably due to the small sample size ( Supplementary Figure S1 ).
In Group I, GAL showed a trend to lower activity and lyso‐Gb3 to higher levels in women with the mutated X‐chromosome active compared to those with the mutated X‐chromosome inactive, however, differences did not reach statistical significance (Figures 2 and 4a,b ).
An overall trend toward an increase in BMI was observed at the long-term follow-up that however did not reach statistical significance due the small sample size, but in the majority of participants BMI changes were stable or improving over time [ 80 , 81 ].
Gene expression analysis showed that baseline TAF1 levels differed between control and patient fibroblast cell lines, and treatment with CORT led to an increasing trend in the expression of the aberrant TAF1-32i transcript but did not reach statistical significance.
The medium effect sizes indicate that although the study may have been underpowered due to a small sample and therefore did not reach statistical significance, there is an effect of medium importance in the cognitive areas of selective attention and language that may be significant in larger, more heterogeneous samples.
In children with 22q11DS, FW span and BW span showed a trend towards a moderate correlation, but this did not reach statistical significance ( r (36) = 0.29, p = 0.083, 95% CI [− 0.04–0.57]).
Conversely, the PD-risk factor T408M (also known as T369M, rs75548401) showed a trend toward a faster rate of cognitive decline that did not reach statistical significance, in keeping with a previous study. 43 The mild GD-causing variant N409S (also known as N370S, rs76763715) has shown inconsistent association with cognitive decline in PD.
However, in their meta-analysis, the results showed that combined mortality had a favorable trend but did not reach statistical significance ( P = 0.064), which included one trial in common with our analysis[ 19 ].
Donors' statin use showed a trend for a similar association to occurrence of biliary‐vascular complications as recipient statin use: HR = 0.47; 95% CI = 0.22–1.02, but it did not reach statistical significance ( p = 0.056). 3.5.
Oppositely, we found an increasing trend, but the result did not reach statistical significance.