A slight reduction in fasting insulin and HbA1c was observed, though these changes did not reach statistical significance ( Figure 7 A; SMD: −0.194, 95%CI=−0.332 to −0.056; I2 =39.386%, p =0.022) and ( Figure 7 B; SMD: −0.151, 95%CI=−0.294 to −0.009; I2 =17.400%, p =0.254), respectively.
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However, evaluating intrapatient change in radiolucent line width, the tobacco nonuser group had more radiolucent lines resolve by the latest follow-up in nearly all radiographic zones, although most differences did not reach statistical significance, except for anteroposterior zone 1 (−31% vs −19%, P = .022).
Formal interaction models including group, PSQI total score, and their interaction term did not reach statistical significance ( B = 0.200, r = 0.417, p = 0.022; 95% CI: 0.032–0.369), likely reflecting limited statistical power; however, the stratified analyses demonstrated a clear divergence in sleep–pain associations between insomnia and COMISA groups.
In two cases, this difference did not reach statistical significance. 36 , 44 Risk of bias assessment The Egger’s regression intercept test was significant ( t = 2.22, P = 0.022), suggesting the presence of a publication bias in reporting the main outcome.
Notably, HA users reported lower HHIA scores than non-users, but this difference approached but did not reach statistical significance after Bonferroni correction (t = −2.29, p = 0.023; adjusted α = 0.017).
However, although a benefit in median PFS was observed, it did not reach statistical significance: median PFS was 6.5 months (95% CI, 5.7-6.9) in the experimental arm and 5.6 months (95% CI, 5.1- 6.6) in the control arm (HR, 0.86; 95% CI, 0.75-1.00; P =0.023).
Although SIRT1 levels were increased in the Se group compared to the control group, it did not reach statistical significance. In the CS group, an increase in Bax expression and a decrease in Bcl-2 and PGC1-α expressions were observed compared to the control group ( p = 0.023, p = 0.011, p = 0.003; respectively).
The differences in RFS between the IRF-1 negative and positive groups did not reach statistical significance after Bonferroni correction (Figure 5A , P = 0.023, Bonferroni correction α′ = 1.5 × 10 −3 ).
Known-group comparisons Caregiver burden measured with ZBI-7 was significantly higher for female caregivers The results for the outcome ZBI-1 did not reach statistical significance, based on the Bonferroni-corrected alpha level of 0.006 (ZBI-1 t = 2.32, p = 0.023; ZBI-7 t = 2.96, p = 0.004).
Among 107 patients receiving conventional radiotherapy, median changes in FEV 1 and 6MWT from baseline were also greater in those who received PR (n=6) than in those who did not (n=101), although 6MWT changes did not reach statistical significance (FEV 1 , 270 mL vs. −10 mL; p=0.023 and p=0.036, respectively) ( Table 3 ). 5.
However, it is important to note that this value did not reach statistical significance ( p = 0.023).
did not reach statistical significancep = 0.0233
Although the correlation coefficient between serum PG I/II ratio and HOMA2%B did not reach statistical significance, the partial correlation test confirmed this negative relationship after adjusting for age and gender (partial correlation coefficient r = −0.0778, p = 0.0233).
Although results from the final analysis showed that improved overall survival when compared with placebo, the differences did not reach statistical significance per predefined criteria (HR=0.781; 95% CI=0.611–0.998; p=0.0238).
Intermediate chronotypes also scored better than evening chronotypes although the difference did not reach statistical significance ( p = 0.024, Cohen’s d = 0.22) (Fig. 1 ).
An interim OS analysis was performed among the all-comer population with only 43% data maturity and did not reach statistical significance (HR = 0.82; 95% CI: 0.63–1.07; p = 0.024).
The ICNARC study investigators found higher survival rates in female patients with pneumonia [ 8 ], but the 30-day survival advantage in older female patients with pneumonia did not reach statistical significance ( P =0.024) in our present study.
The difference between volleyball players and track-and-field athletes did not reach statistical significance after Bonferroni correction (χ 2 (2) = 7.43, p = 0.024, Bonferroni-corrected p = 0.073), likely reflecting limited statistical power and the substantial chronological age disparity between these subgroups.
28 An 8-week Pilates program achieved a medium-to-large effect on functional performance (η 2 = 0.45), though between-group differences did not reach statistical significance. 29 A self-directed 6-week walking program also demonstrated significant improvements in WOMAC function and stiffness subscales ( P = .024 and P = .043, respectively), 31 indicating moderate enhancement of mobility and daily activity tolerance.
mansoni -infected groups for cTfh17 cells pre-vaccination did not reach statistical significance, they were significantly lower in S . mansoni -infected individuals at M12 post-vaccination (no vs. low P = 0.024, no vs. high P = 0.006) ( Fig 4E ).
However, the group effect did not reach statistical significance [F (3, 40) = 3.48, p = 0.024, ηp 2 = 0.207].
the GA or GA+AA phenotype but the differences did not reach statistical significance after multiplicity adjustment (42.6% vs. 27.6%, p = 0.024; 42.6% vs. 27.4%, p = 0.015).
Although RNI did not reach statistical significance in univariate analysis, it exhibited a significant protective effect after multivariate adjustment ( P = 0.024).
The study did not reach statistical significance in the intention-to-treat population, with a median PFS of 5.7 months for selinexor versus 3.8 months for the control arm (HR 0.70; p = 0.024).
The 24-h body weight showed a trend of reduction, but this change did not reach statistical significance upon GALP treatment ( p = 0.0247) (Fig. 6 b).
However, while NRP2A showed a weak but significant correlation with PDGFD, the correlation of NRP2B and PDGFD did not reach statistical significance (ρ = 0.12; p = 0.025 and ρ = 0.05; p = 0.32, respectively).