However, these differences did not reach statistical significance ( p = 0.020 and p = 0.101).
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Thereafter, the plasma levels of mtDNA in the patient group continued to increase compared with those of the control group (t 72 ), but did not reach statistical significance (controls: 65 (28–119) copies/μL; patients: 281 (110–805) at t 0 , 403 (168–1937) at t 24 and 467 (188–952) copies/μL at t 72 ; controls vs. patients: p = 0.02 at t 0 , p = 0.03 at t 24 and p = 0.44 at t 72 ; Figure 1 B).
Although the treatment time-point by group interaction did not reach statistical significance, a significant decline ( p = 0.02) in performance from baseline to treatment was found in the placebo group.
pylori infection (HR: 0.49, 95% CI 0.26 to 0.89), but the results did not reach statistical significance (p=0.020).
Although the relationship between migration destination and type of departure approached significance (χ2(1) = 3.12, p = 0.02), it did not reach statistical significance.
This outcome, whose individual components did not reach statistical significance, occurred in 35.5% of patients on treatment vs. 38.5% in the placebo group [relative risk (RR), 0.90; 95% confidence interval (CI), 0.82–0.98; P = 0.02]; 16.4% of patients on treatment and 17.5% of patients in the placebo arm died of cardiovascular causes (RR, 0.93; 95% CI, 0.81 to 1.06); 27.4% of patients on treatment and 29.6% in the placebo group were hospitalized for HF (RR, 0.90; 95% CI, 0.81–1.00).
AdAg85A vaccine i.n and i.m boosting to BCG-immunized animals further significantly enhanced it to 467 and 412 days, respectively although the differences between BCG and BCG/Ad i.m groups did not reach statistical significance ( Fig. 5 ; p = 0.02 BCG/Ad i.n compared to BCG alone; p = 0.12 BCG/Ad i.m compared to BCG alone).
However, the associations for the vmPFC and left anterior insula did not reach statistical significance (pairwise correlations: left striatum, r = − 0.36, p = 0.02; right striatum, r = − 0.35, p = 0.03; left anterior insula, r = − 0.19, p = 0.23; right anterior insula, r = − 0.35, p = 0.02; vmPFC, r = − 0.22, p = 0.12).
Still, this difference did not reach statistical significance except in the group who were initiated on 10 mg daily of finerenone titrated up to 20 mg daily (hazard ratio 0.56, 95 % confidence interval 0.35–0.90, p = 0.02) [19] .
However, upon further adjustment for lifetime smoking, the effect sizes of the association slightly attenuated and did not reach statistical significance after Bonferroni correction (OR: 0.986; 95% CI: 0.975–0.998; p = 0.020) (Fig. 4 ).
Students who prepared for the exam by means of elearning (M = 1.8) had better marks in the exam than students who did not prepare by means of elearning (M = 2.5); however, this effect did not reach statistical significance (U = − 2.34; p = .02).
There was a strong trend toward increasing arginase I level in pancreatic cancer, which did not reach statistical significance ( P = 0.020).
gastroenterology, endocrinology) before coming to program than those with other EDs (26.1%), although this did not reach statistical significance with the Bonferroni correction ( p = 0.02).
The difference between IOP of injected eyes and their contralateral controls averaged over the course of the experiment was an increase of 3.8 +/− 2.81 mm Hg for vehicle-treated and 5.5 +/− 4.21 mm Hg for telmisartan-treated mice (mean +/− SD), but this difference did not reach statistical significance (except at day 14, P = 0.02, Student's t -test).
Single-Parent Poverty & Maternal Substance Use: M difference = 5.12, p = .01, FDR p = .02), and higher estimates than males in Maternal Substance Use at age 15, but did not reach statistical significance after FDR correction ( M difference = 3.19, p = .02, FDR p = .10).
In lesional skin, the AUC-increase compared to day 1 was pronounced but did not reach statistical significance ( p = 0.020) considering Bonferroni.
Maximal exercise Average VO 2max and W max in the patients was less than half that in the healthy controls (Table 1 ), though difference in W max did not reach statistical significance ( P = .02 and P = .07, respectively).
1 A and graphical abstract), which did not reach statistical significance, but a 19% reduction (RR 0.81; 95% CI: 0.69 – 0.95, p = 0.02) when the analysis was restricted to 14 days from randomisation (5/11 trials, 1329 patients) ( Fig. 1 B).
A negative correlation was observed between the left DTI-ALPS index and HbA1c, but this result did not reach statistical significance after multiple comparison correction (r = −0.508, p = 0.021).
Patients with type A dissections had odds of in-hospital mortality 3.3 times greater than those with type B, but did not reach statistical significance ( p = 0.021).
did not reach statistical significancep = 0.0210
The analysis revealed significantly elevated levels of IL-6, IL-8, and IL-10 in the infection group, while IL-17A did not reach statistical significance as depicted in the heatmap (21.26 pg/ml vs. 7.63 pg/ml, p = 0.0210; 20.38 pg/ml vs. 13.02 pg/ml, p = 0.0050; 10.99 pg/ml vs. 5.63 pg/ml, p < 0.001, respectively, Figure 5 ).
46 Although the pooled effect size (Hedges’ g=0.07, 95% confidence interval −0.08 to 0.22, P=0.360) was small and did not reach statistical significance, there was notable variation across intervention types—most prominently in dialectical therapy (g=0.361, P=0.021).
Among patients with low comorbidity (CCI ≤ 3), the differences in inflammatory markers between CC and RC were relatively modest and did not reach statistical significance, except for lymphocyte counts, which remained significantly lower in CC ( p = 0.022).
In two cases, this difference did not reach statistical significance. 36 , 44 Risk of bias assessment The Egger’s regression intercept test was significant ( t = 2.22, P = 0.022), suggesting the presence of a publication bias in reporting the main outcome.
A slight reduction in fasting insulin and HbA1c was observed, though these changes did not reach statistical significance ( Figure 7 A; SMD: −0.194, 95%CI=−0.332 to −0.056; I2 =39.386%, p =0.022) and ( Figure 7 B; SMD: −0.151, 95%CI=−0.294 to −0.009; I2 =17.400%, p =0.254), respectively.