Activation was visually observed in four additional subjects but did not reach statistical significance ( p < 0.05) (example Figure 3 , subject 5, other three subjects shown in Supplementary material 4 ).
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“did not reach statistical significance”
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However, this association did not reach statistical significance at the P <0.05 level.
interaction term between study year and education; other tested combinations did not reach statistical significance at p < 0.05) Model 1, the effects were slightly attenuated, but retained their significance with substantial variance in SSB consumption by study year, sex, age, and education.
The calculated tests of between-subjects effects (factor 1) did not reach statistical significance with a level of P <.05 ( F 2,39 =0.58, P =.58; partial η 2 =0.03, 1–β=.13).
showed a trendP > 0.05
Regarding fibrosis indicators, although PCSK9i use showed a trend toward improvement in Δ APRI (β = −0.021) and Δ FIB-4 (β = −0.19), these associations did not reach statistical significance in the adjusted model ( P > 0.05).
It should be noted that this difference did not reach statistical significance based on the Mann-Whitney U test (U = 61; the critical value of U at p < 0.05 is 45).
Although the difference did not reach statistical significance of p=0.05 at most time points, we cannot exclude the possibility that this finding could be due to type II errors.
Among the 52 patients in each group matched for age, ECOG PS, and treatment response to R‐MVP, median PFS was not reached in the ASCT group and was 90.0 months (95% CI 41.0–NR) in the WBRT one, but the difference did not reach statistical significance ( p = 0.050, Figure 2A ).
The decrease seen in medication infusion discrepancies did not reach statistical significance ( p = 0.05).
Importantly, 26 hallmark sets (out of 50 total tested) that previously did not reach statistical significance were significant (adjusted P <.05) in the updated PDAC compendium.
showed a trendp > 0.05
Although inflammatory markers such as tumor necrosis factor-alpha (TNF- α ), interleukin-6 (IL-6), and C-reactive protein (CRP) showed a trend toward elevation in SAE patients, these differences did not reach statistical significance ( p > 0.05, Supplementary Table S2 ).
Site of onset did not reach statistical significance ( p < 0.05), but met the criteria required for inclusion in the logistic regression model (Fisher's p = 0.082; Table 4 ).
Later age of symptom onset (70+ years) was associated with lower odds of genetic testing completion (OR 0.23; 95% CI 0.12–0.43; P < 0.001) compared to the reference group (10–19 years), while early symptom onset (0–9 years) showed a trend toward higher odds of genetic testing completion that approached but did not reach statistical significance (OR 1.53; 95% CI 1–2.37; P = 0.05).
Interactions between RAS inhibitor and MRA (OR=0.72, 95% CI: 0.49-1.04, p=0.08) and between beta blocker and MRA (OR=1.47, 95% CI: 0.96-2.26, p=0.07) approached but did not reach statistical significance at the p<0.05 threshold (Figure 3 ).
In contrast, the effect of different-model training did not reach statistical significance ( g = −0.37, 95%CI: −0.74 to −0.00; 95%PI: −1.18 to 0.44; p = 0.05).
Financial and Insurance Services had higher odds (OR 1.29) however did not reach statistical significance of p < 0.05.
At the protein level, BDNF exhibited a trend of upregulation consistent with mRNA changes but did not reach statistical significance. p-TrkB protein levels were reduced in CRS mice ( p < 0.05 vs. control), and BDT treatment significantly reversed this decrease ( p < 0.01 vs.
Although differences in omission errors approached the threshold, they did not reach statistical significance ( F (2,15) = 3.671, p = 0.05) and no significant differences were found for sequence errors ( F (2,15) = 1.193, p = 0.33).
did not reach statistical significancep-value < 0.05
The interaction term did not reach statistical significance (p-value < 0.05) for any of the subgroups.
In addition, epidermal consumption (p = 0.07) and increased mitotic activity (p = 0.05) were more frequent in cases with homozygous 9p21 deletion, but these differences did not reach statistical significance. When the clinical features were considered, there was a statistically significant correlation between 9p21 FISH positivity and the diameter (p < 0.05).
PD184352 treatment decreased the induction IL-10 mRNA by zymosan, while SB203580 showed a trend for a reduction in IL-10 mRNA although this did not reach statistical significance (p<0.05).
Parent-reported youth sleep improved for the entire group from pretreatment to posttreatment ( p < 0.001) but did not reach statistical significance for between-subjects analyses of the treatment group compared to the wait-list group ( p = 0.05).
For the development of CKD ≥ stage 2 alone, the difference between cats that were borderline proteinuric vs nonproteinuric at baseline approached but did not reach statistical significance (log‐rank P = .05).
However, for Nepal and Bhutan this association did not reach statistical significance (p < 0.05).
Such skewing towards overestimating the presence of X4 minority variants for these CRFs was maintained when the FPR cut-off was shifted, although these observations did not reach statistical significance using a Fisher’s exact test (p<0.05).