Barely Significant
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did not reach statistical significance

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In the literature

While combination ICI with chemotherapy showed a trend toward increased risk (HR: 1.664; 95% CI: 0.974–2.848; p = 0.063), and ICI monotherapy showed a trend toward reduced risk (HR: 0.613; 95% CI: 0.352–1.062; p = 0.082), these findings did not reach statistical significance.
For culture-proven sepsis, no significant associations were observed with biomarkers at 24 and 120 h ( p > 0.05); only CRP levels at 72 h were independently and significantly associated with culture-proven sepsis ( p = 0.049), whereas PCT levels did not reach statistical significance and showed only borderline significance ( p = 0.063) ( Table 5 ). 4.
approaching significancep=0.0641.3× alphagold
did not reach statistical significancep=0.0641.3× alphaplainly factual
Trends among individuals aged 25–34, 45–54, 55–64, and 65–74 years did not reach statistical significance although some point estimates suggested continued increase in some groups, with trends approaching significance among 45–54 (p=0.064) and 65-74 years (p=0.054).
did not reach statistical significancep = 0.0641.3× alphaplainly factual
of borderline significancep = 0.0641.3× alpha
Meanwhile, although the omega-3 group showed a lower increase in the percentage of incorporated EPA, the omega-3 group did not reach statistical significance, instead showing a trend of borderline significance ( p = 0.064).
a negative trendp = 0.0651.3× alphagold
did not reach statistical significancep = 0.0651.3× alphaplainly factual
Survival analysis revealed that high ITGAV expression was significantly associated with poor overall survival ( p = 0.031), while ITGB3 showed a negative trend that did not reach statistical significance ( p = 0.065) (Fig. 1 C–D).
did not reach statistical significanceP = 0.0651.3× alphaplainly factual
showed a trendP = 0.0651.3× alpha
Although the HAIT-M-P group showed a trend toward better OS than the HAIT group, the difference did not reach statistical significance (HR = 0.45, 95% CI: 0.19 – 1.07, P = 0.065; Figure 2D ).