Barely Significant
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did not reach statistical significance

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In the literature

HPV negativity and high abundance of B cell/CD8 + T cell interactions in the tumor nests did not reach statistical significance, but there was a strong trend ( p = 0.063, HR = 0.29, 95% CI = 0.08–1.06 and p = 0.068, HR = 0.11, 95% CI = 0.01–1.17; respectively).
approaching significancep=0.0641.3× alphagold
did not reach statistical significancep=0.0641.3× alphaplainly factual
Trends among individuals aged 25–34, 45–54, 55–64, and 65–74 years did not reach statistical significance although some point estimates suggested continued increase in some groups, with trends approaching significance among 45–54 (p=0.064) and 65-74 years (p=0.054).
did not reach statistical significancep = 0.0641.3× alphaplainly factual
of borderline significancep = 0.0641.3× alpha
Meanwhile, although the omega-3 group showed a lower increase in the percentage of incorporated EPA, the omega-3 group did not reach statistical significance, instead showing a trend of borderline significance ( p = 0.064).
There was an overall trend for an interaction of sex and generation (‘Sex*Generation’: F 2,794 = 2.761, p = 0.064) that did not reach statistical significance, and we did not detect any effect of sex or the interaction between line and sex on the time individuals spent leading.
a negative trendp = 0.0651.3× alphagold
did not reach statistical significancep = 0.0651.3× alphaplainly factual
Survival analysis revealed that high ITGAV expression was significantly associated with poor overall survival ( p = 0.031), while ITGB3 showed a negative trend that did not reach statistical significance ( p = 0.065) (Fig. 1 C–D).
did not reach statistical significanceP = 0.0651.3× alphaplainly factual
showed a trendP = 0.0651.3× alpha
Although the HAIT-M-P group showed a trend toward better OS than the HAIT group, the difference did not reach statistical significance (HR = 0.45, 95% CI: 0.19 – 1.07, P = 0.065; Figure 2D ).
did not reach statistical significancep = 0.0661.3× alphaplainly factual
showed a trendp = 0.0661.3× alpha
The presence of the HLA-A03 supertype showed a trend in association with protection against developing irAEs that did not reach statistical significance (RR = 0.35, 95%CI 0.12–0.96, p = 0.066).
a negative trendp = 0.0661.3× alphagold
did not reach statistical significancep = 0.0661.3× alphaplainly factual
Furthermore, thalamic GABA+ concentrations were significantly negatively correlated with BAI scores ( r = −0.467, p = 0.038) ( Figure 3B ), and while a negative trend with the KSS was observed, this did not reach statistical significance ( r = −0.419, p = 0.066) ( Figure 3C ).