“did not reach statistical significance”

In contrast, beta-blockers showed a trend toward a protective effect (OR: 0.47, 95% CI: 0.22–1.03, P = 0.058), though this did not reach statistical significance.

Although the difference approached significance, it did not reach statistical significance ( p = 0.058).

A notable trend was observed between the groups after the 12-week intervention period when comparing the change in area under the curve (ΔAUC) for glucose ( p = 0.058); however, this result did not reach statistical significance.

This showed a strong trend in the logistic regression model ( p = 0.058) which did not reach statistical significance possibly due to the small sample size (Type I statistical error).

Although the mediation effects for SDoH = 1 and SDoH = 2 did not reach statistical significance, it was noteworthy that the effect for SDoH = 2 approached significance for both mortality outcomes ( P = 0.058).

Although unmarried patients showed a trend toward worse DSS, this finding did not reach statistical significance (HR = 1.285, p = 0.058).

Although tumor invasion of the ventricle showed a strong trend, it did not reach statistical significance in the multivariate model (OR = 6.21, 95% CI: 0.94-41.15, P = 0.058).

Women with normal weight (18.5 ≤ BMI < 24.0 kg/m 2 ) also showed a trend toward reduced risk (OR = 0.73, 95% CI: 0.53–1.01, p = 0.058), although this did not reach statistical significance.

DAT−/− rats showed a 1.5-fold increase in the levels of ALDH1L1 (one-way ANOVA F (2, 14) = 11.79; p = 0.0010; Tukey’s multiple comparison test p = 0.0007 DAT−/− versus DAT+/+ controls), while DAT+/− rats showed a trend toward elevation that did not reach statistical significance (Tukey’s multiple comparison test p = 0.0586 DAT+/− versus DAT+/+ controls; Figure 4 A).

Glycaemia at daytime versus night‐time during the 5‐day exercise period While there was a numerical trend for more time spent in euglycaemia for the 75% IDeg dosing period during night‐time, it did not reach statistical significance ( P = 0.059; Table 3 ): 3.5.

Although post hoc comparisons did not reach statistical significance after Bonferroni correction, a clear trend toward higher TAN counts was observed in the c-erbB2-positive group compared with the c-erbB2-negative group (mean rank = 36.65 vs. 28.91, p = 0.059) ( Table 4 , Chart 4 ).

However, the difference in AST and ALP did not reach statistical significance ( p = 0.378 for AST, p = 0.190 for ALP), while GGT showed borderline significance ( p = 0.059). 3.4 WQS regression The eight components that make up the LE8 score were evaluated for their impact on these liver function parameters ( Figures 3A – E ).

The root extracts showed a trend toward increasing CASP9 expression ( p = 0.059), but this did not reach statistical significance, meaning that while there might be a potential effect, the data do not provide strong enough evidence to confirm a reliable upregulation at the tested doses.

RFDR showed a tendency toward significance (F = 2.893, p = 0.059, η 2 = 0.048) but did not reach statistical significance after adjustment.

Carer psychological distress showed a positive trend in its association with increasing PLWD unmanaged symptoms (coefficient = 0.07, 95% CI [−0.00, 0.13], p = 0.059) and agitation (coefficient = 0.06, 95% CI [−0.01, 0.14], p = 0.090), but both analyses did not reach statistical significance.

A favorable trend was also observed for overall survival (OS) (HR = 0.75, 95% CI: 0.55-1.01, P = 0.059, Figure 3F ), although this did not reach statistical significance.

While a positive trend was observed between GRS and fasting C-peptide (β = 0.0228), this association also did not reach statistical significance (p = 0.059).

IL‐10 showed a trend toward higher values in the high‐exposure group ( p = 0.0600) but did not reach statistical significance under the unpaired t ‐test.

The other interactions did not reach statistical significance despite they showed an interesting trend towards significance: gender x smoke (ß = 0.05, p = 0.06), gender x victimization (ß = 0.04, p = 0.08), and gender x body comparison (ß = 0.04, p < 0.08).

Cognitive function showed an increasing trend across CNQ tertiles, from 12.89 in the lowest group to 14.37 in the highest ( P = 0.06), although the difference did not reach statistical significance.

While fresh EVs were used as a positive control and showed a clear trend toward increased organoid formation, the differences did not reach statistical significance ( p = 0.06), likely due to the variability inherent in primary cell cultures.

In contrast, the expression level of arginase-1, an M2-type microglial marker, was significantly reduced in OBX mice, while TGF-β exhibited a decreasing trend that did not reach statistical significance ( p = 0.06; Fig. 4 J and K).

The overall pooled estimate across both time points showed a trend toward improvement that did not reach statistical significance (mean difference: 21.27, 95% CI: −0.96 to 43.50, p = 0.06), with substantial heterogeneity observed ( I 2 = 80%, p = 0.03).

A positive trend was also observed in the application of pressure after needle removal (p = 0.060), although this did not reach statistical significance.

Although there was an apparent trend for the women with a diagnosis of endometriosis to use more antidepressants, these differences did not reach statistical significance (P=0.06).