Although an increasing trend has been observed for STEP 61 expression over the course of 96 h following chronic ECS, this trend did not reach statistical significance due to a large standard deviation ( Figure 1(e) , Supplemental Figure 1).
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Although APOLD1 showed a trend towards lower OS in the high-score group, it did not reach statistical significance and was excluded ( Fig. 2 F).
a slight trendgold
Overall protein synthesis showed a slight trend for suppression, but this did not reach statistical significance (SMD -0.47, 95%CI: −1.32 to 0.39, p = 0.25). 3.3.2.
17 One study in which first-degree relatives of PD patients and controls were interviewed and screened for tremor showed a trend toward increased risk of ET among family members of patients with PD, with 4.8% of relatives of PD patients having ET versus 3.5% of controls, though this did not reach statistical significance (p = 0.08). 60 The risk increased with younger onset of PD (5.8% of relatives had ET when PD onset was ≤66 years p = 0.006) and with tremor-dominant or mixed forms of PD.
However, regarding α-diversity, our study showed a decreasing trend in gut microbial diversity in CRC patients with synchronous polyps, but it did not reach statistical significance.
Western blot analysis showed that although the phosphorylation of AMPK (p-AMPK) exhibited an increasing trend in the MG5012- and MG741-treated groups compared to the HFD group, this difference did not reach statistical significance ( Figure 4 F,I).
Rades et al [ 55 ] tested a simple reminder app for skin and mouth care during radiotherapy; while it did not reach statistical significance, it showed a trend toward fewer severe side effects.
KCC2 heterozygous mice showed a trend toward a higher seizure severity compared to the wild type strain, but it did not reach statistical significance ( z = 0.14).
Patients with genotype “ FLT3-ITD + /NPM1 - ” showed a trend of poor EFS compared with those without the cytogenetic characteristic, but it did not reach statistical significance ( P = 0.089; Fig. 1f ).
In the NFA group, GSH-Px, SOD, and T-AOC showed an increasing trend compared with the CON group, although these changes did not reach statistical significance ( P > 0.05).
Age and polypharmacy did not reach statistical significance but showed a trend toward association with the outcome.
The sacral group were strongly associated with an increased risk of in-hospital mortality (aOR 3.15, 95% CI: 1.75–5.69, p < 0.001), while the thoraco-lumbar region showed a trend toward higher mortality risk, but this did not reach statistical significance (aOR 2.62, 95% CI: 0.97–7.11, p = 0.059).
In this study, co-implantation of SC1 with U87MG cells ( Supplementary Figure S2 ) or intravenously treated U87MG tumor-bearing mice with suboptimal dose regimen of SC1 ( Figure 6A ) showed a clear trend for efficacy, although the tumor volume reduction did not reach statistical significance.
We found that (1) Chinese-English bilinguals showed a significant priming effect for congruent binomials but no facilitation for English-only binomials, (2) English–Chinese bilinguals showed a trend toward priming for congruent binomials, which did not reach statistical significance, and no priming for English-only binomials, (3) English monolinguals showed comparable priming for congruent and English-only binomials.
There was a numerical trend suggesting a possible shift in breathing route from oronasal to nasal during both phases of the study (Table 3 ); however, statistical analysis of the data from the active phase by both Wilcoxon test ( P = 0.359) and two-sample t test ( P = 0.559) showed that this trend did not reach statistical significance.
In an early exploratory analysis of RTOG 9802, the subgroup of patients with oligodendrogliomas showed the greatest benefit statistically in terms of benefit from PCV whereas the astrocytoma subgroup only showed a trend (but did not reach statistical significance).
Regarding the improvement in frailty scores, combined interventions demonstrated the greatest improvement (SMD = -0.92, 95% CI: -1.43 to -0.40), followed by multicomponent exercise (SMD = -0.78, 95% CI: -1.15 to -0.43), while nutritional supplementation showed a trend toward improvement that did not reach statistical significance (SMD = -0.69, 95% CI: -1.67 to 0.27).
The global analysis included 3905 randomized patients and showed an aggregated superior clinical success rate of moxifloxacin of 1.5% (95% CI = −0.4%–3.4%) which did not reach statistical significance, but showed a trend towards a better clinical outcome with moxifloxacin (Figure 2 ).
a positive trendgold
Sweets intake (DI_sweets) showed a positive trend toward higher distress, but did not reach statistical significance (OR = 1.33, 95% CI: 0.99–1.80, p = 0.064).
Although this finding did not reach statistical significance, a clear trend was observed.
a possible trendgold
Although the MDF difference between conditions at the mid-point did not reach statistical significance, the effect approached the threshold ( p = 0.055), suggesting a possible trend.
In our study, eyes with cluster PHS showed a trend of high prevalence of venous dilation and CVH, although the differences did not reach statistical significance.
dose, showed a trend in theta power elevation; however, this effect did not reach statistical significance in the Bonferroni post hoc comparison.
Body weight showed a trend toward reduction but did not reach statistical significance.
Our data also showed a trend towards a higher incidence of post-stroke pneumonia with higher SHR tertiles, yet this relationship did not reach statistical significance after adjustment, even though a prior study reported an independent association between SHR and post-stroke pneumonia [ 31 ].