In both studies, the negative association between HBV infection and BMD was more pronounced in men, while in women, it did not reach statistical significance and even showed a positive trend with BMD in premenopausal women ( 4 , 15 ).
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313 14 16 , 18 Although our study showed a trend favouring the combination of PPV with encircling band for repairing inferior RRD (86% success rate), this did not reach statistical significance.
The difference in PFS in this indirect comparison showed a trend favouring trabectedin, but did not reach statistical significance with a p value of 0.074.
The mRNA expression levels of Acc increased ( p = 0.074) in HFHC-fed mice compared with CD-fed mice, indicating that there might be an increasing trend that did not reach statistical significance.
The pooled SMD of 0.33 represents a small effect size according to Cohen’s conventions, suggesting a slight trend toward higher total cholesterol in the NHT group, though this did not reach statistical significance [ 11 , 51 ].
Griffith et al, 40 who performed a meta-analysis of the effect of calcium on blood pressure, found a small statistically significant effect of calcium on lowering systolic blood pressure independent of baseline blood pressure, and a small trend toward reduction in diastolic blood pressure that did not reach statistical significance.
Consensus clustering of immune cell proportions classified BCa samples into four distinct subtypes (C1-C4), with differential risk group distributions: C1 (wound healing), C3 (inflammatory), and C4 (lymphocyte-depleted) subtypes were relatively more common in low-risk cases, while the C2 (IFN-γ-dominant) subtype showed a trend toward higher prevalence in high-risk patients, though this association did not reach statistical significance (Fig. 4 E).
DSS treated Bid −/− mice showed a trend to shortened colons—consistent with increased inflammation—at the endpoint of eight days compared to WT mice, but this did not reach statistical significance ( Figure 5 c).
Living alone and higher CCI scores showed a trend toward lower postoperative M-QOL, although these did not reach statistical significance ( p = 0.058 for both) ( Table 5 ). 3.5.
In an additional dataset ( GSE53625 ), the high-expression group also displayed similar trends, with a decreasing trend in immune scores, although this did not reach statistical significance (P = 0.1).
Sex differences did not reach statistical significance in maze A, B and C, but showed a marginal significance in maze S and R, where males performed better than females across trips.
a negative trendgold
Umbilical artery pH demonstrated a negative trend with increasing sFlt-1/PlGF values; however, this association did not reach statistical significance after adjustment (estimated change −0.0076 per doubling; p = 0.070).
However, in their meta-analysis, the results showed that combined mortality had a favorable trend but did not reach statistical significance ( P = 0.064), which included one trial in common with our analysis[ 19 ].
Although screening ALP levels showed a trend toward elevation in osteopenic infants, the difference did not reach statistical significance.
Bioinformatic analysis of The Cancer Genome Atlas (TCGA) database revealed that elevated NSUN2 hyper-expression showed a trend toward unfavorable prognosis, 26 although this association did not reach statistical significance ( P = 0.078) ( Fig. 3 C).
C3/C4 ratio showed a trend but did not reach statistical significance (HR = 0.989, p = 0.955), explained by collinearity with eGFR (Spearman r = 0.339, p = 0.0002) ( Table 6 ).
Oxidised LDL levels showed a slight trend towards an increase, but differences did not reach statistical significance.
There was, however, a weak trend towards increased frequencies and absolute counts of circulating T tm subset in CD4 + T cells in the meth user group but this did not reach statistical significance ( p < 0.1 in both cases).
Although extraction cases showed a trend toward greater resorption, this association did not reach statistical significance after adjustment, suggesting that treatment duration and force characteristics may play a more critical role than extraction status alone.
The 5-year disease-free survival showed a trend in favour of Textbook Outcome; however, this did not reach statistical significance (85% vs. 75%, p = 0.33) ( Figure 2 ). 4.
Further analysis of the individual lesions showed a trend towards a higher level of tumor heterogeneity, as measured by K app , in the pseudoprogressive lesions throughout the first 12 weeks of treatment (baseline: 0.84; 3 weeks: 0.64; 12 weeks: 0.76) compared with the responding lesions (baseline: 0.59; 3 weeks: 0.54; 12 weeks: 0.56); although this did not reach statistical significance, it may reflect underlying immune cell infiltration or cell death over the course of treatment.
spiramycin to reduce placental transmission of toxoplasmosis and showed a trend toward lower transmission with PY/SA, although it did not reach statistical significance, possibly because of a lack of statistical power [ 70 ].
Offspring brain mtDNAcn showed a negative trend but did not reach statistical significance.
Prior DAIR showed a trend toward lower failure rates but did not reach statistical significance (HR = 0.043, 95% CI: 0.002–1.039, p = 0.053).
HFNC use showed a trend toward reduced MV requirement but did not reach statistical significance (OR 0.445, 95% CI 0.187–1.055; p = 0.066).