Barely Significant
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did not reach statistical significance

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In the literature

While the low dose (0.27 g kg −1 ) effectively decreased the TNF‐α level (66.13 ± 15.93 pg mL −1 , p = 0.0005, Cohen's d = 1.88), its effect on IL‐6 reduction (4.51 ± 0.27, p = 0.058, Cohen's d = 0.91) showed a strong trend but did not reach statistical significance.
did not reach statistical significanceP = 0.4799.6× alphaplainly factual
Conversely, when αβ + DNT cells were expressed as an absolute cell count, they showed a trend of a negative correlation with pediatric SLE Disease Activity Index (pSLEDAI), though this did not reach statistical significance either ( r = − 0.523, P = 0.479), likely due to the small sample size.
The addition of pembrolizumab was associated with a favorable trend toward improved event-free survival versus placebo plus CRT, but the difference did not reach statistical significance in the ITT population (the 24-month event-free survival rate was 63.2% for the pembrolizumab arm versus 56.2% in the placebo arm). 62 Currently, several clinical trials are exploring the role of different ICIs in LACC setting ( Table 1 ).
Advances in immunotherapy for cervical cancer.
Ther Adv Med Oncol · 2023 · PMC10052578