Both miRNAs showed a trend towards positive correlation with pre-operative serum PSA levels, but this did not reach statistical significance.
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The 5-year disease-free survival showed a trend in favour of Textbook Outcome; however, this did not reach statistical significance (85% vs. 75%, p = 0.33) ( Figure 2 ). 4.
Other features showed a trend toward the predicted direction but did not reach statistical significance using a conservative bootstrapping technique.
The highest levels of iNOS showed a trend towards decreased recurrence free survival but did not reach statistical significance (p=0.156).
There was an overall trend toward a higher percentage of patients reaching the primary end points in the CEST group, but the differences did not reach statistical significance.
The complex I activity in Cdkl5 +/− heart mitochondria showed a trend of reduction compared to controls, although it did not reach statistical significance ( Figure 5 D).
In a follow-up study by Dreyer et al., the same techniques found a favorable trend in ICP, CPP, and patient outcomes in the OMT cohort; however, they did not reach statistical significance [ 20 ].
Having an elevated BMI showed a trend toward an association with developing postoperative infection but did not reach statistical significance (adjusted OR = 1.025, 95% CI = 0.999-1.052, P < .056).
An increasing trend in proteinuria with higher sodium intake was observed in individuals with diabetes, although this did not reach statistical significance ( S1A and S1B Figs ).
Correlation of megalin expression with YBX3 showed a trend to an inverse relationship but did not reach statistical significance (Additional file 1 ).
The trabecular separation displayed a decreasing trend in the CDH-13-treated group, but the difference did not reach statistical significance ( Figure 5J ).
The glucose metabolism of the sham group showed a trend of increase in the S1ULp, S1BF and S2 after GBP treatment, although the changes did not reach statistical significance.
The relative permeability of TSC2 mutant BMEC barriers showed a trend towards higher permeability than barriers from control BMECs for the 3 kDa dextran, but the difference did not reach statistical significance (Fig. 2 A).
Lobule V showed a trend towards smaller volume in CD patients, but the result did not reach statistical significance ( p = 0.082).
Mice in dose group 3 showed a trend toward increased IL-17A, although this did not reach statistical significance.
While the low dose (0.27 g kg −1 ) effectively decreased the TNF‐α level (66.13 ± 15.93 pg mL −1 , p = 0.0005, Cohen's d = 1.88), its effect on IL‐6 reduction (4.51 ± 0.27, p = 0.058, Cohen's d = 0.91) showed a strong trend but did not reach statistical significance.
The PLR showed a trend but did not reach statistical significance (135.7±52.9 vs. 120.2±43.4; p=0.058).
Conversely, when αβ + DNT cells were expressed as an absolute cell count, they showed a trend of a negative correlation with pediatric SLE Disease Activity Index (pSLEDAI), though this did not reach statistical significance either ( r = − 0.523, P = 0.479), likely due to the small sample size.
The CDVA, PROS, FOSPET and FPR showed a trend toward progressive decline when analyzed across pedigree subgroups with simplex or sporadic cases being the best and X-linked, the worst (Table 3 ); however, apart from PROS, the differences did not reach statistical significance.
Results We observed a negative trend in alpha diversity with time in residence at the LRC; nevertheless, the patterns did not reach statistical significance for any metric.
The thrombolysis and in-hospital mortality showed an increasing trend but did not reach statistical significance ( p = 0.07 for thrombolysis, p = 0.10 for mortality).
The addition of pembrolizumab was associated with a favorable trend toward improved event-free survival versus placebo plus CRT, but the difference did not reach statistical significance in the ITT population (the 24-month event-free survival rate was 63.2% for the pembrolizumab arm versus 56.2% in the placebo arm). 62 Currently, several clinical trials are exploring the role of different ICIs in LACC setting ( Table 1 ).
Age showed a borderline association with post-treatment hypothyroidism (adjusted OR = 0.962; p = 0.063), suggesting a possible trend toward lower odds with increasing age, although this did not reach statistical significance.
The cCMV group also showed a trend toward more specific clonotypes than the aCMV group, but this did not reach statistical significance (P = 0.086).
In contrast, retinol intake showed a positive trend in adenoma prevalence in the high red meat group, although this did not reach statistical significance. 2.