Results We observed a negative trend in alpha diversity with time in residence at the LRC; nevertheless, the patterns did not reach statistical significance for any metric.
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In the literature
CD105 (endoglin) and TLR4 ( Li et al., 1999 ) showed a trend toward increased expression 24 hr after the fourth LPS injection ( Figure 1D ), but mean fluorescence intensities (MFIs) did not reach statistical significance.
Furthermore, this cluster (identified as “cDC1c”) showed a trend of positive Hif1a mRNA expression that did not reach statistical significance (Supporting Information: Figure S4B , Table S2 ).
Although differences did not reach statistical significance, a trend towards significance was strongest for the left and right SLF parietal sections.
ACTT-1 also showed a trend toward reducing mortality, but the difference did not reach statistical significance [3] .
The Pro58Ser/Phe178Leu variant showed a trend towards higher total protein expression level compared to Pro58Ser variant, but this did not reach statistical significance (Fig. 7 d ).
Furthermore, a recent study elucidated variables associated with COVID-19 vaccination among Israeli adolescents (n=43,919) using data from an electronic database, showing that adolescents of low SEP had a very low vaccination rate (42.3%) compared to those having a high SEP (80.4%), which was highly significant upon univariate analysis but did not reach statistical significance using a multivariate approach [ 22 ].
The absence of coronary lesions showed a trend towards a lower incidence of the primary outcome that did not reach statistical significance.
IL-6 followed an increasing trend in both the treatment and control groups, with a mean difference of 674.6 ± 838.9 pg/mL in the treated and 341.3 ± 554.5 pg/mL in controls; however, this did not reach statistical significance ( p = 0.106 in treated and p = 0.552 in controls).
In contrast, depletion of RIPK3 alone on the 5xFAD background only resulted in a slight trend toward decreased D54D2 staining in the RS; however, this did not reach statistical significance ( Figure 2, C and D ).
Similarly, by SFB, levels of antibodies binding to the surface-expressed XBB Spike showed a trend toward being higher among those who received mRNA-1273 (median 37.6% binding) relative to BNT162b2 (median 31.3% binding), though this did not reach statistical significance ( Fig. 1 C).
More prominently, patients with high Mφ density (CD68 Hi ) showed a trend towards a longer median OS compared with patients with low Mφ density (CD68 Lo ), although this did not reach statistical significance (15.0 months vs. 10.4 months, P = 0.11; Fig. 1 B).
Although differences in CEP levels between time points in peripheral blood did not reach statistical significance, a clear trend toward increased circulating levels could indicate the presence of extravasation processes of the administered CEP-DilC18s.
Although the c-MET IHC distribution pattern ( p = 0.068) and initial brain metastasis ( p = 0.061) showed a trend, the findings did not reach statistical significance.
The addition of pembrolizumab was associated with a favorable trend toward improved event-free survival versus placebo plus CRT, but the difference did not reach statistical significance in the ITT population (the 24-month event-free survival rate was 63.2% for the pembrolizumab arm versus 56.2% in the placebo arm). 62 Currently, several clinical trials are exploring the role of different ICIs in LACC setting ( Table 1 ).
As for the IPITT results, the AUC showed a decreasing trend but did not reach statistical significance in TG-treated Lv-shPKACα mice when compared with untreated Lv-shPKACα mice (Fig. 7 E).
The acquisition phase was followed by a probe trial which showed a trend for LVR to spend less time in the correct quadrant relative to WT and HVR, but this difference did not reach statistical significance {trending group main effect [ F (2, 31) = 3.237; p = 0.053] with Tukey post-hoc analysis revealing trending group differences: LVR vs.
The number of EPCs showed an increasing trend in the teneligliptin treated group; albeit this did not reach statistical significance.
During co-treatment of LPS with TMs, Cxcl10 and Il1b levels decreased in sera derived from treated mice compared to those in sera from control mice (treated with LPS+DMSO); the anti-inflammatory cytokine Il10 showed an increasing trend that did not reach statistical significance, whereas Il6 and Tnfα did not show altered levels in mouse sera ( Fig. 7 C).
In children with 22q11DS, FW span and BW span showed a trend towards a moderate correlation, but this did not reach statistical significance ( r (36) = 0.29, p = 0.083, 95% CI [− 0.04–0.57]).
Conversely, a strong trend towards a negative correlation between NDEVs’ STX-1A/VAMP-2 concentrations and RBDSQ total score was also observed, although this correlation did not reach statistical significance.
An increasing trend was found in the join point analysis, but the increase did not reach statistical significance ( P > .05).
In addition, anxiety rate showed a decreasing trend at M6 in RTC group compared with UC group, although it did not reach statistical significance.
Nonetheless, even though the results did not reach statistical significance, there was a positive trend observed.
Our analyses between CE-ASPECTS and sICH did not reach statistical significance, though a trend towards significance may have been present.