Weight Our pooled studies at endpoints showed a trend towards higher weight with lifestyle interventions plus metformin; however, this did not reach statistical significance (SMD = 0.12, 95% CI [-0.03, 0.27], P = 0.11).
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In contrast, the prevalence of MUO showed a decreasing trend among women in all age groups, although it did not reach statistical significance ( Table 1 ).
Tumor-related factors: Tumor ulceration and necrosis showed a trend toward worse survival but did not reach statistical significance (HR = 0.52 for absence vs. presence; 95% CI: 0.23–1.16 and p = 0.112).
Additionally, the triple combination showed a trend to improved survival beyond that induced by any two combinations of pSP-D-CD40L, CpG or poly(I:C), although this did not reach statistical significance in the small number of animals used in this study ( Fig. 3F , n = 5/group).
Although reductions in total serum IgE did not reach statistical significance, XG + CWMT showed a favorable trend, suggesting potential immunomodulatory effects.
After adjustment, all variables showed a trend towards association with the development of SIRS but did not reach statistical significance (See Supplementary Table S1 ). 3.4.
Results In the adjusted model, physical activity showed a negative trend with depression, though this association did not reach statistical significance in the fully adjusted model.
Notably, Pdgfd -/- mice showed a trend towards smaller islets, although the differences did not reach statistical significance (p = 0.21) due to large standard deviations ( Fig 7J ).
IgG and IgA responses to AD‐2 showed a trend towards boosting (Figure 3A ) but did not reach statistical significance.
Although some univariate Cox hazard results of lipid factors did not reach statistical significance, we saw a clear trend and called the result promising and worth further studies.
Other interventions—including propofol (MD = −2.1, 95% CrI: −4.3 to 0.082), pethidine plus sedatives (MD = −1.7, 95% CrI: −3.7 to 0.43), and fentanyl plus sedatives (MD = −1.4, 95% CrI: −3.3 to 0.49)—showed a trend toward pain relief, though these results did not reach statistical significance ( Table 1 ).
Older participants showed a trend of performing better than younger participants (YA: mean ± SD = 80.8 ± 7.9%, OA: 85.1% ± 6.5%), but this difference did not reach statistical significance ( z = –1.8, p = 0.07, Mann–Whitney U -test).
Finally, restoring ETC function with succinate showed a trend for decreased mitochondrial oxidative stress in toxin-treated SN neurons, but the effect did not reach statistical significance ( Fig. 7 B ).
Decreased ALDH1L1 expression showed a trend toward increased lymph node metastasis, although this association did not reach statistical significance (p=0.0692).
Contrarily, age showed a trend toward a hazard ratio of 1.18 for each additional year of age, although it did not reach statistical significance ( p = 0.115).
Although an overall trend of reduced locomotion was observed across all parameters, the difference between tdp1 −/− fish and their wild-type siblings in low speed count, medium speed, high speed duration and count, total distance traveled, and average speed did not reach statistical significance ( Fig. 3 and fig.
SIN-low dose showed a trend towards improvement but did not reach statistical significance ( p = 0.059).
However, while their conclusions suggested a benefit of HBO, their pooled analyses did not reach statistical significance, indicating only a nonsignificant trend.
Table 2 ), but not the association with the diagnosis; even though EMMs calculated for the factor time*diagnosis showed a trend, they did not reach statistical significance (Supplem.
Effect of Hypobaric Perfusion on Prevention of Congestion, Edema, and IR Injury Following Ex Vivo Whole-blood Perfusion Ex vivo perfusion with autologous porcine blood after 3 h of static cold storage showed a trend toward a decreased maximal arterial pressure and increased maximal blood flow in the hypobaric perfusion group, although this difference did not reach statistical significance (Figure 3 A and B).
There was an increasing trend of RHAMM expression in NSCLC with regional nodal spread compared to those that were node negative, although it did not reach statistical significance.
spiramycin to reduce placental transmission of toxoplasmosis and showed a trend toward lower transmission with PY/SA, although it did not reach statistical significance, possibly because of a lack of statistical power [ 70 ].
While a direct comparison between isotype and anti-IFNγ treated mice inoculated with BCG prior to viral challenge did not reach statistical significance, animals treated with anti-IFNγ showed a clear trend towards more severe disease and higher viral loads (Fig. 2F, G ).
Local accumulations of the cytoskeletal protein neurofilament L in axonal swellings showed a trend towards being more frequent in of KIF5A –/– motor neurons (12.4 ± 5.1 % of cells), in comparison to KIF5A +/– (9.3 ± 1.0 % of cells), and KIF5A +/+ (4.3 ± 4.0 % of cells) motor neurons, but the difference did not reach statistical significance (Fig. 2 ).
The scatter plot showed a negative trend between NEDD4 and PTEN expression, although this association did not reach statistical significance (Figure 4 G).