The effect was dose-dependent; treatment with lower doses of Rac1 peptide showed a trend toward improvement, and this trend did not reach statistical significance (Figure 2a, b ).
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Latent VZV load had an increasing trend according to age, but this trend did not reach statistical significance.
a possible trendgold
Although the differences did not reach statistical significance, the higher maximum temperature ( P = 0.059) and relative humidity ( P = 0.499) observed in 2023 suggest a possible trend toward climatic conditions conducive to dengue transmission.
Although Hispanic patients also showed a trend toward lower rates of IP arthroplasty, this finding did not reach statistical significance (OR, 0.83; 95% CI, 0.61–1.13).
Although differences in CEP levels between time points in peripheral blood did not reach statistical significance, a clear trend toward increased circulating levels could indicate the presence of extravasation processes of the administered CEP-DilC18s.
While the difference in the duration of illness approached significance, it did not reach statistical significance.
Emotional items, while scoring lower overall, showed a trend of being higher in patients with peri‐implantitis, even though this difference did not reach statistical significance.
a positive trendgold
The association with contraceptive use showed a positive trend but did not reach statistical significance after adjustment (adjusted OR = 3.22, 95% CI: 0.94–11.04, p = 0.063) (Table 8 ). 3.10.
The number of neurons positive for Kiss1 mRNA in the AVPV of female hpg mice was significantly lower than in WT females (24.7±1.2 neurons/section; P<0.001; Neuman-Keuls post-hoc), whereas the number in the hpg males (17.1±2.9 neurons/section) showed a trend towards an increase compared to WT males but did not reach statistical significance (P = 0.057; Mann-Whitney) ( Fig. 2B ) .
While these changes did not reach statistical significance, they demonstrate a positive trend following low-cost interventions.
Patients in the high risk arm with large localized tumors showed a trend toward improvement with the addition of etoposide, but this trend did not reach statistical significance [ 132 , 133 ].
Whereas yeast strains mutated in UBC12 and PAS3 showed a trend for extended lifespan, this did not reach statistical significance.
This showed a numerical trend favoring panitumumab that did not reach statistical significance [ 6 ].
Similarly, biologic therapy in the severe asthma subgroup showed a trend towards increased remission, but this did not reach statistical significance ( Fig. 2 A).
Relative to the vehicle control, RAGE mRNA expression showed a trend to be reduced by A β 1-42, but did not reach statistical significance.
Bivariate models showed a trend towards lower PTPS scores among patients who reported opioid analgesic misuse although the effect did not reach statistical significance.
On the other hand, subjects with high HDL levels but with MS showed a trend versus lower DEPCyMCase activity compared to those with high HDL levels and without MS, even if this difference did not reach statistical significance.
a positive trendgold
Accuracy improvements showed a positive trend, though they did not reach statistical significance (Stage 1 vs. 3: p = 0.070; Stage 2 vs. 3: p = 0.180, McNemar’s test).
While dialysis vintage showed a trend toward increased CI with longer duration (88.9% in patients on dialysis for more than 72 months vs 69.8% in those on dialysis for less than 24 months), this association did not reach statistical significance (χ2 = 2.38, df = 2, p > 0.05).
Although the difference did not reach statistical significance, there was a clear trend towards a more potent anti-tumor effect when propranolol was combined with chemotherapy, as compared with chemotherapy alone.
Ntrk2 and Stat3 showed a trend toward up-regulation, however these differences did not reach statistical significance (p = 0.07 and p = 0.17, respectively).
In the SMG versus NG comparison, the KEGG oxidative phosphorylation pathway (mmu00190) also showed enrichment (NES = 1.56, p = 0.003), though this did not reach statistical significance after FDR correction (FDR = 0.468), suggesting a possible trend toward increased oxidative metabolism.
However, it could not be determined whether this was due to changes in interneurons located in the stratum oriens (Or) or pyramidale (Pyr) as the densities in those subregions showed a trend but did not reach statistical significance ( Fig. 1C ).
Although the amount of Homer1 within microglial lysosomes, representing engulfed excitatory synapses, showed a trend towards increase, it did not reach statistical significance.
Although there was a slight trend towards higher EDSS values in seropositive patients compared to seronegative patients (5 vs 4), the difference did not reach statistical significance.