Patients in the high risk arm with large localized tumors showed a trend toward improvement with the addition of etoposide, but this trend did not reach statistical significance [ 132 , 133 ].
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Although these differences did not reach statistical significance, likely due to the limited sample size, an interesting trend emerged, suggesting possible nonlinear dynamics of DHEA-S across age groups in AD.
In stratified analyses, patients with wider baseline QRS duration and female sex showed a numerical trend toward greater benefit with the AP strategy, although these findings did not reach statistical significance and should be interpreted cautiously.
Although a decreasing trend was observed for other side effects, these differences did not reach statistical significance ( Table 4 ).
a possible trendgold
Although the association between age and tumor grade did not reach statistical significance ( p =0.051), the result was marginal and suggested a possible trend that may reach significance in larger studies.
Although a decreasing trend was also observed throughout the entire time course also for LCAT, particularly at the 4-hour mark, this trend did not reach statistical significance (data not shown).
There was also a clear trend for more IFN-γ in the serum for animals that were infected with the wild type, although this did not reach statistical significance ( Fig. 4 A ).
Although changes in methionine levels did not reach statistical significance, they show a definite trend of depletion.
Flow cytometry for polyploidy showed a trend for more >4 n cells in Ercc1 Δ /− organoids, however, increased DNA content did not reach statistical significance (Figure S6 E).
Furthermore, our data showed a trend toward higher serum 1,25(OH) 2 D 3 concentrations in the suboptimal and optimal groups compared with the deficiency group, although this difference did not reach statistical significance.
An increasing trend was found in the join point analysis, but the increase did not reach statistical significance ( P > .05).
For serum total P1NP, the group-by-time interaction also did not reach statistical significance but showed a trend toward a greater increase over time in the H/M/LDA than in the Remission group (Table 2 ). 4.4.
Although performance scores showed a trend towards improvement, this difference did not reach statistical significance, suggesting that both methods provided comparable levels of perceived task accomplishment and indicating that the reduction in workload did not compromise planning quality.
The annual prevalence increased from 0.9% in 2018 to 4.8% in 2024, suggesting an increasing trend over time, although the linear‐by‐linear association did not reach statistical significance ( p = 0.051).
Although the differences did not reach statistical significance for hexanoic acid, isovaleric acid, and acetic acid, an increasing trend was observed.
While this parameter did not reach statistical significance in our analysis, the p value of 0.053 indicates a possible trend toward association that may become clearer with a larger sample size.
an overall trendgold
While Figure 3B illustrates an overall trend for participants to reduce the time spent fixating the second target during CMP and Threat, the main effect of Condition on the overall percentage of time spent fixating the second target did not reach statistical significance ( χ 2 (2) = 4.97, p = .08).
Although the 3D group showed a trend toward shorter WIT, the difference did not reach statistical significance in this series.
CD105 (endoglin) and TLR4 ( Li et al., 1999 ) showed a trend toward increased expression 24 hr after the fourth LPS injection ( Figure 1D ), but mean fluorescence intensities (MFIs) did not reach statistical significance.
The age distribution showed an increasing trend in vaccination rates with age (21.3% in individuals aged ≥60 years), although this did not reach statistical significance (p = 0.104).
Compared to the ICL group, the PSS group showed a trend toward reduced microbial diversity; however, this difference did not reach statistical significance (Shannon index: p = 0.065; Simpson index: p = 0.066).
Interestingly, low-to-moderate sports injury prevention knowledge showed a trend toward higher injury odds, though this did not reach statistical significance ( p = 0.072).
Additionally, patients who received radiotherapy at multiple sites showed a trend to have improved OS compared to those who received radiotherapy at a single site, although the difference did not reach statistical significance.
In the deep brain regions, where IT delivery has struggled to demonstrate significant RNA KD in other large animal models, 9 , 11 ICV delivery resulted in significantly enhanced KD in the caudate and showed a trend toward more KD in the thalamus that did not reach statistical significance ( Figure 7 B).
Interestingly, C20:1n-9 showed a trend toward being more abundant in the hind limb muscle of males, although this did not reach statistical significance ( p = 0.074), as well as C10:0 and C12:0 ( p = 0.060 and 0.087, respectively).