“did not reach statistical significance”

Although most of the combination therapy showed a trend toward decreased incidence of severe exacerbations, the difference did not reach statistical significance.

During the water maze test, the treated APP/PS1 mice performed better, while rTg4510 mice showed a trend toward improved learning ability during training, although this improvement did not reach statistical significance, which might be caused by significant neuronal loss and hippocampal atrophy in rTg4510 mice at early adulthood, with BDNF administration could only partially improve spatial memory.

Notably, FH patients with Lp(a) > 50 mg/dL showed a trend toward higher 5-year CVD risk scores, although this did not reach statistical significance In addition, a positive association has been reported between CCS and Lp(a) in population studies among people who have not yet developed a coronary event [24] .

Although the results of the present phase 1 study showed a trend toward greater improvement in clinical parameters in the NAC group, these differences did not reach statistical significance.

Although some markers did not reach statistical significance, SOF10 showed a trend toward suppressing TGF-β downstream targets Serpine1 , Col1a1 , and Col3a1 (Fig. 3d ).

Functionally, there was a marked increase in the proportion of IFN-γ + CD8 + T cells in combinational therapy, and the proportion of TNF-α + CD8 + T cells an increasing trend, although it did not reach statistical significance (Fig. 4 I, J).

Among participants with MCI, MMSE scores showed a trend toward improvement but did not reach statistical significance (MD = 0.32, 95% CI: 0.17 to 0.48, p = 0.195), and heterogeneity remained high ( I 2 = 58.3%, p = 0.091).

Although the TT genotype did not reach statistical significance, a clear trend toward increased risk was observed.

T3 tumours showed a trend towards greater odds of TNT receipt, but this did not reach statistical significance.

showed a trend in favor of the stapler-closure technique, although it did not reach statistical significance [ 29 ].

The miRNAs bta-miR-2284y and bta-miR-2285e in the cellular fraction showed a trend towards lower levels in milk from extensive production, but the differences did not reach statistical significance. 3.3.

Higher QCE values also showed a positive trend toward greater arm pain reduction; however, this association did not reach statistical significance.

The number of copies of HAdV and ALT values showed a trend to higher values, but those data did not reach statistical significance ( Table 5 ).

Microhardness showed an increasing trend with higher BA concentrations but did not reach statistical significance ( p > 0.05).

ACE2KO mice had a small trend toward higher systolic blood pressures compared to their wild‐type littermates; however, it did not reach statistical significance (24‐h mean systolic blood pressures: ACE2 KO 117.13 ± 3 vs.

However, the effect of miR-195-5p on CPNE1 expression did not reach statistical significance and it just showed a trend toward significance based on the Linkedomics public dataset (Figure 4 D).

Further, miR‐579‐3p showed a trend for an interindividual difference from the first to the second biopsy in patients with HCC compared to the cirrhosis cohort, although it did not reach statistical significance (most likely due to a small sample size) (Fig. 2D ).

In one experiment (data not shown), the mice receiving the combined formulation showed a trend for a decrease in plasma total cholesterol compared with the mice receiving the single agents, but the difference did not reach statistical significance.

In patients who developed nephrotoxicity, there was an approximately 3-fold risk reduction in the risk of death, which did not reach statistical significance but showed a positive trend.

The results also showed a trend to less damage in parp-1 o/o mice (Figures 3 and 5 ), although, again, the difference did not reach statistical significance ( p = 0.053, by 1-way MANCOVA fixed effects test).

In contrast, handgrip strength did not reach statistical significance, although a positive trend was reported.

Women showed a trend towards higher activation of prefrontal regions when in their midluteal phase, which did not reach statistical significance (Fig. 1 ).

Although administration on D1 showed a trend of increased motility, it did not reach statistical significance.

In our cohort, pCR showed a trend toward improved RFS, although the difference in OS did not reach statistical significance, likely due to limited follow‐up and a low event rate.

As EQ-5D score, Borg dyspnoea score and LPH score came after time to clinical worsening (which did not reach statistical significance) in the hierarchy these analyses can only be considered exploratory and nominally significant.