“did not reach statistical significance”

Although many of the genes comprising these sets did not reach statistical significance individually, taken as a group they were highly significant.

The inhibitory effect of the Rho kinase inhibitor Y27632 and the L-type calcium channel blocker nifedipine on ceramide-induced contraction did not reach statistical significance, but the effects of both drugs combined were highly significant ( Figure 4 D ). 3.5 Hypoxic K V channel inhibition As expected, 1 , 2 we found that hypoxia inhibited K V currents ( Figure 5 ) with a similar time course to the hypoxia-induced ceramide production and contraction.

Younger age as a prognostic factor did show a trend towards improved local and regional control which did not reach statistical significance (borderline significant p values).

There was also a strong trend for putatively tolerant children to be more susceptible to malaria compared to the exposed sensitized children, although this relationship did not reach statistical significance.

20 52 Nevertheless, while the ultrasound-based model showed a trend for a better association with enthesophytes compared with DEI, this difference did not reach statistical significance.

SIBO was significantly more frequent in patients with partial resection of the colon or multiple intestinal surgeries; there was also a clear trend in patients with ileocecal resection that did not reach statistical significance.

There was a slight trend for a higher age among patients who died, even though it did not reach statistical significance.

In addition, although the differences between uTWEAK levels at flare and at ± 2 months did not reach statistical significance, a clear trend in a similar direction is observed.

Although both showed a trend for improvement in walk time, P-value did not reach statistical significance in one study [ 19 ] and was not reported in the other [ 16 ].

The effect was dose-dependent; treatment with lower doses of Rac1 peptide showed a trend toward improvement, and this trend did not reach statistical significance (Figure 2a, b ).

EQ-5D-3L There was an overall trend of improving scores in the Euro-QoL visual analogue scale from T1 to T2 and from T1 to T3, however, this did not reach statistical significance ( Table 2 ).

The mean AET decreased significantly by 2.39%, and the DeMeester score showed a trend toward improvement, even though it did not reach statistical significance [ 72 ].

In CFA3D, PRE-084 showed a trend toward hyperpolarizing the threshold, although this effect did not reach statistical significance ( p = 0.09, Figure 6 C).

Although differences in CEP levels between time points in peripheral blood did not reach statistical significance, a clear trend toward increased circulating levels could indicate the presence of extravasation processes of the administered CEP-DilC18s.

On parallel both groups of male 3xTg-AD mice showed a trend to impaired glucose tolerance albeit it did not reach statistical significance. 3.3.

In the BAL from LPS-challenged mice, treatment with ACT-1004-1239 significantly reduced LPS-induced CXCR3 + lymphoid cell recruitment ( Figure 3C ) and showed a trend to decrease the late recruitment of the few CXCR3 + myeloid cells induced by LPS, although this did not reach statistical significance ( Figure 3D ).

While continued anticoagulation showed a trend toward lower stroke risk, this difference did not reach statistical significance.

Whereas yeast strains mutated in UBC12 and PAS3 showed a trend for extended lifespan, this did not reach statistical significance.

2 E), the positive associations did not reach statistical significance but showed a suggestive trend.

Two studies showed a trend in cardiac [ 32 ] and all-cause (GIPS) mortality in favour of GIK, though these did not reach statistical significance.

Delayed Graft Function (DGF) Our primary marginal-matched analysis revealed a small trend for a lower DGF-rate of 9.2% in the HMP group versus 16.1% in the SCS group ( Table 4 ); however, the difference did not reach statistical significance (mean difference: −6.9 [−14.1; 0.4], p = 0.063).

The study showed a trend toward higher composite all-cause mortality and amputations in the paclitaxel DCB group compared with PTA but this difference did not reach statistical significance (35.2 vs. 25.2%, P = 0.064).

Griffith et al, 40 who performed a meta-analysis of the effect of calcium on blood pressure, found a small statistically significant effect of calcium on lowering systolic blood pressure independent of baseline blood pressure, and a small trend toward reduction in diastolic blood pressure that did not reach statistical significance.

PET-assisted decision-making compared to standard care showed a trend but did not reach statistical significance with respect to the primary composite end point (cardiac death, myocardial infarction, or recurrent hospital admission for cardiac causes).

Elevated hs-CRP levels showed a trend towards poorer cognition in individuals experiencing SCD, though this did not reach statistical significance ( Zhang et al., 2023 ).