mRNA Expressions of Human Nucleus Pulposus Cells Treated With C/G/GP Hydrogel Containing LVS‐NPs After 24 h of treatment, the human nucleus pulposus cells treated with 5 μM lovastatin (group L) showed a trend toward higher mRNA expression of ACAN , DCN , and SOX9 compared with the other groups, although the difference did not reach statistical significance ( p ‐value = 0.081, 0.070, and 0.092, respectively; Figure 5A ).
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In an additional dataset ( GSE53625 ), the high-expression group also displayed similar trends, with a decreasing trend in immune scores, although this did not reach statistical significance (P = 0.1).
Although an increased age, particularly beyond 51 years, showed a trend toward reduced engagement in PA in our study population, it did not reach statistical significance.
a negative trendgold
Diabetes duration showed a negative trend (β = −2.74), suggesting that efficacy may decrease by approximately 2.7% for each additional year of disease duration, although this did not reach statistical significance in the multivariate model ( p = 0.085).
After Vit-D supplementation, we noticed a decreasing trend in iPTH levels at the 6-month follow-up; however, it did not reach statistical significance ( Table 2 ).
Only the L/O ratio showed a trend toward higher values in the V-shape group, but this did not reach statistical significance.
Although the probiotic group showed a trend towards reduced plasma CRP-levels, this effect did not reach statistical significance.
For the OS, a PR-positive status showed a trend toward reduced mortality risk compared with the PR-negative patients (HR, 0.61; 95% CI, 0.30–1.24), though this did not reach statistical significance ( p = 0.173).
Although f__Lachnospiraceae showed a positive trend with small intestine D2cc, this correlation did not reach statistical significance.
Even after adjusting for potential confounders, HBOT showed a favorable trend (OR = 2.32), although it did not reach statistical significance.
a positive trendgold
Filter used for "age at marriage" produced a large number of false positive and displayed a positive trend but did not reach statistical significance (15/424 vs. 5/336 p = 0.080).
In the PFS analysis, patients with a history of liver resection showed a trend toward improved PFS, although this did not reach statistical significance (P<0.10).
In contrast, siRNA-mediated STRIP1 knockdown showed a trend toward increased expression of hypertrophic marker genes compared to control siRNA, both under basal conditions and following PE or ISO stimulation, although these changes did not reach statistical significance ( Supplementary Figure S3 ).
Although an increasing trend can be observed in DRD1 and DRD2, it did not reach statistical significance.
AZD8848 showed a trend towards decreased maximal LAR fall in FEV 1 versus placebo at 1 week after dosing, but this reduction did not reach statistical significance (18% decrease vs placebo; p = 0.076).
There was a slight trend toward more dead cells with 1% oxygen treatment, but this did not reach statistical significance ( Fig. 3 ).
The faces scale, a subset of the BRWP, showed a trend toward benefit but did not reach statistical significance (p=0.085).
Although the groups treated with KA at 1 and 10 mg/kg showed a trend toward improvement in both tests, these changes did not reach statistical significance compared to the model group ( Figure 2 ).
Expression of the macrophage-associated chemokine Ccl2 was increased, while Ccl3 showed an increasing trend that did not reach statistical significance, and the corresponding receptor Ccr2 was reduced in Mpc2 CKO lungs (Figure S1 B).
Compared with nonsurviving infants, surviving ILWH showed a trend for higher C5-specific binding activity measured by ELISA , although this difference did not reach statistical significance ( P = .07) ( Figure 2 A ).
Although these findings did not reach statistical significance ( p = 0.088), a decreasing trend in risk with increasing zinc intake was noted.
Caregiver sex showed a trend toward a higher prevalence of moderate-to-severe burden, although the association did not reach statistical significance ( Table 3 ).
Although the θ and α effects during the N1 window did not reach statistical significance, both bands showed a trend toward increased modulation.
However, these recommendations were based mainly on 3 studies: a single randomized trial [ 22 ] which had a high risk of bias by the Cochrane risk assessment tool; a meta-analysis by Berger et al [ 7 ] that showed a trend of reduction in the composite of MI, nonfatal stroke, and cardiovascular death with aspirin that did not reach statistical significance; together with older evidence from the Antithrombotic Trialists’ Collaboration (ATC) meta-analysis [ 4 ].
Sex differences did not reach statistical significance in maze A, B and C, but showed a marginal significance in maze S and R, where males performed better than females across trips.