“highly significant”

The difference at each corresponding dose was highly significant ( P < 0.002).

Overall, 29/149 (19.5%) patients responded with ≥75% seizure suppression in the non-SV2A group compared with 14/175 (8%) patients in the SV2A group, a highly significant difference ( P = 0.0020; Fisher’s exact test).

The interactions between the two gene modifications were also highly significant for both brain regions (p = 0.002 for hippocampus, and p = 0.005 for cortex).

Some values were highly significant ( P < 0.002, after Bonferroni correction), showing the existence of genetic differentiation among the samples analyzed (Table 5 ).

This model revealed a highly significant result explaining 50% of measured functional connectivity (R2 = 0.50; adjusted R2 = 0.42, F-value = 5.9; P = 0.002).

Moran’s I on the OLS residuals decreased monotonically with distance (0.21 at 100 km → 0.09 at 200 km), but remained positive and highly significant for all thresholds tested ( p ≤ 0.002), indicating persistent spatial autocorrelation in the residuals regardless of the specific choice of d.

Importantly, there were highly significant spatial attention × hemisphere interactions (P1: F (1,28) = 11.89, p = .002, η 2 p = 0.30; N1: F (1,28) = 30.13, p <.0001, η 2 p = 0.52), which resulted from both the P1 and N1 amplitudes being significantly larger in response to spatially attended than unattended visual

There is a statistically highly significant difference ( P < 0.002) between normal and early gastric cancer.

Results: There was a highly significant association between higher Beclin1 and LC3B immunoreactivity score and Gleason score (score 8 and 9) ( P =0.002 and 0.000, respectively).

McNemar χ 2 tests for the insusceptible category between the two tests yielded highly significant results for ceftriaxone (χ 2 =9.25, P =0.002) and cefixime (χ 2 =17.49, P =0).

The increase in ELISPOT response at one week was highly significant for Ag85A peptides (p = 0.002), Ag85A protein (p = 0.004), and PPD-T (p<0.001).

For these 21 miRNAs, all data from stage I and stage II were merged and analyzed together resulting in highly significant DEG that survived Bonferroni correction for multiple comparisons (p < 0.002 [0.05/21]) and ROC between 0.9–1.0 were calculated for most genes suggesting a complete or almost complete separation of gene expression relative to the pre-exposure reference (bold p-values, Supplement Table 2 , right part).

When considering the overall miRNA expression ( miRNA Sum ), the difference between healthy controls and ccRCC patients remained highly significant (U = 452.5, Z = −3.157, p = 0.002), confirming a distinct urinary miRNA signature associated with ccRCC ( Table 2 ).

In the sub-sample of 17 No-SCD participants that were matched to the SCD group, the difference in FRN amplitude between positive and negative feedback was still highly significant, t (16) = 3.80, p = 0.002, d = 0.92.

MMRR analysis resulted in a highly significant correlation between F ST and the climatic distance matrix ( R = 0.34, p = 0.002), while the contribution of geographic distance to genetic differentiation was non-significant, only if evaluated with altitudinal distance (Table 3 ).

The effect of DNMT3A genotype on birth weight and DNMT3B on length of gestation were the least significant before the exclusion and just below significance following the reduction in numbers; though the stronger DNMT3B effect on risk of prematurity remained highly significant (p = 0.002) after exclusion of the non-Caucasian pregnancies.

However, there is a highly significant difference in median Θ values between the cancer group (167 individuals) and the the normal mucosa group (45 individuals) ( p < 0.002) ( Fig 3D ).

Moderately differentiated and PD tumours themselves form weaker clusters ( P =0.05 and P =0.06, respectively), however when combined they show a highly significant clustering pattern ( P =0.002).

Under the accommodative stimulus of − 5.0 D, the effective strain exhibited a highly significant graded attenuation among groups: CN (0.28 ± 0.06) > HM (0.20 ± 0.03) > Elderly (0.16 ± 0.05) ( P = 0.002).

Expression differences between polygyne workers of different Gp-9 genotype ( BB , Bb ) were confirmed to be highly significant for all 39 genes identified by the ANOVA (all P <0.002), as were expression differences between BB workers of different social form for all 91 genes identified by the ANOVA (all P <0.002).

Postoperative radiochemotherapy was highly significant associated with development of LEL ( p = 0.002).

The correlation between ash content and N 2 O emissions was highly significant (r 2 = 0.809; P = 0.002).

When comparing the number of poor sleepers in the different subgroups with Fisher’s exact test, there was a highly significant difference between treated SRBD patients and all other subgroups (with untreated SRBD P =0.002; with insomnia P =0.002; with RLS/PLMD P =0.008).

Prehistoric fish were always bigger than contemporary Atlantic salmon and brown trout ( figure 1 a ), with highly significant differences for 1-, 2- and 3-year-old fish despite the limited archaeological sample size ( t -tests>3.5, p <0.002 in all cases).

Survival was lower, but not significantly so, in the STn-positive group (P = 0.07), but this effect was highly significant for patients with node-positive disease (P < 0.002), the curves for node-negative disease being coincident (P = 0.31).