We demonstrate a dose-dependent effect on hRECs by increasing exposure to 1, 5, and 10 mM caffeine citrate, resulting on average in highly significant CBF excitation of 14.2% ( n = 7; p = 0.009), 18.6% ( n = 6; p = 0.023), and 28.8%( n = 6; p = 0.014) over CBF b respectively (Fig. 1 d).
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Although this association only achieved borderline significance, there was a highly significant genotype by diabetes interaction (p = 0.009).
However, with just the 75 native Amazonian species (see S1 Table ), the results were striking: the effect of archaeological context was highly significant (p = 0.009) in explaining the variability in floristic compositions ( Fig 2 ).
The last column in Table 3 shows that the effect of the multimodal emulsion on hair count is highly significant compared with that of the minoxidil and placebo formulations ( P = 0.009 and P < 0.001, respectively).
The correlation between the measured and the predicted skeletal muscle mass difference and the measured skeletal muscle mass was highly significant ( r 2 = 0.90, P = 0.009).
Interestingly, 14 C-sucrose at a molecular weight of 300 Da showed highly significant abluminal uptake immediately following KCl (** p = 0.009) and acidified pH treatment (**** p < 0.0001) ( Figure 1 c), which was then abolished back to baseline after 30 min ( Figure 1 d).
A highly significant relationship and a moderate association with anemia (-2.76, CI 95% -9.26 to -0.22; p -value = 0.009) and strong association with very highly significant relationship was noted with COVID-19 (-5.68, CI 95% -6.34 to -0.48; p -value = 0.000) and sun exposure (5.71, CI 95% 0.80 to 0.49; p -value = 0.000).
Italy also showed a highly significant association between these variables (chisq = 11.536; df = 3; p = 0.009); however, longer professional experience (>15 year) corresponded to women (women: 68.9%; men: 54.6%) while 5–10 years of professional experience was more frequent in men (men: 18.1%; women: 9.0%).
45% [95% CI, 34–59] in non‐CR patients, p = .051) and a highly significant improvement of 5‐year OS ( p = .009), but not of lung‐RFS ( p = .3).
Follow up univariate tests revealed that differences between healthy and participants with RLBP were highly significant ( P < 0.009) for all the EMG-frequency slope data (raw MFslopes and normalised MFslopes), when controlling for age, weight and MVIC (Table 6 ).
The type of ARM has a highly significant association with genital anomalies χ 2 (11), N = 156 = 21.95, p = 0 .009.
Notably, GATA3 exhibited a highly significant enrichment of its binding motif ( p ‐value = 0.009) and showed the greatest predicted alteration in binding affinity due to the SNP among all TFs analyzed (FABIAN score = −0.289) ( Figure 2 A ).
This difference was most evident in the earlier stage group (stage 1 to 2) with median overall survival of 30.0 months (95% CI: 26.4 to 35.1 months) in the warfarin group compared to 23.7 months (95% CI: 19.6 to 31.8 months) in the DOAC group, yielding a highly significant HR of 1.24 (95% CI: 1.06 to 1.45, p = 0.009).
Comparison of the entire group (n=8) showed highly significant down-regulation when quantitated by relative densitometry units (p<0.009).
The mean difference in canine relationship correction was highly significant between Carriere Distalizer (3.5 ± 1.7 mm) and Forsus groups (4.5 ± 2.2 mm) ( P = 0.009, Table 4 and Fig. 4 a).
The positive correlation was detectable very early (3 days) and was highly significant 10 days after the first injection (antibody response and IL‐1β on day 10: r = 0.76, P = 0.009; Figure 3B ).
There was no significant variation with the distribution of sex but there was a highly significant variation of the SCC among different age groups (P<0.009) where the highest incidence was reported in patients above 70 years old (12/34 cases, 35.3%) followed by 40-70 years (six cases in the age range of 41-50 years, five cases in the age range of 51-60 years, and six cases in the age range of 61-70 years) (Table 3 ).
A highly significant positive correlation was seen between NLR and RDW ( r = 0.260, p = 0.009).
This correlation is positive ( r = 0.38) although moderate, but highly significant ( p = 0.009) (Fig. 3 A).
Strikingly, E-CAD protein expression was a highly significant prognosticator of OC patients at the advanced-stages (III, IV) ( p < 0.009, log-rank ) ( Figure 3 ).
The association between cause of admission and OD is highly significant ( p -value = 0.009).
This difference was highly significant (log-rank test p =0.009), with postoperative therapy reducing the risk of death by 0.293-fold ( p =0.013); see Kaplan–Meier analysis ( Figure 5 , Table 2 ).
However, in the context of the RNA stem–loop and the extended stem–loop construct, co-transfection of the MS2-SRp55 plasmid led to a highly significant enhancement of splicing ( Figure 5 B and C, compare lanes 3–6; P -value = 0.009 and 0.002).
Resistance was more common among urinary than among fecal strains within each phylogenetic group, the difference being highly significant for groups B2 and D strains ( p = 0.009 and p = 0.003, respectively) and of borderline sig-nificance for groups B1 and A strains ( p = 0.05 for both).
In contrast, highly significant negative correlations were seen between the retromolar space area and whole tongue thickness during both respiratory phases (inspiration r = -0.92, p < 0.009; expiration r = −0.96, p < 0.002, Figure 4 ).