“highly significant”

1a ), supra-threshold amplitudes of wave I of the ABR (in response to 50-μs clicks) remained low and showed significantly shallower growth with sound intensity, compared to pre-exposure values (repeated measures analysis of variance (ANOVA) for pre-exposure and 4-week post-exposure data showed a significant effect of group, p = 0.043, and a highly significant interaction between time of measurement and sound intensity, p = 0.0001; Fig. 1b ).

Similarly, at 25 μg/mL (gluten coated IC50), a highly significant difference (P-value ≤ 0.0001) is noted compared to sericin-coated particles, accompanied by a 40% reduction in cell viability.

The heterogeneity across studies was substantial and highly significant (I2 = 99%, P < 0.0001), indicating that the observed variability was not due to chance alone.

Measurement error The ANOVAs for centroid size and shape both reveal that the “Individual” main effect is highly significant ( P < 0.0001), which means that the variation among flowers greatly exceeds the measurement error due to “Imaging” and “Digitising” ( Table 1 ).

We found a highly significant positive correlation between nuclear ERβ and ovarian cancer marker CEA ( p < 0.0001; 95% confidence interval (CI) 0.1598–0.4465) (Table 4 ).

This was confirmed by the p values of the chi-square for the log-rank test that was not significant for the MAI (p = 0.3042), close to significance for MED (p = 0.0651), and highly significant for FA2 and PC2 (both, p < 0.0001).

We further noted that the expression of ICAM-1 in de-differentiated tumors, defined as those with low PMEL expression (Supplementary Table 5 ), was a highly significant prognostic factor, where low ICAM-1 expression correlated with diminished MSS ( p < 0.0001, HR 25.1, 95% CI 6.0–104.6) with median survival of 8.4 months ( n = 10) for low ICAM-1 expression compared with an estimated 128.4 months ( n = 9) for high ICAM-1 expression (Fig. 5b ).

A repeated measures ANOVA of attractiveness ratings for covered, partially covered, and uncovered displays with a Greenhouse-Geisser correction showed a highly significant main effect, F (1.27, 75.04) = 23.99, p < .0001, η p 2 = .29.

Kruskal-Wallis analysis revealed a highly significant difference among the groups ( P < 0.0001).

The overall distribution of patients in terms of q-PCR and cytogenetics is given in table below ( Table 6 ) along with Pearson correlation ( Table 7 ) showing highly significant correlation between the two ( P <0.0001).

The effect of treatment with fungal extracts, regardless of species, was highly significant compared to caged bees fed only sugar syrup (DWV sugar controls vs. all mycelium treatments: 2-tailed t-test, n = 58; t = 4.33, p = 0.0001, ΔΔCt fold change = 23.0).

“In-within” multiple comparisons determined that this increase in AGO1 during reactivation was highly significant ( p < 0.0001) compared to levels of AGO1 during latency (Fig. 7 a, right).

The mean wheal size of S-DP was significantly higher than C-DP across all dilutions, which was highly significant with P value of <.0001 ( Table 2 , Figure 3 ).

The correlation matrix shows a highly significant relationship ( r = 0.38–0.43, P < 0.0001) between all three scores (Table 4 ) indicating internal validity in scores assigned for each measure.

All 3 tested strips produced highly significant increases (improvements) in both MCA and nasal volume from baseline ( P < .0001 for all 3).

Although the linear effect of saponin concentration was not statistically significant (F = 3.39, p = 0.0814), the quadratic effect was highly significant (F = 117.50, p < 0.0001), confirming the curvature of the response.

But the mean increase was minimal 5.83% in Group D (4 beats, P = 0.0848), when compared with Group E 14% (9.81beats; P = 0.0152) and Group C 30% (24.9 beats; P < 0.0001), which was highly significant ( P < 0.0001).

The effect of the genotype and pairwise-comparisons between the associated genotypic groups were highly significant ( p < 0.0001) (Fig. 4b ; Supplementary Table 4 and Supplementary Data 4 ).

We confirmed a highly significant positive correlation between these two parameters (Spearman's R = 0.74, P < 0.0001; Fig. 5 c).

This difference was highly significant ( p <0.0001).

There is consistently more D1 dimensions in Group II as compared to Group I in each of interdental sites and these differences were found to be statistically significant for PM/CA, CA/LI and LI/CI while the difference was highly significant with CI/CI, CI/LI, LI/CA and CA/PM (p < 0.0001). 5 Discussion In search of definitive guidelines for attaining esthetics in relation to the proportionate existence of white and pink components, several clinical trials have been reported in the literature pertaining to PCA locations ( de Castro et al., 2006 , Sarver, 2004 ).

The effect of transition-based surprise was indeed significant in the new model (F(1, 205)=4.35, p<0.039), but LoT complexity effect remained highly significant (F(1, 205)=106.28, p<0.0001).

Our model results (see Methods for details) show that the differences between chimpanzees from Ngogo and Issa were highly significant in the δ 13 C values ( χ 2 = 61.45, df = 1, p < 0.0001) and the δ 15 N values ( χ 2 = 80.67, df = 1, p < 0.0001), with Issa chimpanzees being less depleted in 13 C, and much lower in 15 N (Fig. 2c , Table 1 ).

Likewise, the difference between the T1/T2 and T3/T4 groups was highly significant (p = 0.0001) ( Figure 3 ).

Table 2 shows that the model is highly significant with a low p -value ( p < 0.0001).