“highly significant”

However, highly significant ( P < 0.0001) effect of both zeitgeber time and zeitgeber time × experimental groups interaction was observed on per gene expression.

30°, the difference is highly significant for Tcn12 (Mann–Whitney U test, P < 0.0001) but not for T1 ( P = 0.32).

Coumarin was the most notable for its highly significant interaction ( P < 0.0001), alongside a significant cultivar main effect ( P = 0.022) and a non-significant altitude main effect ( P = 0.103).

Moreover, the combined treatment promoted a highly significant increase in the expression of proteins involved in mitochondrial biogenesis, such as PGC-1 α (+284.9%, p < 0.0001) and SIRT5 (+39.5%, p = 0.02), compared to sedentary mice ( Figure 7 ).

These differences remained highly significant after controlling for age (ANCOVA p -values <0.0001 to 0.0012).

Statistical analysis for color strength (Two-Way ANOVA with interaction) Statistical analysis provided in the Table 5 confirm that (a) Fabric type has a significant effect on K/S ( p < 0.001), (b) Binder ratio (gelatine: alginate) has a very strong and highly significant effect ( p < 0.0001), (c) Dye concentration significantly affects K/S ( p < 0.0001), and d) There is also a significant interaction between fabric and ratio ( p < 0.001), meaning that the effect of the binder ratio depends on the fabric type.

Meta-analysis resulted in a highly significant ( p < 0.0001) result pointing to a benefit of vitamin C against melasma compared to placebo or no treatment ( Figure 2 ).

In contrast, MWL showed highly significant group differences at all time points (day 7: F (3,65) = 132.66; day 10: F (3,65) = 120.39; day 14: F (3,65) = 109.59; all P < 0.0001; Fig. 3a ).

2 F ), and this overlap is highly significant ( P < 0.0001 by Fisher’s exact test), proving the similarity of CCGs identified in both NAFLD-HCC screens.

Two biological replicates were analyzed for all conditions (i.e., n = 2 per condition), and highly significant ( P < 0.0001) Pearson correlation coefficient values were obtained for each replicate set ( r = 0.9 and 0.855 for p65 ChIP replicates; r = 0.849 and 0.85 for BMAL1 ChIP replicates, and r = 0.890 and 0.888 for CLOCK ChIP replicates in saline and LPS conditions, respectively) ( Supplemental Fig.

Highly significant effects ( p < 0.0001) of Hd1 and Ghd7 on HD were detected in all the three trials ( Table 1 ).

The mean number of blood vessels market with CD105 is higher in tumor mass then at its base, p value of the Student t test being highly significant (p<0.0001).

ty} \oddsidemargin -1.0in \begin{document} \chi_{\left(1 \right)}^2 = \,\,\frac{{{{\left({532\,\, \times \,\,53\,\, - 13\,\, \times \,\,73} \right)}^2}\, \times \,\,671}}{{545\,\, \times \,\,126\,\, \times \,\,605\,\, \times \,\,66}} = 181.7 \end{document} The large chi-squared value evidenced a highly significant association between postoperative nausea and vomiting in surgical patients ( p < 0.0001), and the hypothesis of independence between the two symptoms was rejected.

As expected, there were highly significant differences among the three regional comparisons (Friedman ANOVA: χ 2 2df = 77.82; p <0.0001).

The trophozoites treated with nitroxoline showed a highly significant decrease in ATP levels compared to the negative control, p < 0.0001 (****) ( Figure 7 ).

A two-way ANOVA analysis using Prism 6 software (GraphPad) identified a highly significant difference in the G and U content between peaks and non-peaks ( p -value < 0.0001).

The model for CCI was highly significant (F 3,157 = 42.837, p < 0.0001) and explained 45.5% of the variance ( R 2 = 0.455; R 2 adj = 0.444).

The difference was highly significant (p < 0.0001) implying that serum zinc levels of the cases were significantly lower than that of controls.

A highly significant association also existed between the number of circulating aPMPs and CDAI ( p < 0.0001) ( Figure 2 g).

This posed a highly significant difference between the two B12 forms ( p < 0.0001).

The difference between the two groups was highly significant with regard to PD and CAL ( P =0.0001 and P =0.001, respectively; Table 2 ).

The CLEC treatment provided an accelerated wound closure that was highly significant ( p < 0.0001) over time compared to the other two treatment arms.

Quantitation of total tube length showed a highly significant and robust increase above that of controls going from 1.46 ± 0.5 mm in untreated cells to 5.46 ± 1.4 mm in Dsi2‐treated cells ( P < 0.0001; Figure 3 A), representing nearly a three fold increase.

CD8 and Foxp3 expression also demonstrated a highly significant positive correlation (R 2 =0.27; P<0.0001).

By contrast, in 0.3 pmol MO zatxn7 SPL morphants, we observed a highly significant decrease in the number of Purkinje cells at 5 (90+/−18, n = 5, p <0.0001), 6 (104+/−25, n = 6, p <0.0001), and 7 dpf (143+/−23, n = 6, p <0.0001) ( Figure 6D–6F ), strongly suggesting that partial zebrafish atxn7 depletion partly compromised, but did not slow down Purkinje cell differentiation.