“highly significant”

Highly significant correlations ( P < 0.0001) were observed between all the four neutralization assays employed in this study ( Fig. 4E–J ).

This result demonstrates that there is highly significant, tight genetic linkage between the 3-aa deletion mutation and spinosad resistance in the SZ-SpinR strain (P < 0.0001, Fisher's exact test), and confirms that the 3-aa deletion mutation is recessive. 3.4.

Satisfaction and Perceptions of Quality and Patient Safety Course and Implemented Activities A pre–post analysis of 51 students’ responses using the McNemar test revealed a highly significant positive change in their perceptions towards the quality and patient safety course ( p < 0.0001).

All intergroup differences were highly significant ( P = 0.0001; pairwise comparisons P < 0.001).

The pooled analysis demonstrated a profound and highly significant reduction in the incidence of IANI when coronectomy was performed compared to total extraction (Peto OR = 0.23; 95% CI (0.13, 0.39); p < 0.0001) (Figure 6 ).

This improvement was highly significant ( p < 0.0001) in terms of the paired comparison of AUC between the two versions of the tool.

As expected, the main effect of Load was highly significant, reflecting progressive APS decreases with increasing loads ( F (2,76) = 21.46, P = 0.0001).

brachypus at 2 g/kg in feed or 2 g/L in water led to a highly significant reduction in total cholesterol (by up to 65.9 ± 1.72 mg/dL, p < 0.0001) and a significant elevation in HDL cholesterol (by up to 25.9 ± 1.72 mg/dL, p < 0.0001) in broiler chickens.

Similarly, GC2 cells exhibited a significant and dose-dependent reduction in sphere formation following treatment with pemigatinib, with both concentrations showing highly significant effects (**** p < 0.0001).

The model was found to be highly significant ( p -value < 0.0001).

The differences between knockdown and mortality of the two washing techniques at washes 15–30 were highly significant at all wash points (p<0.0001). 90% knockdown was maintained up until the 10 th wash for the machine washed clothing, KDW 90 10.0 (95% CI 6.1–13.4) and up until the 6 th wash for the WHO method washed clothing (KDW 90 6.4; 95% CI 5.0–7.7) ( Fig 3 ). 90% mortality was not achieved for any of the treatments and therefore the LW 90 was not calculated.

Kras Low mice exhibited ∼26% recombination, Kras Mod mice ∼46%, and Kras High mice nearly complete recombination (∼98%) with all comparisons highly significant ( P < 0.0001).

5d ) were highly predictive of dhurrin concentration owing to a marginally significant additive (linear model coefficient estimate t = –2.18, P = 0.03) and highly significant quadratic ( t = 4.97, P < 0.0001) effect on untransformed dhurrin levels.

However, both Simpson and Shannon indices showed highly significant difference in microbiota diversity ( p < 0.0001) with increased diversity at 7 DPI compared to 2 DPI (Figures 4 B,C).

Bold values indicate highly significant main effect of infection (p < 0.0001), asterisks indicate significant time by infection interaction, and italics indicates no significant main effect (significant interaction only).

Analyses by finer time periods suggested a constant decline in HBsAg seroprevalence nationwide between 1973–1984 and 2019–2021 ( figure 2A ), which was highly significant in a linear regression model (−0.20% per year, p<0.0001; APC=−3.77, 95% CI −4.15 to –3.38) ( figure 2B ).

Patients with ER-negative status (EFS: P = 0.043) had poorer outcomes and RT was associated with highly significant increase in LRRFS, EFS and OS (P < 0.0001, P < 0.001 and P = 0.017). status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Received 2013 Dec 4; Accepted 2013 Dec 31; Collection date 2014.

Repeated measures ANOVA showed highly significant effects of age (p<0.0001), the interaction of age with Lepr genotype (p<0.0001), the interaction of age with BN congenic genotype (p = 0.0055), and lesser significance for Lepr genotype and BN congenic genotype interaction (p = 0.0330).

Consistent with previous findings reporting limited dosage compensation in the homogametic avian male, the total proportion of genes on the Z-chromosome that showed lower expression in females was highly significant in both RJF ( Figure 1 ; 87% was lower in females, χ 2 = 275.8, p<0.0001) and WL (90% was lower in females, χ 2 = 312.2 p<0.0001) compared to a 50/50 distribution.

Also highly significant elevation ( p < 0.0001) of Cu levels in the lungs was found in non-pregnant exposed (54.4 ± 2.8 μg/L) mice compared to non-pregnant shams (13.0 ± 1.2 μg/L).

The reduction in EASI scores was statistically significant as early as week 2 ( P = 0.0003), with a highly significant improvement noted by week 12 ( P < 0.0001) [ Figure 1a ].

This separation is highly significant ( p < 10 −4 , permutation test, see Materials and Methods).

In all areas that were analyzed (CA1, CA3, hilus, and dentate gyrus), there was a highly significant main effect for group ( p < 0.0001 for all areas) but not for treatment (CA3: p = 0.2708; CA1: p = 0.6038; dentate gyrus: p = 0.6610; hilus: p = 0.8269).

The analysis of variance for stem rust reaction showed highly significant differences ( P < 0.0001) among accessions included in the whole collection, the durum sub-sample and Q2 group.

A statistical comparison of astigmatism values between the groups showed a highly significant difference ( p < 0.0001) ( Table 1 ). 3.8.