“highly significant”

Pairwise comparisons showed a highly significant increase in similarity in PK pairs (PK: paired: M = 0.03, SD = 0.04; shuffled: M = −0.01, SD = 0.02; t (18) = 4.1, P = 0.0007, CI: [0.018–0.058], Cohen’s d = 0.94).

Quantitative analyses confirmed that the Mrp2 immunogold labelling density in Wortmannin-inhibited samples remained as high as in controls despite insulin stimulation, while insulin also in the new media conditions with DMSO still led to a highly significant ( P = 0.0007 vs. control and P < 0.0001 vs. insulin + Wortmannin-treated cells) decline of Mrp2 levels at the plasma membrane (Fig. 5 h).

The interaction of clade × latitude was also highly significant ( p = 0.0007), indicating that the two evolutionary lineages respond differently in their timing of adult activity at different latitudes.

A highly significant association between allele imbalance on 17p and 17q in this material has been observed previously (Fisher's exact test, P = 0.0007; data not presented).

the everyday foot score was highly significant ( P = 0.0007).

The poor responder group also had increasing IL-8 between BL and W12 ( p = 0.041) with a highly significant increase observed between W6 and W12 ( p = 0.0007), not seen in those who had a reduction in CST.

Pixel-level quantification of GFP fluorescence demonstrated that the IL-13-induced inhibition of S protein-mediated viral transduction efficiency was highly significant ( P = 0.0007, Fig. 5C ).

Results There was a highly significant positive correlation between the two sets of antibodies ( r s = 0.621; P = 0.0007).

In contrast, En1-Cre; Srd5a3 fl/- mice showed a severe and highly significant (p=0.0007) motor coordination defect assessed with the rotarod test ( Figure 1G ).

When applying the CV mortality results in univariate Cox regressions, we observed a highly significant risk reduction resulting from supplementing the participants with selenium and coenzyme Q10 for four years, also after 12 years (HR:0.58; 95%CI: 0.42–0.79; P<0.0007).

From BSL to WK16, differences in changes were highly significant between Gr.Suppl.5 and Gr.Suppl.0 (18.3 vs 7.7 nmol/L, t test: p = 0.0007) and between Gr.Suppl.10 and Gr.Suppl.0 (23.5 vs 7.7 nmol/L, t test: p = 0.000001).

Postoperative visual analog scale score was 4.8 ± 1.12 in Group BN, and in Group BF, it was 3.86 ± 1.04 which was statistically highly significant ( P = 0.0007).

However, concurrent manifestation of all three classic signs of loiasis pruritus, Calabar swelling, and eyeworm, was a highly significant predictor of infection ( p = 0.0007).

This increase in seropositivity with age was highly significant (logistic regression p = 0.0007).

The difference between AUC 5–55 of the two probes was statistically highly significant ( p = 0.0007).

The FAS test for letter fluency was most highly significant with a p < 0.0007.

One-way ANOVA showed a highly significant difference in the anxiety score based on respondent's monthly income ( P = 0.0007).

At 10 ng/ml FGF8, the difference in proliferation between both cell lines was highly significant (P = .0007).

The difference in treatment efficacy between Etomoxir and vehicle treatment was statistically highly significant (p = 0.0007).

This difference was highly significant ( P = 0.0007).

A highly significant excess ( p = 0.0007) of DM1 patients presented with cTnI levels greater than the 99 th centile of the range usually observed in the general population (9 patients; 7.6%).

In edible plants, the regression analysis indicates that there is a highly significant relation among management intensity and risk indexes ( R 2 = 0.48, p = 0.0007) (Fig. 4 , Table 8 ).

For 85 ccRCC patients treated with Sunitinib in the IMmotion 150 cohort, the DKC1-high group exhibited significantly increased TERC expression (high vs low, P = 0.014); however, a highly significant increase was seen in female ( P = 0.0007) but not male ( P = 0.18) patients (Fig. 5 B).

This distribution resulted in a highly significant difference (Fisher’s exact test, p = 0.0007) ( Table 3 ).

There was a highly significant correlation between HPyV6 DNA PCR and HPyV6 FISH results ( p = 0.0007; Fisher’s exact test).