“highly significant”

We identified three highly significant module-trait correlations (|AverageCorr | > 0.5, p -value < 8e-4), with each linked to DLB and Control, and composed of CpGs ranging from 39 to 157 (Supplementary Data 2 ).

2A to D ), and the highly significant ( P = 0.0008) reduction in bacterial resistance to some antibiotics from IIS to WWE ( Fig. 2B ), reinforces the need for adequate water treatment for all and preventing natural environmental surface waters having similar community profiles to untreated wastewater.

Concurrently, a highly significant inverse correlation was observed between ROM and degeneration severity (W = 34.22, p = 0.0008).

This overlap is highly significant (OR = 2.0, p = 0.0008, Fisher’s exact test).

5A ), the difference between the HC and PC groups remains highly significant ( p = 0.0008), and the p value for the difference between the PC and mild AD groups decreases ( p = 0.0218 versus 0.0963 in Fig. 5A ).

There was an increase in expansions over the No RFB level for the Weak RFB condition that was highly significant at the 6.7 kb location (p = 0.0008; Fig 1C ).

When categorising based on both signatures, there was a highly significant association with CA9 ( p = 0.0008) and HIF-1α ( p = 0.007) protein expression.

The protection was highly significant, with p = 0.0008 for both treatment groups compared with the controls.

Remarkably, this revealed that, despite the relatively low r 2 for each individual chemokine, a highly significant ( p = 0.0008), four-chemokine model including CCL17 (TARC), CCL11 (Eotaxin), CCL2 (MCP-1), and PDGF-BB could explain about 80% of the variation in the proportion of HMC/CD34 in our cohort of SCD and healthy individuals ( Figure 4 B).

We chose asthma nonetheless for its status as the most prevalent atopy in SIgAD patients (19.1%) [ 18 ], its highly significant GPS test statistic (p = 0.0008), and our access to a highly-powered asthma GWAS for use as an auxiliary data set ( Supplementary Table 1 ).

For CS, breed differences were highly significant ( F = 6.13, p = 0.0008), suggesting breed‐specific size variation.

The NaOCl solution caused a highly significant reduction in post-operative discomfort ( p = 0.0010 day 3; p = 0.0007 day 7) and early painful failures ( p = 0.0008) compared with the control.

These proportions were highly significant by nonparametric test of trend (p=0.0008), but only the severe COVID-19 group reached statistical significance vs.

Mahalanobis distances between groups were highly significant (Mahalanobis distance: 1.953, P = 0.0008).

However, gamma coherence showed highly significant increases during choice compared to must-touch between mPFC and vCA1 ( Figures 1 G and S3 B; mPFC-vCA1 t(3) = 13.760, p = 0.0008), similar to changes reported from T-maze DNMTS tasks. 18 , 19 In addition we found marginal increases in gamma coherence between nRE and vCA1 ( Figure 1 G; nRE-vCA1 t(2) = 3.272, p = 0.082).

A highly significant difference was observed between the maximum stress value for the RC scaffolds versus XYP scaffolds when the deposition time was 45 min ( p = 0.0008, F = 81.55, and critical F = 7.71); however, no significant difference was observed for the elongation at break ( p = 0.24, F = 1.89, and critical F = 7.71).

Wilcoxon rank sum test revealed a highly significant shift towards trajectory-reliance from session 1 (median = 0.0076) to session 2 (median = 0.1973; w = 116, p -value = 0.0008, r = 0.5128), from session 1 (median = 0.0076) to session 3 (median = 0.2757; w = 46, p -value < 10 −5 , r = 0.6781), from session 1 (median = 0.0076) to session 6 (median = 1.0241; w = 2, p -value < 10 −8 , r = 0.7385), from session 2 (median = 0.1973) to session 6 (median = 1.0241; w = 16, p -value = 0.0001, r = 0.6953) and from session 3 (median = 0.2757) to session 6 (median = 1.0241; w = 20, p -value = 0.0014, r = 0.6534).

The increased association of the Firre locus with the nucleolus surface in female versus male cells was highly significant ( P = 0.0008 by one-sample t-test).

Under herbivore-exclusion conditions, at the Joquicingo experimental site, plants originating from Santo Domingo showed a highly significant negative correlation ( r = − 0.61, p = 0.0008), whereas plants originating from Teotihuacán exhibited a significant positive correlation ( r = 0.49, p = 0.0082).

The distribution of hypermethylation and hypomethylation loci among comparison pairs was highly significant (χ 2 (2-df) = 14.17, P = 0.0008).

A highly significant positive correlation between maintaining attention and motivation was found (Spearman correlation, R = 0.53, p = 0.0008).

Weaker correlations, but highly significant, were found between vertical jumps in adulthood and gross motor skills in childhood ( ρ ( n =168) = 0.26, p = 0.0008), body perception ( ρ ( n =166) = 0.29, p = 0.0002), and social skills in childhood ( ρ ( n =168) = 0.25, p = 0.0009).

The 6 months results of HRQoL, sleepiness, depression, cognition, disability and walking speed were all highly significant (p<0.0008–0.0001) and consistent with the results at 12 months (data not shown).

In contrast to the analysis of the first event in the extended follow-up, the number of previous self-harm episodes was highly significant with an increased rate of recurrent self-harm in those with three or more self-harm episodes at baseline (HR 2·05, 95% CI: 1·35, 3·12, p-value=0·0008) and there was a higher rate of self-harm in those referred via hospital (HR 1·64, 95% CI 1·04, 2·61, p -value=0·0348). 3.6.

While rs2555639 was the only SNP that was significantly associated with risk of colon cancer in each of the discovery and validation sets independently, several additional SNPs had highly significant association with risk when combining data from the discovery and validation samples ( Table 5 ), including rs1365611 (OR = 1.73, 95%CI:1.26–2.37, p = 0.0008), rs6844282 (OR = 1.42, 95%CI:1.10–1.83, p = 0.0078), and rs2332897 (OR = 1.74, 95%CI:1.27–2.38, p = 0.0006).