Marginal significance was observed at 19q13.11 (index by rs1345417: p = 1.42 × 10 − 7 ) and 20q12.1 (index by rs12651896: p = 1.81 × 10 − 7 , Figure S1D−F ).
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Correlation of CDX2 with clinicopathological parameters CDX2 expression was inversely associated with lymph node metastasis (high CDX2 expression was associated with decreased lymph node metastasis (RR=1.52, 95% CI: 1.29-1.79, P<0.00001) ( Figure 5 ) however, CDX2 expression was significantly higher in poorly differentiated gastric cancers (RR=1.52, 1.52; and significantly higher in well-differentiated and latent gastric cancers marginal significance compared with 95% CI: 1.22-1.87, P<0.00001) ( Figure 6 ) was observed (RR =0.82, 95%).CI =0.67-1.01, P=0.07) ( Figure 8 ).
Furthermore, a similar association pattern was observed in SNPs near the MIR4458HG gene (distance ~33 kb) in chromosome 5 with marginal significance ( P -value < 1.0E−05) in all models (Table 2 , Additional File 1 : Table S1).
Scadding stage typically remained significant in full models of architectural distortion, fibrotic abnormality, hilar and mediastinal lymphadenopathy, micronodules, reticular abnormality, and traction bronchiectasis, while dropping to marginal significance ( p ≈ 0.001) in full models of conglomerate mass and ground-glass and losing significance ( p > 0.001) in full models of mosaic attenuation. 4.
We then took module scores with marginal significance (i.e., with unadjusted p- values < 0.01) as predictors to construct models, and repeated our main analysis.
Differences were considered significant at p < 0.05, with marginal significance set at p < 0.01.
Conversely, pSD was more frequent in the > 60 years group, with this difference reaching statistical significance in males and a marginal significance in females ( P = 0.0138 and P = 0.053) (Table 4 ).
Lower tNAA concentrations were associated with greater mood/cognition symptom improvement at marginal significance ( B = −0.62, SE = 0.25, X 2 = 5.89, p = 0.015).
We also observed a marginal significance, still in favor of AROS, in the frequency of strongly agree evaluations ( z = −2.3, p = 0.015).
A lack of an association between each SNP and MIH was found in analyses performed for frequency distributions of major homozygotes, heterozygotes, and minor homozygotes (except for the rs4811117 polymorphism, for which the p -value reached marginal significance at p = 0.017, which is on the borderline if the Bonferroni-corrected significance level of p = 0.05/3 = 0.017 is used for the global chi-squared test with the further tests treated as post-hoc tests).
At R2, we found an interaction effect between Condition and Flanker , and post-hoc analyses (α = 0.0125) uncovered marginal significance in the verb-final condition (β = –0.012, SE = 0.005, t = –2.455, p = 0.018) and insignificance in the verb-initial condition.
For the animal stimuli type, there was significantly higher brain activation in the congruent condition in the vlPFC, t (21) = 2.295, p = 0.032 (marginal significance after FDR corrected), the SupraMarginal gyrus (SMG), t (21) = 2.529, p = 0.019 (FDR corrected), and the angular gyrus, t (21) = 2.829, p = 0.010 (FDR corrected) compared with the baseline.
crop height, number of tillers and root length, produced a marginal significance between soil textures ( P =0.02, df: 3, 212, F value: 4.96, F critical: 2.64, single factor ANOVA), with clay loam soils having the greatest reduction to crop biomass ( P =0.02, df: 69, t.stat: 2.14, paired unequal variance post hoc T test).
ACTR3_SEPEP.1_C4 was associated with the shared peptides, and it was lower in tumors compared with NATs with a marginal significance ( P = 0.02).
Regarding overall sleep quality, sleep deprivation symptoms were more prevalent during the first week of the academic year (n=28; 7.3%) compared to summer vacation (n=27; 7.0%), but with marginal significance ( p =0.023).
Attitudes towards violence In the waitlist orphanages (b 1 ), the difference between first and second follow-up reached marginal significance, ψ ^ = −0.76 (−1.52, 0.01), p < .025.
Pairwise comparisons of treatment conditions via one-way ANOVA and Dunett posthoc test reached only for the parameters protein amount per EV and number of EV per μg protein marginal significance for EVs derived from CPRP-treated 3D cultures ( p = 0.0278 and p = 0.0461, respectively).
The difference in Diff-BP showed marginal significance for SBP ( P = 0.029) and MBP ( P = 0.042).
Metabolites from amino acid metabolism We observed reduced circulating levels of 15 out of 19 commonly detected amino acids (missing for cysteine), including three branched‐chain amino acids (BCAAs), and a marginal significance for phenylalanine (raw P = 0.03; adjusted P = 0.14), in different disease groups compared with NGT controls.
Luminal A-like subtype, characterized by high-expression levels of estrogen and progesterone receptors (ER and PgR, respectively) and low ki67, showed marginal significance at the univariate logistic regression ( P = .038).
There was a greater reduction regarding these parameters in the intervention group between which body fat mass reached statistical significance and weight loss presented marginal significance ( p = 0.038 and p = 0.058, respectively).
However, there was a slight increase in the left condyle’s angulation within the lag screw group, showing marginal significance (preoperative measure: 24.83 ± 6.37 vs. postoperative measure: 32.5 ± 4.93; P = 0.04).
Accordingly, of the two non-significant studies in our sample, one of them–the ACCORD trial [ 60 ]–had a replication with a significant result–in this case, a large meta-analysis that reached marginal significance (p = 0.04).
Marginal significance (i.e., without Bonferroni correction) was observed for the comparison of water to citrus in subject V1XS8 ( p = 0.04) and to coffee in subject O9ZEA ( p = 0.04).
The risk of composite outcome was lower in users than in non-users with marginal significance (adjusted HR 0.85, 95% CI 0.72 to 0.99; p=0.040).