The abnormal MRI group also had lower peak GH levels than the normal MRI group with marginal significance (0.6 ng/mL vs 4.3 ng/mL, P =0.059).
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Longitudinal analyses with adjustments for age and gender showed that low ASM with limited mobility was associated with increased mortality ( p = 0.003), the presence of one or more ADL disabilities ( p = 0.059; marginal significance), the presence of one or more IADL disabilities ( p = 0.030), and with frailty ( p = 0.037) but not with injurious falls ( p = 0.235).
For positive symptoms, GLM only showed a marginal significance for deictic in SO ( z = −1.884, p = 0.059).
Omitting the time between tests factor resulted in marginal significance of mutual mutations status (HR=1.43, P =0.059).
Sensitivity analyses excluding the identified outliers ( Supplementary Table 4 ) showed results consistent with the primary analysis ( Supplementary Table 5 ), except that the main Group effect on LDL-c shifted from marginal significance ( p = 0.059) to statistical significance ( p = 0.047), confirming the robustness of the clinical findings. 3.1.2 Animal study 3.1.2.1 Lipid metabolism For TC levels, LMM analysis identified significant main effects of both prenatal Poly I:C exposure [ F (1, 14.1) = 15.410, p = 0.002] and sex [ F (1, 53.5) = 5.730, p = 0.020].
Additionally, a marginal significance was found between the PSQ of #L1 and #L3 at D10 (the mean PSQ difference of #L1 minus #L3 was 0.67, p = 0.059).
Marginal significance was found for the correlation between the change scores of the picture-updating task and the changed RP amplitude of stimulus-based action ( rs = 0.482, p = 0.059), showing that improved performance of executive function after training was positively related with the increased RP amplitude in stimulus-based action.
After adjusting for BMI, patients with endometriosis showed marginal significance in obstetrical complications, including SGA (adjusted OR, 1.568; 95% CI, 0.984–2.499; p =0.059) and postpartum hemorrhage (adjusted OR, 1.632; 95% CI, 0.972–2.737 ; p =0.064).
MDS-UPDRS motor scores exhibited marginal significance in the right striatum (β = −0.009, p = 0.059).
In the subgroup treated with AC regimen, grades of ALDH1+ tumour cells increased after PST with a marginal significance ( P =0.059) ( Figures 2C–F ).
We found a bimodal distribution with marginal significance (Hartigan’s dip test: P = 0.059, SI Appendix , Fig.
This association was markedly stronger in the elevated BP group: the risk for Q4 participants increased threefold (OR = 3.21, 95% CI: 2.26–4.61, P < 0.001), and Q3 showed substantial risk (OR = 2.43), while Q2 showed marginal significance ( P = 0.059).
Besides, the mesangial proliferation score significantly decreased in LP-treated group but decreased in Akk-treated group with a marginal significance ( P = 0.059) ( Fig. 2J ).
In contrast, Influenza A was strongly associated with headache (OR = 3.59, 95% CI: 1.44–10.24, p = 0.009), anorexia (OR = 4.76, 95% CI: 2.03–11.09, p < 0.001), and showed a marginal significance (OR = 1.57, CI: 0.98–2.50, p = 0.059) with fever, whereas cough showed a negative association (OR = 0.29, 95% CI: 0.11–0.77, p = 0.010).
CKD reached marginal significance (aHR 2.15, 95% CI 0.97–4.76; p = 0.059).
Kaplan–Meier estimates of the cumulative PFS for patients with methylated and non-methylated BRMS1 promoter had marginal significance ( P =0.059, log-rank test) whereas that of the cumulative OS was significantly different among the two groups ( P =0.003, log-rank test) ( Figure 2C ).
Interestingly, positive axilla on MRI showed marginal significance for predicting HNB (adjusted OR, 2.7; P = 0.059), following after lymphovascular invasion (adjusted OR 3.4; P = 0.023).
While α-tocopherol intake showed no significant difference ( p = 0.484), β-carotene approached marginal significance ( p = 0.059).
A high score in the fast food pattern was positively associated with risk of anemia in children entering puberty (PR = 1.767, 95% CI: 1.026~3.043, p = 0.039), especially in girls after menarche, with marginal significance (PR = 1.740, 95% CI: 0.977~3.097, p = 0.059).
As compared with HER2 wild-type tumors, HER2 mut showed similar ORR (63% v 72%, OR, 0.67 [95% CI, 0.31 to 1.55]; P = .33), numerically shorter PFS (median: 9.4 v 12.1 months, HR, 1.36 [95% CI, 0.90 to 2.06]; P = .14), and significantly shorter OS (median: 23.7 v 34.4 months, HR, 1.56 [95% CI, 1.02 to 2.38]; P = .04; Figs 4 A- 4 C), reaching marginal significance in multivariate analysis after adjustment for covariates (HR, 1.53 [95% CI, 0.98 to 2.38]; P = .059).
Healthy and CD children differed at the level of KEGG modules, with marginal significance explaining 9.4% of the variation ( P =0.059; Supplementary Figure S3 ).
HIV-1 gag sliding window analysis and amino acid diversity Sliding window analysis showed that one window (201—300) had a significantly higher median entropy score in chronic HIV-1 infection stage compared to recent HIV-1 infection stage, ( p = 0.017) and another window (401 – 500) showed a similar trend but had marginal significance, p = 0.059 (Fig. 2 ).
Controlling modifying parameters, using antihypertensive medication yielded lower EIF with marginal significance ( P = .059) and OR = 0.618.
However, when including only the 70 Hz and sham groups, the ANOVA showed a marginal significance for the interaction effect of the group and the time [ F (1, 55) = 3.729, p = 0.059, η 2 = 0.063].
The ARB/AML combination exhibited a negative (infra-additive) interaction with a marginal significance ( p = 0.0593) in present study.