“marginally significant”

We detected a significant excess of variants in two of the pathways in CVID patients when compared to controls: Fc epsilon RI signaling and cytokine–cytokine receptor interaction pathways ( P < 0.001 and 0.002, respectively), plus two other marginally significant pathways after applying multiple test correction: cytosolic-DNA sensing, and NFKB signaling ( P = 0.002 and 0.001, respectively).

In the EUR GWAS for Aβ, we found that rs76490923 had a marginally significant association (beta = −0.1240, SE = 0.0404, p = 2.20 × 10 −3 ) with Aβ in EUR population. rs76490923 was associated with decreased Aβ levels and exhibited the same effect directionality (beta coefficient, −0.1240 [EUR] vs. −0.1661 [EAS]) as in our EAS GWAS results (Fig. 2 ).

Significant negative concordance was also identified between the social disinhibition behaviour symptom cluster and the thalamus (Table 2 , p = 1 × 10 −3 ) as well as marginally significant negative concordance with the accumbens ( p = 2.3 × 10 −3 ) and positive concordance with the pallidum ( p = 0.47 × 10 −2 ).

The results demonstrated that MX2 displayed the most significant eQTL with rs398206 ( P = 6.6e−15; linear regression), while none of the other genes in the TAD displayed even a marginally significant eQTL after adjusting for multiple testing (Bonferroni-corrected cutoff at P < 0.0024 for 21 genes; Supplementary Table 9 ).

A smaller cluster in the symmetric region was marginally significant (Table 2 ). 3.4 Correlation analysis Significance for correlation analysis was determined as p < .0025 (0.05/20 for Bonferroni correction considering five clinical parameters and four stages) for each cluster.

The model indicated a significant increase in mutation frequency with age in blood, a marginally significant increase in saliva, and no difference in oocytes ( Z test P = 2.7 × 10 −3 , P = 5.7 × 10 −2 , and P = 0.688 for blood, saliva, and oocytes, respectively; Fig. 1B and table S4).

We found a significant difference only for the physical training group and a marginally significant difference between pre- and post-training correlation values for the audiovisual experience group (physical training group: z = 2.96; p = 0.003; audiovisual experience group: z = 1.98; p = 0.048; auditory experience group: z = 0.97; p = 0.3297).

Straylight did not correlate significantly with BSCVA at baseline ( r = 0.06, p = 0.7), but correlated significantly at three and 6 months and was marginally significant at 12 months ( r = 0.47, p = 0.003; and r = 0.50, p = 0.003; and r = 0.3, p = 0.09; respectively).

On days when participants felt lonelier than usual, they were more likely to forget meetings (OR = 1.07, p=.052), although this effect was marginally significant; moreover, forgetting meetings predicted higher loneliness the next day (b = 4.2, p=.003).

The same pattern was shown about the estimate of avoidance, with a marginally significant difference between clinician-assisted and waitlist groups in avoidance ( p < 0.003), but not between clinician-assisted and self-guided, or self-guided and waitlist conditions ( p > 0.05).

We found a significant indirect effect of the trust in the government on attitudes toward vaccines (TTG → PSS → vaccine attitudes), b = −0.05, z = −2.44, p = 0.01, a significant “a” component (TTG → PSS), b = −0.26, z = −4.35, p < 0.001, and a marginally significant “b” component (PSS → vaccine attitudes), b = 0.22, z = 2.94, p = 0.003.

We also found significant and marginally significant correlations between ERCC1 and ACTL6A expressions after 50% ( p = 0.003) and 100% ( p = 0.06) CCRT, respectively, among the HNC patients, which supports the hypothesis of ACTL6A-mediated NER activation.

In addition, there was a significant interaction between Duration and Intensity, F (1, 42) = 8.7, p = .005, ηp2 = .17, due to a significant difference between the high and low magnitudes in the high intensity light bulb conditions in comparison to a marginally significant difference in the low intensity light bulb conditions (10.8, p = 0.003, vs. 8.9 seconds, p = 0.06, respectively).

The interaction between Emotion and Question was marginally significant [ F 1 (2,118) = 6.41, p < 0.003, η 2 = 0.01; F 2 (2,36) = 1.82, p < 0.18, η 2 = 0.01], as the effect of Emotion type was largest for the innateness question Δ = 1.37 (for the face and body questions, Δ = 1.08 and Δ = 0.89, respectively).

The 12- and 14-repeat alleles exhibited significant associations with p values of 5.66 × 10 −5 and 3.40 × 10 −5 , respectively, while the 15-repeat allele was marginally significant ( p = 0.003) (Table 1 ).

Out of all the service member characteristics used to predict Family Study survey response, only the interaction term for children and recruitment group was marginally significant after Bonferroni alpha adjustment ( p < .003; .05/15).

Marginally significant associations were found with FEV 1 and FVC (p = 0.003 and p = 0.008, respectively) in one of the family-based cohorts, but these associations were not significant after correcting for multiple comparisons.

An exploratory analysis indicated a marginally significant inverse association between achieved 25(OH)D levels and 24-h SBP ( p = 0.003), but this finding should be interpreted cautiously due to small subgroup sizes and post hoc design [ 120 ].

Repeated-measures ANOVA of 3 (social priming group: others inclusion, friend exclusion, stranger exclusion) × 2 (stimulus type: Go, Nogo) on the amplitudes of the N270 components in the frontal region evoked by the Go/Nogo task found that: The main effect of social priming group was marginally significant F (2, 85) = 6.06, p = 0.003, η p 2 = 0.125, the main effect of stimulus type was not significant F (1, 85) = 1.39, p = 0.242, and the interaction between them was not significant F (2, 85) = 1.21, p = 0.304.

One-way ANOVA results exhibited a marginally significant interaction between experimental diets in terms of essential amino acids (F (3,8) = 11.371, P = 0.003), nonessential amino acids (F (3,8) = 0.407, P = 0.752), and overall amino acid pools (essential plus nonessential) (F (3,8) = 7.355, P = 0.011).

However, there was a marginally significant trend towards an inverse association between the achieved 25(OH)D level with 24-hour systolic BP (−0.196 per ng/mL 25(OH)D, 95% CI (−0.325 to −0.067); p = 0.003).

There was no significant difference between F IS and F e in short-lived species (16 cases with F IS < F e , compared to 10 with F IS > F e , P = 0.33), in contrast to herbaceous perennial species that present a marginally significant trend (23 cases with F IS < F e , compared to 11 with F IS > F e , P = 0.057) and woody species that present a significant trend (55 cases with F IS < F e , compared to 27 with F IS > F e , P = 0.003).

37 The burden of de novo missense variants is also higher in constrained genes compared to non-constrained genes (fold = 1.57 versus 1.22), although it is marginally significant in both constrained and non-constrained gene sets (p = 3.3 × 10 −3 and 0.045, respectively).

There was a highly significant interaction between the effects of seizure and cortex for occurrence [ F (1,42) = 9.071, p = 0.004] and Up states index of spontaneous activity [ F (1,42) = 12.7, p = 0.001]; and a marginally significant effect of the two on Up state amplitude [ F (1,42) = 4.172, p = 0.047] and rectified area [ F (1,42) = 4.151, p = 0.048] ( Supplementary Text , Section 2.1.2 , Table 9 ).

In this Cox model, age, pathological TNM classification, and TP53 mutation were also significant or marginally significant factors for overall survival ( p = .004, .073, and .051, respectively).