“may be significant”

Never- theless, Nettleship and Henshaw remark that the negative correlation between pneumonia and adenomata may be significant.

Compared with blunt liver trauma in adults, there may be significant differences in the size, shape, and CT attenuation value of the trauma regions in children with blunt liver trauma [ 30 ].

While there may be significant synergies in effectively leveraging open research, there is no denying a potential clash between the often high-minded goals of open science and the highly-competitive culture of drug development.

Accordingly, the coinciding increase of CD73 in PDAC cells may be significant in promoting extracellular adenosine-mediated immunosuppression.

Nevertheless, this volume–outcome association may be significant in terms of the high-risk and low-volume of esophagectomy procedures for cancer.

Sequence repositories, databases and tools for sequence analysis should regularly review the evidence for TDF RAMs in order to highlight all sites that may be significant in mediating resistance. ii In the context of failure of viraemic suppression in a patient prescribed therapy, assessing and supporting drug compliance is crucial, ideally together with viral sequencing. iii Therapeutic failure of TFV – whether in the presence or absence of known RAMs – should lead to an expert clinical decision about switching therapy or combining agents, as long as adherence has been optimised and supported.

As a result, there are significant parallels we can derive from strategies used in brain pathology, with the caveat that there may be significant and unappreciated differences between brain and spine.

It is likely that marriage benefits older men and women via different pathways, although the distress from losing a spouse and the loss of emotional support may be significant for both.

In particular, administrative and research benefits may be significant.

Similarly, Arthrobacter , suggested to be closely associated with the causative agent of chalky disease, and Corynebacterium anaganae , causative agent of a bacterial septicemia of cicadas 47 , were detected and may be significant with respect to overall health of cicadas in MD.

This shift in sediment type and mineralogy may be significant when considering the sediment inventory of organic carbon.

As a result, if small town is impacted by a coastal hazard there may be significant short- and long-term impacts on the town.

A long-term RCT between these two may be significant in comparing the incidences of diuretic-intractable ascites and AKI as well as the patients’ prognosis.

The existence of such an optimization may be significant both for the entorhinal cortex itself (where a background θ rhythm is believed to play a role in the phase-coding of position information by grid cells [ 3 ]) and in other parts of the brain for which cell assemblies play an essential role in information processing, in that assemblies of intrinsically θ-frequency cells would be able to form much faster than assemblies of other cells.

The adaptation of students may be significant in the first month or even the first 2 weeks, and many special circumstances are encountered during this period.

That larvae remain trapped inside a durable and non-permeable cuticle for some time after maternal death may be significant: even when the mother is dead, resources derived from her are protected inside her cuticle from exploitation by non-relatives (including other species).

Considering that there may be significant differences in the pathophysiological process between HFrEF and HFpEF ( Putko et al., 2021 ), we believe that research on different types of HF is more realistic for exploring personalized treatment plans.

Some previous studies suggested that rumen effects may be significant when there is relatively low variation in hepatic deamination and transamination 7 .

For example, in an individual HCM patient there may be significant differences in amount of LGE identified depending on which greyscale threshold technique is chosen, with a 2SD threshold resulting in a 2-fold greater amount of hyperenhancement compared to a 6SD threshold (Figure 9B ) [ 108 , 111 , 112 ].

Previous studies have noted that points with a sensitivity of less than 20 dB have less effect on the rate of visual field progression.[ 9 ] During the initial stages of glaucoma, the rate of progression correlates with glaucoma severity; however, for severe glaucoma, the rate of progression is low.[ 10 ] Due to the reduction in variability, even a change <5 dB may be significant for eyes with advanced glaucoma.[ 11 ] Point-wise linear regression (PLR) is analyzed based on individual threshold, total, and pattern deviation values.[ 12 ] PLR analyzes focal changes and underestimates diffuse change.

However, recent studies have shown that the activation, migration, and infiltration of immune cells, especially neutrophils, may be significant during the early stages of cerebral ischemia.

Imaging data do not allow us to distinguish confidently between mitochondrial Ca 2+ accumulation and a discrete ‘late’ Ca 2+ influx at the midpiece, but it may be significant that 5 μM 2-APB is reported to slow the export of Ca 2+ from mitochondria [ 46 ].

For instance, hearing loss may be significant in neurofibromatosis Type 2, while thyroid nodules are common in PTEN hamartoma tumor syndrome and DICER1 syndrome.

The results may be significant in the modulation of monocyte activation-caused inflammatory and neurodegenerative diseases. apoptosis acute inflammation cytokines oxidative stress TRPV1 channel pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement yes pmc-prop-pdf-only no pmc-prop-suppress-copyright no pmc-prop-is-real-version no pmc-prop-is-scanned-article no pmc-prop-preprint no pmc-prop-in-epmc yes pmc-license-ref CC BY 1.

A number of studies have previously estimated the time to perform remote and in-person device checks, yielding a wide range of time estimates, suggesting that there may be significant clinic-to-clinic variability [ 14 , 31 - 33 ].