Disability is reported in more than 90% of ET patients who seek medical care and may be significant enough to warrant invasive surgery such as deep brain stimulation (DBS) or thalamotomy ( 21 ).
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In the literature
As per this study finding concern, patient characteristics, including age, leucocyte count, platelet count, inflammatory markers status, hypokalaemia, and blood oxygen saturation, may be significant predictors for developing critical illness SARS-COV-2 patients.
However, considering the short gestation in rats (22.5 days) and mice (19.5 days), and their consequently faster brain development, compared to the relatively long human gestation (280 days), there may be significant differences in the effect of a pharmacological intervention aimed at crucial brain-development-mediating elements such as NMDA receptors.
The reasons for starting the training programme are unknown, but it may be significant that 1654 saw the start of the Russo-Polish war (1654–67), as well as plague outbreaks.
The common ones shared by these two sequences are Cys191/194 and Cys225/228 (data not shown), perhaps suggesting that they may be significant for NO modification.
Nevertheless, it may be significant to consider the results regarding the sample 13247/60 from Russia which is characterized by particularly high Al and Si contents; these elements can stand for the presence of clay minerals that distinguish the geology of the Siberian mine [ 32 , 33 ].
PMT may be asymptomatic if the programmed MTR is low; however, symptoms may be significant if the MTR is programmed relatively high.
21 , 42 Our data now indicate that both type I IFN activity and B-cell activity may be significant pathologic mechanisms in AQP4-NMOSD, but they may not play an equally significant role in MOGAD or SN-NMOSD patients.
These may be significant predictors.
In addition, the urinary ATP reflects the urinary microbial biomass directly post void and there may be significant variation in the urinary biomass at the time of culture secondary to transportation and processing delay.
This study has the following limitations: (1) among the included literature, 9 were retrospective studies and only 2 were randomized controlled studies, with publication bias; (2) preoperative neoadjuvant chemotherapy regiments are inconsistent in all studies, which may affect short-term prognosis and long-term survival of patients, and there may be significant heterogeneity among studies; (3) some included studies did not provide standard deviations, which were estimated approximately by the Hozo algorithm, and there may be outcome measurement bias; (4) the results of long-term prognosis of patients in the included studies are insufficient, and more reports of long-term follow-up results of studies are expected.
Since there may be significant discrepancy between these estimated and corresponding actual distances, the subsequent step of position estimation of each sensor node by triangulation would introduce large errors in the estimated positions.
Conclusions Collectively, our findings are consistent with the view that gene fusions and other SVs may be significant factors in the onset and progression of ovarian cancer.
Previous studies have shown that the variability in the incidence of HTPR may be significant.
There may be significant delays between the irradiation of test films on a brachytherapy unit and corresponding reference films from an external beam linear accelerator (used to provide uniform film dose irradiation) due to practical equipment access issues within a radiotherapy department.
Suspicions that specific variables may be significant confounders were expressed based on established relationships between explanatory and outcome variable, biological plausibility and inhomogeneous distribution at p < 0.1, and were considered as co‐variables in the multiple regression model.
The temperature charac- teristic obtained for the most dilute emulsion of tributyrin, 10,200, is outside the experimental error of the mean and this deviation may be significant.
The apparent contrast between the present study and earlier findings [ 43 ] [ 45 ] may thus suggest that metformin acts (1) on GLP-1 secretion independently of AMPK, as recently reported in studies of hepatic gluconeogenesis [ 47 ], or (2) that there may be significant differences between the impact of acute and chronic activation of L-cell AMPK on a “gut-brain-liver axis”, with the latter acting chiefly to alter cell mass.
Decision-making that is not directly related to BC treatment may be significant for patients.
While environmental and socioeconomic factors such as diet and access to proper healthcare may be significant causes for increased mortality rates associated with PCa in AA men, recent reports suggest that metabolic alterations may also drive the disparity in PCa progression [ 2 ].
This would be the case when the sub-groups show both raised and lowered trait measurements relative to Col-0 thus obscuring the signal even though they may be significant when associated individually.
Therefore, this change may be significant only if prior experience was accumulated.
It is also increasingly being discovered in urban green spaces such as public parks, where the opportunity to encounter and transmit pathogens to humans and companion animals may be significant [ 17 ].
Given that excessive YAP activation has been associated with OA development [ 69 , 70 , 71 ], metabolic abnormalities such as DM may be significant risk factors for OA.
A number of studies have previously estimated the time to perform remote and in-person device checks, yielding a wide range of time estimates, suggesting that there may be significant clinic-to-clinic variability [ 14 , 31 - 33 ].