Barely Significant
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near-significant

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Listed by Otte et al. (2022)

In the literature

Association between emotion regulation distress ratings and resting and task HRV The correlational analyses on the relationship between emotion regulation and resting HRV indicated a significant (acceptance) and near-significant (reappraisal) negative association between distress ratings (self-reported) and resting HRV for both ER strategies, but did just not remain significant after FWE adjustments (Table 1 , first column).
Following FDR correction, we identified multiple near-significant and significant associations ( q < 0.25 and 0.1, respectively; Extended Data Fig. 9b,c and Methods ), particularly when evaluating features from the immune activation/exhaustion and wound healing clusters (dedifferentiated TI-1 in PD-L1 TPS ≤ 1% q = 0.23; immune-activated M-2 in PD-L1 TPS ≤ 1% q = 0.16; macrophage/monocytes in PD-L1 TPS ≥ 50% q = 0.06; hMono3 in PD-L1 TPS ≥ 50% q = 0.11).
Nonsynonymous somatic mutations in H-FLACs were compared with a panel of 37 mutated genes in LUADs, as these genes displayed significant or near-significant mutation frequencies in 405 LUAD cases, and the data for this gene panel is available at TumorPortal ( http://www.tumorportal.org/tumor_types?ttype=LUAD ), hosted by the Broad Institute of MIT and Harvard (Cambridge, MA, USA).
The comparison of PSG sleep parameters between the two groups revealed significant differences: for macrostructure, REM sleep latency was longer in iRBD patients compared to HCs, as well as the time spent to reach the first epoch of NREM sleep stage 1 (N1), with the difference in sleep onset latency (SOL) to NREM sleep stage 2 (N2) being near-significant; for microstructure, the density of REMs and the number of arousals in REM sleep were higher in iRBD patients than in HCs.
The near-significant difference in the volume ratio compared to the significant difference in overall and intra-cellular transverse relaxation times might be the result of intrinsic lower effect size compared to measurement error, but might potentially indicate the secondary effects of structural changes ( 51 ) following biochemical alteration ( 52 ).
In contrast, near-significant increases in risk for gallbladder cancer were observed for gallstone presence with the FEN1 -69G > A GA (OR = 2.3, 95% CI = 1.5–3.5) and the FEN14150G > T GT (OR = 3.7, 95% CI = 1.4–9.8), whereas significant increases in association for gallbladder cancer were observed for gallstone presence with the FEN1 -69G > A GG (OR = 6.8, 95% CI = 2.1–28.31) and the FEN14150G > T GG(OR = 7.2, 95% CI = 2.2–20.2).