Impact of body habitus and renal function on biodistribution Uptake by healthy tissues (%IA/cm 3 ) was inversely related to weight, LBW, and BSA, with significant to near-significant correlations for parotid, liver, and blood (Table 4 ).
The significance level was set at P < 0.05, and values of P ranging from 0.05 and 0.1 included were considered as near-significant trend 57 .
However, we found a near-significant effect of cTBS in the FP2 trials in the dictator game but not in the generosity game.
Pesticides remained significant (or in one case, near-significant) in each model.
Injection of AAV2.sIL17R resulted in sIL17R protein expression, no change in retinal Il17a transcripts, and a near-significant reduction in Il6 ( Figure S1C–E ), supporting sIL17R expression in AAV2.sIL17R- but not in AAV2.EV-treated eyes.
For significant or near-significant interactions, exploratory pairwise contrasts between treatment conditions were assessed using estimated marginal means.
In all four countries, receipt of partial or complete ANC was not significantly associated with higher odds of immediate breastfeeding relative to those who did not attend ANC, though there was a near-significant negative trend amongst Guatemalan women receiving partial ANC (OR = 0.64 [95% CI: 0.41–0.99]).
In the age groups analysis, for the first age comparison (i.e., age above and below 40 years), only ICP showed a significant difference ( p = 0.048) between the two groups, with AMP having a near-significant p -value of 0.065227, as depicted in Table A3 of Appendix A .
Using the same logistic mixed effects models from Study 1, we obtained the following relevant significant or near-significant 10 main and interaction effects: (1) Language; (2) Canonicity; and (3) Language × Canonicity.
Significant or near-significant enrichment for genes regulated by Myc, DNA repair, mTORC1 signaling, PI3K–Akt–mTOR signaling and protein secretion in all three gene sets was found (Fig. 6b ), identifying these pathways as potential regulators of 5′-C transcript metabolism.
Descriptive tests between the experimental and demographic measures revealed a trend in correlation across participants between age and MWP score (Pearson’s r = − 0.38, p = 0.058), suggesting a near-significant decline in mindwandering tendency with advancing age [ 23 ].
Hence, six GWAS studies were surveyed to find the co-located significant GWAS signals and near-significant GWAS signals with MQTLs based on the common bean genome [ 78 , 79 , 80 , 81 , 82 , 83 ].
Importantly, the strong correlation between class 1 integrons ( int I1) and flo R, alongside near-significant associations with cml A and ere A, reinforces the role of integrons as major drivers of multidrug resistance dissemination in poultry-associated Salmonella .
The near-significant trend toward more effusions with CB mirrors cohort signals of increased serous effusions/readmissions in crossed constructs, possibly related to bar trajectories, contact points, and drainage pathways ( 31 - 33 ).
Significant or near-significant findings discussed below are based on the FDR-adjusted p-values (q-values).
Valencian Community, Cantabria and Navarre showed significant or near-significant increases after the intervention (Beta intervention).
This confound is unlikely to spuriously produce statistically significant proportional recovery relationships out of nothing, since real data should have lower measurement error variance than our simulations, but could push near-significant proportional recovery estimates into statistical significance.
Previous cohort studies have reported a statistically significant decreasing trend with greater alcohol intake among drinkers for diffuse large B-cell lymphoma ( Lim et al , 2007 ; Troy et al , 2010 ), and no significant trend for Hodgkin lymphoma, follicular lymphoma, plasma cell neoplasms or any other non-Hodgkin subtype examined ( Lim et al , 2007 ; Kanda et al , 2010 ; Troy et al , 2010 ), although one study found a near-significant decreasing trend for plasma cell neoplasms ( Troy et al , 2010 ); comparable results from case–control studies were generally consistent with these findings ( Morton et al , 2005b ; Besson et al , 2006a , 2006b ).
Of interest is a near-significant association with accidents occurred with respect to exceeding the weekly rather than daily limits, suggesting that the in-the-event levels of consumption typically associated with injuries did not significantly increase the risk of accidents unless they were consumed often enough to yield a volume of intake that exceeded the weekly drinking limits.
There was a significant increase in mRNAs encoding IFN γ, IL2 , IL10 , IL1A , and TBX21 (Figure 1 ), with a near-significant increase seen in IL4 (Figure 1 ) and TNFA (data not shown) mRNAs.
Regarding the potential impact of administered AAs on the expression of selected transcripts, metabolites, and the microbiota, we failed to identify significant differences between groups, though a few near-significant trends were observed for SLC7A7 ( y+ LAT1 ) and OCLN transcripts in the Peyer’s patch.
For the multivariate analysis, variables were selected that, in the univariate analyses, showed a significant or near-significant effect on the dependent variable, in such a way that the SPV (subjects per variable) index was greater than 15.
The analysis showed statistically significant increases in asthma hospitalization with increases in ozone for the DT air mass for lags of 1 to 5 days, with near-significant increase for a lag of 0 days.
Regarding the borderline significance of CRP ( p = 0.067), the post-hoc power evaluation indicates that this near-significant trend is likely a reflection of the inherent biological variability of inflammatory kinetics in severe UTIs, rather than an underpowered sample size.
Between-group differences remained significant after age-adjustment (Supplementary Material C Tables 1–2), which additionally revealed a significant (profile 1 < 3) and near-significant (profile 1 < 2) difference in indirect effect for negative self-beliefs.