“near-significant”

In the present study, the absence of enhanced performance of prebiotic groups, as well as their near-significant reduction in BW on day 14, may reflect mismatches between substrate availability and microbial adaptation: in the sequential GXOS diet group, early GOS exposure may have primed communities that then required additional time to adjust to XOS, delaying microbial shifts and subsequent XOS-mediated performance benefits; conversely, in the XOS group, introducing XOS after seven days of the basal diet may have disrupted the stabilising microbial community, requiring a reorganisation of established cross-feeding networks and imposing short-term metabolic costs that limited growth efficiency.

Interestingly, while no statistically significant predictors were found for the future perspective subscale, the near-significant negative association of chest pain invites discourse about the interaction between unresolved physical symptoms and patients’ psychological well-being.

S1 B ), and a near-significant correlation was found between LPO and TH expression.

In all statistical analyses, differences were taken to be significant at p ≤ 0.05, while 0.05 < p ≤ 0.10 were considered near-significant trends. 3.

Return of bowel function, as indicated by passing of flatus, was earlier in patients of the combination group significantly when compared to bupivacaine alone, and near-significant when compared to the lignocaine-only group.

The similar findings of decreased TXNIP SAT expression in both O-GDM and O-T1DM (although only near-significant for O-T1DM) lend added credibility to our results, but studies of TXNIP expression in SAT are scarce, and we cannot exclude that our findings could be part of an as yet unknown pathogenic mechanism.

A two-step approach will first identify individually significant and near-significant associations with outcome measures, and then simultaneously fit these variables in a multiple predictor model.

Per-protocol analysis for Modulen group ( n = 11): Per-protocol analysis of 11 patients who completed eight weeks of nutritional treatment confirmed significant improvements in CDAI, IBDQ, and a near-significant improvement in total symptoms score.

However, exploratory post-hoc comparisons between study visits showed significant or near-significant differences between GSRS-IBS scores between study visits at baseline or before stimulation versus those conducted at the 9 or 12 month follow-ups (see Figure 1 ).

However, sleep education (SMD −4.31, 95% CI −9.78 to 1.15), or relaxation (SMD −2.44, 95% CI −5.98 to 1.09) did not show significant or near-significant differences with the wait-list ( Table 2 , Figure 3 , Supplementary Figures 3–9 , Supplementary Table 27 ).

EDA and antidepressants A cross-sectional study by Weckowicz [ 81 ] found GSR was a near-significant predictor of psychotherapy and drug therapy in depressed patients.

The reported use of GRE during the diagnostic workup was a significant predictor of reduced recurrence rates, and was a near-significant predictor of improved remission.

Additionally, the study reported a significant reduction in the mean percentage of fibrous tissue within the wounds, along with a near-significant increase in granulation tissue [ 165 ].

Furthermore, go- relative to no-go training to alcohol caused a near-significant increase in a psychophysiological index of approach motivation (frontal EEG asymmetry) to alcohol pictures ( Bowley et al., 2013 ).

While the direct substrates of mutant ODGHL (ɑ-ketoglutarate and succinyl-CoA) were not detected within the screen, we did detect near-significant changes in several metabolites that are closely related to wild type OGDHL functions as shown in the Fig. 3c schematic.

The near-significant post-treatment p -value suggests a biological trend, which could be related to hypoxia, necrosis, or persistent inflammatory responses that are more common in advanced tumors.

Additionally, the near-significant p-value of 0.09 for U-Net + Inception V3 versus U-Net + VGG16 indicates a slight but not statistically significant difference in performance, suggesting their potential equivalence in effectiveness.

Tabulation of incidental lesions (i.e., combining lethal and non-lethal lesions) revealed a complex set of significant and near-significant changes caused by each of the two agents, in some cases absent, or even opposite in direction, in one of the two sexes.

Using the multivariate statistical regression, we identified 19 variables with statistically significant or near-significant differences through univariate analysis.

Similarly, patients with cholesterol ≥ 200 mg/L had elevated hs-CRP levels in PDR (11.24 ± 17.28 mg/L), while those with cholesterol < 200 mg/L showed lower values (4.48 ± 3.63 mg/L), with a near-significant p-value of 0.060 ( Table 3 ).

We did not find a significant correlation of PRAME with chromosome 3 status or BAP1 expression in either cohort, and we saw a borderline correlation with 6p gain in the TCGA disomy 3 subcohort and a matched near-significant correlation in the LUMC disomy 3 subcohort.

We found near-significant or significant differences of total lysate β-Arrestin1 and ARHGAP21 between PTEN-expressing and -deficient cells [Caco-2 vs Sh PTEN ( Figure 1A,B ) and HCT116 vs PTEN -/- cells ( Figure 1—figure supplements 1 and 2 )].

This borderline result may represent either a true difference undetected due to insufficient power (Type II error) or a chance finding, and should be considered when interpreting near-significant findings.

This near-significant association warrants prospective investigation to clarify directionality.

The coefficient for Mn is −0.5991, with a p value of 0.075, indicating a near-significant negative effect on the inhibition zone, suggesting that higher manganese levels might enhance antimicrobial activity.