Barely Significant
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of borderline significance

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In the literature

Age- and sex-standardized prevalences showed a significant difference for any retinopathy (South Asian 48.3% [95% CI 43.5–53.1] versus white European 37.2% [33.3–41.0]) but not STR (South Asian 17.3% [13.7–20.9] versus white European 12.4% [9.7–15.0] and were of borderline significance for maculopathy (South Asian 14.4% [11.1–17.8] versus white European 8.8% [6.5–11.1]).
The remaining 8/17 studies considered both SUV-based and volumetric parameters (MTV and TLG) [ 29 , 34 , 35 , 37 , 45 , 46 , 47 , 50 ]: volumetric parameters showed a better prognostic value than SUV measure in 5/8 cases [ 34 , 35 , 37 , 47 , 50 ], with SUVmax of borderline significance and at univariate analysis only (in the studies by Nowak et al. and Klabatsa et al.), or significant at univariate analysis only (as reported by Doi et al.), or with totally no prognostic prediction power (as found by Lee et al. and Pavic et al.); SUVmax remained the only significant prognostic factor at multivariate analysis (if histology variable was excluded) in one study, when compared to MTV and TLG [ 46 ]; all PET parameters were significantly associated with prognosis in the remaining two studies [ 29 , 45 ].
There was also no strong evidence for variation in the vitamin D allele score–BMI association by average BMI of the study (≤25 kg/m 2 versus ≥25 kg/m 2 ), although for the synthesis score the meta-regression coefficient was of borderline significance ( p meta-regression = 0.053, Figure S8 ; p meta-regression = 0.78 for metabolism score).
Similarly to the univariate results, sβ 2 m levels > 2.0 mg/L were an independent adverse prognostic factor of borderline significance in the multivariate analysis of patients with advanced stages, including all the IPS factors ( Table 4 ; see also footnote) along with stage IV, lymphopenia and leukocytosis (protective!!) (hazard ratio (HR) 1.44, 95% CI 0.94–2.21, and p = 0.098; Table 4 ).
Indeed, investigating the association between influenza infection and vaccination during pregnancy and autism spectrum disorder (ASD) risk in a cohort study of 196,929 children born at Kaiser Permanente Northern California, Zerbo and colleagues [ 16 ] found that influenza vaccination anytime during pregnancy was not associated with ASD risk (the adjusted HR was of borderline significance: 1.10; 95% CI 1.00–1.21).
Influenza Vaccinations for All Pregnant Women? Better Evidence Is Needed.
Int J Environ Res Public Health · 2018 · PMC6164291