After also including age, height, walking speed, calcium intake, smoking status, and use of bisphosphonates and glucocorticoids as covariates, only aBMD of the radius remained significant, whereas aBMD of the hip and lumbar spine were of borderline significance (Table 1 ).
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“of borderline significance”
In the literature
Although of borderline significance, LTE 4 concentrations remained elevated in T2-high versus T2-low participants, having excluded those on montelukast (LTRA).
Although this finding was of borderline significance, it concurs with Tones et al .
As the significant findings obtained with c.−436C>A were limited to the assumption of an additive inheritance mode, the association of c.334+46C>T being of borderline significance was not pursued further.
38 A history of diabetes was significantly associated with HFpEF, and a history of hypertension was of borderline significance, although these relationships did not persist after adjustment for multiple variables.
Inverse associations with 138, 156, 180, 187 and 201 were of borderline significance.
In our study, the subgroup of women with persistent HPV infection, ever use as opposed to never use of OC, was related to a decreased risk for CIN3+ of borderline significance and a statistically significantly decreased risk was found with 4 or less years of OC use.
Though the trial found a trend towards fewer cardiovascular outcomes, favouring candesartan, it was moderate and of borderline significance.
Age- and sex-standardized prevalences showed a significant difference for any retinopathy (South Asian 48.3% [95% CI 43.5–53.1] versus white European 37.2% [33.3–41.0]) but not STR (South Asian 17.3% [13.7–20.9] versus white European 12.4% [9.7–15.0] and were of borderline significance for maculopathy (South Asian 14.4% [11.1–17.8] versus white European 8.8% [6.5–11.1]).
In the current study, BRCA1 methylation and survival association was of borderline significance ( P log-rank = .065).
Potential interactions between all predictors in the model and variables excluded from the model but of borderline significance were also tested.
In the upper panel, the NAET risk significantly increased with woodworking (adjusted OR 9.25, p = 0.028), and was of borderline significance for leatherworking.
The remaining 8/17 studies considered both SUV-based and volumetric parameters (MTV and TLG) [ 29 , 34 , 35 , 37 , 45 , 46 , 47 , 50 ]: volumetric parameters showed a better prognostic value than SUV measure in 5/8 cases [ 34 , 35 , 37 , 47 , 50 ], with SUVmax of borderline significance and at univariate analysis only (in the studies by Nowak et al. and Klabatsa et al.), or significant at univariate analysis only (as reported by Doi et al.), or with totally no prognostic prediction power (as found by Lee et al. and Pavic et al.); SUVmax remained the only significant prognostic factor at multivariate analysis (if histology variable was excluded) in one study, when compared to MTV and TLG [ 46 ]; all PET parameters were significantly associated with prognosis in the remaining two studies [ 29 , 45 ].
Similar caution must be advised for the interpretation of borderline significance because of multiple testing (ΔCPO and NT‐proBNP).
Eradication of HCV infection was suggested as a risk factor, although of borderline significance.
There was also no strong evidence for variation in the vitamin D allele score–BMI association by average BMI of the study (≤25 kg/m 2 versus ≥25 kg/m 2 ), although for the synthesis score the meta-regression coefficient was of borderline significance ( p meta-regression = 0.053, Figure S8 ; p meta-regression = 0.78 for metabolism score).
Those who performed rotating shift work (with and without nights) had a small increase in risk for SGA compared to daytime workers that was of borderline significance (OR 1.09, 95% CI 1.00–1.18).
The relationship between SES and mental health (MHI-5) was significant at the individual level and of borderline significance at the area level.
Two other recent studies have shown increased risks of wheeze of borderline significance in relation to increased residential proximity to surfaced roads in Ethiopia[ 2 ] and living within 20 m of a main street in Switzerland[ 3 ].
uPA/PAI-1 and tumor grade were of borderline significance for OS.
The independent prognostic effect of IFP for recurrence and survival was strong, whereas the independent prognostic effect of tumor hypoxia was of borderline significance and was limited to patients without nodal metastases [ 9 ].
Multivariate analysis showed an odds ratio of 1.5 towards better eradication rate with concomitant regimen of borderline significance (OR 1.5, 95% CI 0.9-2.8).
Similarly to the univariate results, sβ 2 m levels > 2.0 mg/L were an independent adverse prognostic factor of borderline significance in the multivariate analysis of patients with advanced stages, including all the IPS factors ( Table 4 ; see also footnote) along with stage IV, lymphopenia and leukocytosis (protective!!) (hazard ratio (HR) 1.44, 95% CI 0.94–2.21, and p = 0.098; Table 4 ).
Indeed, investigating the association between influenza infection and vaccination during pregnancy and autism spectrum disorder (ASD) risk in a cohort study of 196,929 children born at Kaiser Permanente Northern California, Zerbo and colleagues [ 16 ] found that influenza vaccination anytime during pregnancy was not associated with ASD risk (the adjusted HR was of borderline significance: 1.10; 95% CI 1.00–1.21).
The pooled effect estimate was similar for cohort and case–control study design (0.67 and 0.60 respectively), although it was of borderline significance for case–control study design.