This observation may reflect a reduction in systemic inflammatory activity, as indicated by the hs-CRP/albumin ratio and NLR, which showed a trend toward post-treatment decreases.
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Higher M2 TAMs infiltration was associated with deeper tumor invasion (pT) and showed a trend toward advanced pTNM stage.
The spirulina pretreatment showed a trend toward an improved lipid profile in the HFD + IR condition, where TC was significantly less prominent.
Second, higher levels of ubiquinone showed a trend towards an association with higher all-cause mortality risk, which reached statistical significance only in the unadjusted model.
Patients with a Sister Mary Joseph nodule showed a trend toward better survival outcomes.
Compared with MTAP wild-type tumors (median 63 years, IQR 55–69), patients with MTAP deletion showed a trend toward older age; however, this difference did not reach statistical significance (Wilcoxon rank-sum test, p = 0.069).
In a prespecified exploratory analysis of the CD16A-158 polymorphism (V, high-affinity; F, low-affinity), patients with the CD16A-158FF genotype showed a trend toward improved OS with margetuximab compared with trastuzumab (median, 23.6 vs. 19.2 months; HR, 0.72; 95% CI, 0.52–1.00).
In groups 6–9 and 10–13, as fiber content increased, N 1 and N 2 showed a trend of initial increase followed by a decrease.
In the ordination plot, samples from Group C and Group M showed a trend of differential distribution along the coordinate axes.
As shown in Figure 2 , as the initiator amount increased, the gelation time of the supramolecular gel gradually shortened, while the viscosity showed a trend of first increasing and then decreasing.
Tumor-related factors: Tumor ulceration and necrosis showed a trend toward worse survival but did not reach statistical significance (HR = 0.52 for absence vs. presence; 95% CI: 0.23–1.16 and p = 0.112).
Paired comparisons showed a trend toward lower thresholds with CE-Chirp, although statistical significance was not reached due to the limited sample size.
Mice treated with resveratrol showed a trend toward increased time and distance on the rotarod compared to the D-gal-induced aging mice ( Figure 1 L,M).
Results The trial (N = 260) showed a trend towards fewer major renal or cardiovascular events in the integrated care group, particularly fewer heart failure hospitalisations.
In the FLT3 m subgroup ( n = 66), oral azacitidine improved relapse-free survival (RFS) and showed a trend toward improved OS [ 15 ].
Among the variables included in the model, nitrous oxide use showed a trend toward association with anxiety reduction.
The cooking loss of the samples showed a trend analogous to that of drip loss ( Figure 4 B).
Nevertheless, performance metrics consistently showed a trend toward higher sensitivity, specificity, and accuracy for contrast-enhanced MRI across readers with different levels of experience.
Patients with impaired CAR showed a trend toward shorter ICU length of stay (median 18.9 [8.8–37.0] vs. 32.9 [18.5–64.2] days) and higher 30-day mortality (36% vs. 15%), although these differences did not reach statistical significance.
After adjustment, aberrant p53 showed a trend toward increased mortality (HR: CSS 3.56; OS 2.52), and low Wnt3 tended to be associated with poorer CSS (HR 2.59), whereas neither β-CTN index was prognostic.
Although FGFR3 -mutant tumors in our cohort showed a trend toward improved survival, this association did not retain independent significance in multivariable models, likely reflecting the strong correlation between FGFR3 activation and favorable clinicopathological features such as lower grade and stage and co-occurrence with protective alterations including STAG2 .
It can be seen from Figure 3 d that within the range of 7.5 g to 17.5 g of boric acid dosage, the viscosity showed a trend of first increasing and then decreasing, reaching a peak at 12.5 g (104 mPa·s).
In contrast, siRNA-mediated STRIP1 knockdown showed a trend toward increased expression of hypertrophic marker genes compared to control siRNA, both under basal conditions and following PE or ISO stimulation, although these changes did not reach statistical significance ( Supplementary Figure S3 ).
OS also showed a trend toward improvement in the IHLRT+ group, although this did not reach statistical significance (31.8 vs. 24.2 months; 95% CI: 21.0–42.7 vs. 10.7–37.7; p = 0.087) ( Figure 1 B).
POD activity showed a trend of initial decrease followed by an increase.