“showed a trend”

Similarly, while CFU-E colony numbers showed a trend of increase with SRT2104 treatment (no SRT2104, 27.1%±4.7%; SRT2104, 35.7%±8.3%), this difference also did not reach statistical significance ( Fig. 4A ).

Aerobic exercise (AE) (SMD = −0.64, 95% CI [−1.30, 0.02]) showed a trend of superiority over the remaining exercise interventions, although the difference was not statistically significant.

The level of consciousness at hospital arrival showed a trend towards more obtunded or unconscious patients in the SÖSR group, although the difference was not statistically significant ( P = 0.058).

In the independent GEO cohort GSE39582 , DMBX1 expression showed a trend toward higher levels in colorectal cancer tissues compared with normal mucosa, although the difference did not reach statistical significance (Wilcoxon rank-sum test, p = 0.083).

Under all three breathing modes, the velocity of airflow from the lower edge of the epiglottis to the pharyngeal cavity showed a trend of decrease (Fig. 16 ).

A two-way ANOVA analysis revealed no significant interaction between outcome and sampling time (Richness, p = 0.707; Shannon, p = 0.543), although both indices showed a trend toward increased diversity from D1 to D7 ( Figure 3 C).

Moreover, GOT1 siRNA showed a trend of increased aspartate release in high, but not in low glucose conditions (Fig. 3 d).

Sarcoma showed a trend toward an increased risk; however, this association did not reach statistical significance ( P = 0.051) (Table 3 ).

We noted that Xist expression showed a trend towards increased expression in Dy 3K /Dy 3K females, but it was significantly increased in male mice (Supplementary Fig. 4 b), possibly hinting at a role beyond X-chromosome inactivation in dystrophic pathology.

While the Vaccine + OTA + 38352 group showed a trend of reduced lesion scores compared to the Vaccine group, the differences were not statistically significant ( Fig.

In terms of both the tumor-to-blood and tumor-to-muscle ratios, [ 89 Zr]Zr-DFO-PR15-7 showed a trend toward greater tumor accumulation in the GUCY2C-positive xenograft model when compared with the other 3 control groups (Supplemental Fig. 5E).

Although no significant differences were detected, both HY03 and COPD iALI showed a trend toward increased expression of goblet cell and basal cell markers upon infection.

CAR T cells pretreated with 10mM inosine for 48 hours showed a trend toward increased cytotoxicity after 24-hour coculture compared with untreated cells ( Figure 3 I-J).

In the longitudinal descriptive analysis, the mean change from baseline in the QLQ-C30 global health status/QoL showed a trend toward improvement for the nivolumab plus gemcitabine–cisplatin arm, whereas that of the gemcitabine–cisplatin alone arm remained stable up to week 24, after which the sample size fell below 10 ( Figure 3 ).

Cox regression models showed a trend toward higher fracture hazard in T1DM, although statistical significance was not reached, likely reflecting the modest number of fracture events.

The comparison of CGM parameters between CGM alone users and HCL system users showed a trend toward improved glycemic control in the HCL group, although most differences were not statistically significant ( Table 4 ).

(2025) [ 132 ]( NCT05227846 and NCT05984303 ) found that higher doses or multiple administrations of MSCs elicited stronger immunomodulatory effects and showed a trend toward greater improvement in clinical metrics.

VOCs in region B showed a trend of increasing initially and then decreasing during boiling.

Higher alcohol intake showed a trend toward reduced AD risk.

Principal component analysis (PCA) also showed a trend toward spatial separation, indicating molecular heterogeneity between the groups; however, due to limited sample size and within-group variability, the 95% confidence intervals partially overlapped, and the separation did not reach statistical significance ( Figure S7 G ).

Macrophages treated with SMase-derived EVs also showed a trend of TNF-α reduction compared to UT EVs ( Figures 6 F and 6G).

STS718 treatment showed a trend in reducing the levels of proteinuria compared with vehicle-treated group, though statistically significance did not reach ( Figure S3 B-C ).

Both biomarkers showed a trend of progressive increase from CN A− to CN A+, MCI A+, and AD A+, but the group differences were more pronounced for serum β-synuclein.

In this study, we first explored the expression of 8 members in the PSMA family in different cancer types through pan-cancer analysis and discovered that PSMA1-7 showed a trend of overexpression in BLCA.

The expression and m6A modification levels of AFAP1-AS1 in PC tissues and cell lines were significantly higher than those of normal controls and showed a trend of increasing with tumor stage progression, and this expression pattern was closely associated with poor patient prognosis.