Analysis of CD107a and CD127 in PBMCs from patients with breast cancer showed a trend, but not statistically solid differences, towards lower values of IL-7R expression on CD4+CD107a+ T-cells [27] .
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The reproduction numbers showed a trend similar to the effective contact rates, with a clearly decreasing trend over time, suggesting that the epidemic was under control as early as mid-March (see Figure in Text S3 ).
In contrast to prediction, across these common sites, HIF-2α showed a trend to greater maximum enrichment than HIF-1α ( Fig. 4 ).
PGE 2 concentration in culture media at day 7 was significantly increased by IL-1 β and OSM and treatment with both tepoxalin and its metabolite showed a trend towards dose-dependent reduction of PGE 2 production.
This was not observed in Fto I367F mice although homozygotes showed a trend to towards reduced food intake on both standard and high-fat diets.
Comparing responses of the four sterilely protected monkeys with the six unprotected animals in the DNA/Pox and Ad/Pox groups, only the MSP1 ELISA and ELISPOT showed a trend toward higher values in the sterilely protected monkeys but this was not statistically significant (data not shown).
The two small studies that reported this outcome showed a trend favoring infliximab but failed to reach statistical significance ( Probert et al 2003 ; Järnerot et al 2005 ).
While these criteria were believed to be sufficient at the time of the trial, many subjects had significant CVD risk and/or were found to have had a prior CVD [ 35 , 71 ].The CEE+MPA portion of the WHI trial was stopped early in 2002 because accumulating data showed a trend toward increased breast cancer which crossed a prespecified stopping point; thus, the benefit/risk ratio for the treatment was believed to have shifted from positive to negative [ 71 ].
Arylesterase activity Results plotting phenyl acetate hydrolysis (arylesterase activity) versus POase activity showed a trend toward separating individuals into the three functional genotypes ( Figure 4 ), but did not yield as clear-cut a distinction among the three functional genotypes as did the plot of POase versus DZOase.
After copy number correction, the total SNCA concentration in the mouse blood showed a trend for the reduction in the PD risk-associated Rep1-261 bp animals, but the variability, in particular within the Rep1-259 bp genotype, was large (Fig. 7 B).
WT-expressing cells showed a trend to a decrease in migration on all matrix proteins in 0.5% serum (data not shown), though only collagen II showed a significant decrease ( p < 0.0001).
Multivariable analysis controlling for severity of illness with the APACHE score and underlying diseases with the Charlson index showed a trend toward more deaths associated with infection with MDR Acinetobacter than with infection with susceptible Acinetobacter , but the difference was not statistically significant (relative risk 2.6, 95% CI 0.3–26.1) ( Table 3 ).
Treatment of HT29 cells with 5-FU (0, 6.25, 12.5, 25, 50 μM) for 72 h showed a trend of diminished expression of MMP7, but it significantly down-regulated ERβ protein levels only when given at 50 μM.
Amplitude A as an adverse prognostic variable showed a trend for overall survival as well.
Although SK2-treated animals showed a trend of increase in open arm exploration in stress and CORT-treated animals, planned comparison between the groups failed to reach statistical significance ( Figure 7A ; p > 0.2).
HbA1c level, and weight both showed a trend toward improvement following the intervention but results were not statistically significant.
The Canadian study [ 21 ] found significant trends only in men, while the Scottish study [ 18 ] showed a trend in the opposite direction.
For instance, the total intensity of AOMs on the PhyloChip showed a trend of R1 (ERY-H 2 O) <R2 (ERY) <R3 (control), indicating that the specific ammonium oxidizing capacity and antibiotic resistance of AOMs were in a reverse order of R1 (ERY-H 2 O) >R2 (ERY) >R3 (control).
However intracellular cytokine staining on mucosal lymphocytes showed a trend toward an increase in CD8+T cells secreting TNF and IL-2 in CCL27 co-immunized macaques, levels greater than those observed in infected animals.
The ELISPOT assay utilized DR4-restricted peptides predominantly and showed a trend for greater specificity among DR4+ individuals.
Patients treated for recurrent meningioma showed a trend toward decreased progression-free survival compared with patients treated with primary therapy after subtotal resection.
As expected, most MA datasets showed a trend towards increasing LLS as correlation values increased.
An earlier study also showed a trend toward a decrease in RV end-systolic and end-diastolic areas with oral bosentan treatment without achieving statistical significance, 24) which is in agreement with the results of the current study.
Compared with adult, senior diabetic burn patients showed a trend toward an increase in wound infections, bacteremia, and sepsis.
In both our adult and paediatric cohort, yearly evaluation of immune status showed a trend towards improvement.