Although the primary outcome did not differ, the methylprednisolone group showed a trend toward lower early postpartum inflammatory levels, indicating a potential advantage in anti-inflammatory regulation.
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3.7 months) and showed a trend toward overall survival benefit (12.9 vs. 8.9 months), with an objective response rate of 30.8% and a manageable safety profile ( 10 ).
No significant correlation was found between individual comorbidities and infection risk, though multiple risk factors showed a trend toward increased infection risk.
For spontaneous alternation (Y-maze), REST overexpression showed a trend toward improved scores for the P301S mice ( Fig. 3B and C ).
Heads of departments/professors also showed a trend toward opposition, though this was not statistically significant (aIRR 1.16, 95% CI 0.997-1.34, p = 0.055).
Notably, the no-prophylaxis cohort showed a trend toward better outcomes, possibly reflecting reduced microbiota disruption or lower selective pressure for resistant organisms.
36.9%, p = 0.007) and showed a trend towards higher utilization of CRRT.
Furthermore, tranilast treatment showed a trend towards reducing plasma IL-1β levels on days 3, 7 and 14 after PPE infusion; however, the differences were not statistically significant ( Fig.
Conversely, the beneficial effect of SSRF was higher in the subgroup without pulmonary injury (HR 0.193, 95% CI 0.067–0.557, p = 0.002) than in the subgroup with pulmonary injury (HR 0.293, 95% CI 0.053–1.607, p = 0.157), the latter of which again showed a trend but did not reach statistical significance.
lagopus seedling leaves showed a trend of first decreasing and then increasing with decreasing temperature ( Figures 1A, C ).
While the 100 mg/kg dose showed a trend toward reduction, the 150 mg/kg regimen yielded a statistically significant decrease in lung viral titers compared to the vehicle control.
Even though the OS, DFS, and GRFS showed a trend in favor of the PTCY cohort, there was no statistically significant difference in these outcomes at 12 months after transplant for the PTCY and CNI-MTX cohorts, perhaps due to the limited sample size.
Reparixin showed a trend toward limiting disease progression as an add-on therapy in COVID-19 severe pneumonia ( NCT04878055 ); the results of the ARDS clinical trial have not yet been reported ( NCT05496868 ) [ 190 ].
Notably, PBMCs from patients with progressive disease also showed a trend for higher proliferation, possibly reflecting intrinsic differences in proliferative potential and anergy ( Caligaris-Cappio, 2014 ; Haselager et al., 2023 ; ten Hacken et al., 2019 ).
Although POD activity in the M8 treatment (56.22 U g −1 FW) showed a trend of recovery toward control levels, it remained statistically comparable to both the control and intermediate treatments based on post hoc letter groupings.
For example, RFX-NS showed a trend towards prolonged T max , elevated C max , and an approximately 1.29-fold increase in AUC.
Quantitative assessment of spared white matter showed a trend toward greater preservation at all distances from the injury epicenter in animals receiving the combined therapy versus untreated SCI controls, although these differences did not reach statistical significance ( Figure 3 D). 3.4.
Fecal sIgA (mg/g stool) showed a trend toward higher levels in the intervention group and lower levels in the placebo group, with one pre-specified subgroup demonstrating a significant difference in change-from-baseline (intervention +1.12 mg/g vs. placebo −1.02 mg/g).
Consistent with these findings, MRPL9-knockdown cells showed a trend toward S-phase arrest (not statistically significant), while LPCAT1-knockdown cells exhibited a significant G2-phase arrest ( Figure 8 I).
In our study, stratification by FIGO stage showed a trend toward worse prognosis for G-EAC compared with usual-type endocervical adenocarcinoma, though not statistically significant, likely due to limited follow-up and sample size.
In response to T COVID , MSCs showed a trend to elevated levels of IL-6 ( Figure S3a , mean 23.337 ± SEM 24.725, n = 3), IL-1β ( Figure S3b , mean 27.877 ± SEM 25.697, n = 3) and tumor necrosis factor (TNF)-α ( Figure S3c , mean 5.365 ± SEM 4.581, n = 3) compared to coculture with T unstim (IL-6 mean 5.15 ± SEM 4.917, IL-1β mean 7.4 ± SEM 6.521, TNF-α mean 2.263 ± SEM 0.055) ( Figure S3a–c ).
HRQoL data from the ASCEMBL trial comparing asciminib to bosutinib in patients with CML-CP previously treated with ≥2 TKIs showed a trend of improvement in the MDASI-CML and EQ-5D-5L scores in the asciminib arm, including fatigue, whereas there was a worsening of gastrointestinal symptoms in the bosutinib arm.
Again, the group with high p-tau217 and normal PET group did not reach statistical significance but showed a trend towards significant association with DESH, suggesting that these differences may be dictated by plasma biomarker factors more so than amyloid PET elevation, but the variance was also greater in the p-tau217 analyses.
STEC/ETEC hybrids exhibited significantly higher cytotoxicity compared to ETEC mono-pathotypes, and they showed a trend toward increased cytotoxicity compared to STEC isolates.
Notably, total IgE levels showed a trend toward elevation in the consolidation group compared to the non-consolidation group, although this difference did not reach statistical significance.