More importantly, contrast sensitivity loss for 0.5 cpd showed a trend with thinning of the neural rim.
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In the literature
The HDRS score showed a trend towards an improvement at follow-up (with a moderate effect size); a dysthymic disorder, evaluated by the SCID-I, was found in only one patient at follow-up, vs. 5 at baseline.
[103] Compared to valsartan alone, the LCZ696 (Neprilysin, the zinc-dependent metalloprotease that degrades biologically active natriuretic peptides) group had significantly lower NT-pro BNP levels and at 36 weeks, decreased LA size and showed a trend toward improved functional class in PARAMOUNT study.
Tadalafil treatment showed a trend toward reduction, and interestingly, no such effect was evident for the combination therapy ( Fig 7 ).
GCR expression in monocytes and neutrophils showed a trend to be lower in the subjects with CV Failure, but this association did not reach statistical significance.
In seven clinical studies, three showed a trend toward higher compliance rates with rifabutin-containing regimens than with conventional therapeutic regimens [ 15 , 18 , 19 ].
μ CT analysis showed a trend towards decreased bone tissue mineral density in the HS group.
By 45 days, the rmCHI mice also showed a trend towards reduced time spent in target quadrant ( Fig. 4H ).
This is particularly odd given the result that the ERN, when collapsed across sham and prism blocks, showed a trend to increase linearly with error size—which decreased from early to late phases.
Additionally, LV end-systolic diameter (LVESd) was significantly increased after a 12-wk HFD, CD36 deficiency showed a trend to blunt this alteration with no statistical significance.
Gender differences were noted, with female miR-146a– /– mice showing significant differences in survival, while males only showed a trend towards reduced survival ( Supplementary Figure 1a–1d ).
The between-examiner reproducibility assessments showed a trend similar to the intrasession repeatability assessments. 3.5.
Internal validation was provided through exploratory analyses, which showed that decreasing ∆Ct values (i.e., increasing HRG mRNA expression levels) showed a trend for improved clinical benefit (i.e., lower HR) for patients treated with patritumab plus erlotinib compared with placebo plus erlotinib.
Additionally, -1171 5A/6A showed a trend towards protective factor for periodontitis in the recessive model, although the finding was not statistically significant ( p = 0.06).
Our study showed a trend of higher odds of glycemic intolerance in patients with vitamin D deficiency.
Transport to hospital only showed a trend, whereas severity of hypoglycemia or number of episodes showed no predictive value (see table 3 ).
The three latent PFAS variables showed a trend of inverse relationships with each of the antibody concentrations.
Overall, consuming n-3 PUFA through dietary forms primarily showed a trend in TG reductions, while a significant effect was only observed when large amounts of n-3 PUFA were consumed (as observed in Table 2 , ≥ 4 g/day of n-3 PUFA) and the effects of ALA supplementation were highly variable [ 17 ].
Short-term postpartal neonatal parameters showed a trend to lower 1’, 5’ and 10’ minute APGAR scores in PEIC neonates.
For each species, the corresponding dendrogram showed a trend for population clustering according to geographic origin, which is consistent with other studies [ 12 ].
Accordingly, our study showed a trend to a reduction of HbA1c in migrants subgroup treated with vitamin D.
Selectivity of THK5117 Increasing concentrations of FDDNP showed a trend for competition with 3 H-THK5117 for a super-high affinity binding site (picomolar range) and a low affinity site (micromolar range; Additional file 3 a).
Adding 25(OH)D 3 in the presence of PBA enhanced the response of eight 25(OH)D 3 -regulated genes: five ( CAMP , CYP24A1 (OMIM 126065), IL36 , IL37 , TREM1 ) were synergistically induced, with the combined effect of co-treatment greater than an additive combination of individual effects, and three chemokines CXCL7 , and IFNγ-inducible CXCL9 and CXCL10 were all further inhibited by combined treatment, despite the fact that PBA only showed a trend towards inhibition of CXCL9 and CXCL10 during monotherapy ( Fig 4B and Table 2 ).
Hormone therapy showed a trend for superior OS rate.
Patients that died during long-term follow-up showed a trend towards higher initial OPN levels than survivors; strikingly, serum OPN levels at day 3 were significantly higher levels in patients that died during follow-up than for surviving patients (Fig. 5a , b ).