Other research showed a trend for reduced risk of incident cardiovascular disease in men 70 years of age or older with erectile dysfunction [ 20 ], without renal failure.
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The incidences of the two pathologies in the Piemontese breed in the last decades also showed a trend compatible with the case of selection against the recessive phenotype, and this led us to hypothesize the existence of a monogenic determinism similar to what was observed in the other cattle breeds.
[ 8 ] In our study, both MG and MS showed a trend towards improvement during pregnancy and worsening in the postpartum period, which is consistent with the literature.
In this study, BC patients with FGFR1 amplification showed a trend toward poorer outcomes, especially DMFS and LRFS.
Survival analysis for the three treatments stratified by hormone receptor subtype showed a trend favoring eribulin within the TNBC patient subtype compared to gemcitabine [HR (95% CI) 0.82 (0.51, 1.30)] and capecitabine [HR (95% CI) 0.77 (0.43, 1.38)], though it was not statistically significant.
Though any correlation could be detected between bone mineralization, in terms of T -scores, and the serum tryptase levels, the number of vertebral fractures showed a trend towards a positive correlation with the serum tryptase levels in osteoporotic patients with hypertryptasemia suggestive for SM (serum tryptase levels > 11.4 ng/ml; r = 0.239 and P = 0.054).
Tumors formed by Mgrn1 -KO B16-F10 cells had lower mitotic indices, fewer Ki67-positive cells and showed a trend towards smaller size.
The AJCC 8th edition staging system showed a trend to better discrimination, with an AUC of 0.69 (95% CI: 0.52–0.84) compared to 0.61 (95% CI: 0.51–0.73) for the 7th edition.
Indeed, cells supplemented with DHA and DHA + PRO showed a trend to reduction in the concentration of total fatty acids other than DHA, and the concentration of total PUFAs other than DHA was significantly lower in cells supplemented with the fatty acid ( Table S3 ).
The respective TsV-loaded samples showed a trend of superior cell survival rates.
In agreement with this concept, in our study, TGFB1 gene expression showed a trend opposed to those of basophils and monocytes.
The PFS was not significantly different among the 1G or 2G EGFR -TKIs but showed a trend favoring the afatinib group in patients with uncommon EGFR mutation-positive NSCLC.
The Rac1-Q61L mutant showed a trend toward increasing the migration of B16-F10 Control cells, although this difference was not significant ( p = 0.0555).
Cumulative meta-analysis showed a trend toward a null effect as data cumulated by year ( Figure S2 ).
In cells maintained in the presence of α-MSH, CMT-308 showed a trend for reduction in ROS generation, although no significance was reached at any concentration ( Figure 4 D). 3.9.
Tumor necrosis factor alpha (TNF) levels showed a trend to return to basal levels, but the levels were still significantly higher at the end of the recovery period than in unexposed cells ( Figure 5 D, black bars).
However, we found that hypnotics use among the elderly showed a trend towards increased risk of cancer but not significantly (OR/RR, 1.16; 95% CI, 0.92–1.47; I 2 = 84%).
The α-synuclein-expressing strains showed a trend towards increased respiratory activity in some (A53Tα-synuclein) or all (WT and truncated forms of α-synuclein), but only in the case of strains expressing the wild type protein did this reach statistical significance for every component of respiration ( Figure 8 b–g).
(C) XPO1 high expression showed a trend of unfavorable prognostic effect on PFS in MYC -rearranged ( MYC -R + ) DLBCL.
Patients with high tumor SMARCA2 (BRM) protein expression showed a trend towards a better overall survival, although this relationship did not reach statistical significance.
Plasma levels of sCD14 showed a trend of increase in SIV+ group (10.86 ± 5.994) in comparison with NON_SIV (6.47 ± 2.54) and ART groups (8.89 ± 4.30) but did not reach significant difference (Fig. 8 B).
A comparison between gene expression fold changes and copy number variation of the differentially expressed genes (log2-fold change > ± 1) for each progeny cell line compared to HEK293 showed a trend of gained gene copies amongst the majority of genes with up-regulated mRNA levels (Supplementary Fig.
Encouragingly, SIGLEC9 expression showed a trend for an inverse correlation with MUC1-ST expression suggesting the down regulation of the receptor upon engagement (Supplementary Fig. 5d ), which was also observed at both the RNA and protein level in our in vitro studies (Supplementary Fig. 3f ).
The bone length showed a trend similar to the body weight.
showed a trend for more rapid decrease in bone pain score at one month in favor of zoledronic acid compared to oral ibandronate ( 22 ).