LSR showed a trend of positive association with KGR-F, although the correlation was not significant ( r = 0.6, p = 0.07) ( Supplementary Material 1 ).
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Although the COVID pandemic restricted the follow-up, this research conducted in a naturalistic service setting, indicated that the group receiving a combined NEAR + SCIT approach showed a trend toward improved functioning.
Likewise, PRS of LGE + segments showed a trend towards higher contractility (SMD = − 0.12; 95% CI − 0.08 to 0.31), whereas LGE− segments tended towards lower contractility (SMD = − 0.19; 95% CI = − 0.29 to − 0.08).
Furthermore, most studies showed a trend toward a shorter median survival time in the PC + LM group and the median OS reported was 29 months.
Notably, the phosphorylation level of Akt showed a trend of first rising and then falling, with a peak at 8 h at all tested extracellular vesicle concentration.
The average annual yield of the wheat-maize rotation system showed a trend of increasing and then decreasing as the manure substitution ratio increased.
The germination index of the wheat seeds treated with the base extract showed a trend of decreasing and then increasing, indicating that some toxic substances were produced by the heap during the aging process.
We also observed that, in addition to the corpus callosum, some specific white matter tracts such as the superior longitudinal tract, inferior longitudinal tract, and inferior frontal-occipital tract also showed a trend of decreased FA and increased MD, AD, and RD in the NDD-CKD and DD-CKD groups, and the extent of lesions was also more pronounced in the DD-CKD group.
The SOD activity, POD activity, proline content, and SP of ‘Yu Hong’ leaves showed a trend of increasing and then decreasing with the extension of treatment time, MDA content was gradually increasing, and the REC showed a trend of increasing and then stabilizing under heat stress.
18 showed a trend that higher PEWS during transport were associated with PICU transfers, although not statistically significant.
The HSP90 mRNA expression level showed a trend of first increasing and then decreasing with increasing intermittent cold stimulation time, the differences between the groups were significant, and the expression level in the CS6 group was significantly higher than that in the CS0 group ( P < 0.05).
Vascular oxidative stress (as determined by fluorescence of oxidized dihydroethidium products) was increased by the single exposures and showed a trend of additive augmentation in the PM + noise exposed mice ( Fig. 3 C).
In contrast, a CONCAVE shape showed a trend towards fewer recession (14.3%) at 12 months.
The LSKs of female KO mice showed a trend of reduction in γ‐H2AX levels 24 h after IR compared with those of female WT mice (Figure S5A–B ), and the significantly shorter tail moment of the LSK cells of female KO mice was clearly observed at only 1 h but not 24 h after irradiation (Figure S5C–D ).
Remarkably, miR-455-5p expression and PD-L1 tumor proportion score showed a trend of inverse correlation also in primary NSCLC from two other independent cohorts of patients (the CSS and CIMA-CUN cohorts; Additional file 21 : Table S5; Fig. 6 D, E).
After adjusting for TS VNTR, which interacts functionally with ENOSF1 rs2612091, the G/G genotype was nominally associated with inferior OS, while the 3R/3R genotype showed a trend toward inferior OS.
However, our metaanalysis only showed a trend of decreasing risk of ST, but this reduction was not significant due to the low incidence of events.
However, the mechanical pain thresholds of the sham group showed a trend opposite that of the other three groups, i.e., they declined to the nadir on POD 1, then gradually increased and approached the baseline values from PODs 3 to 7, which was similar to the behavior test results described above.
CD105 (endoglin) and TLR4 ( Li et al., 1999 ) showed a trend toward increased expression 24 hr after the fourth LPS injection ( Figure 1D ), but mean fluorescence intensities (MFIs) did not reach statistical significance.
The encapsulation efficiency (EE) of APS-LNCs showed a trend of increasing and then decreasing with the initial concentration of lignin.
Fitting showed constant coordination number (3) and distance (1.8 Å) but the Debye–Waller factor showed a trend where the ZrO 2 sample with the highest IO 3 − loading (in DI water) showed also the highest degree of disorder ( σ 2 = 0.0027 ± 0.0007) and the sample with the lower loading had decreasing disorder with rising SO 4 2− concentration (1 mM: 0.0022 ± 0.0005; 10 mM 0.0015 ± 0.0006).
Compared with the preoperative period, the RMT of the median nerve on both the paralysed and non-paralysed sides showed a trend of first increase and then gradual decrease from 2 to 12 weeks after the surgery, but still did not reach a statistical difference.
Moreover, in the crude and multivariable analysis, some factors showed a trend to association with a higher risk of mortality: previous diagnosis of IPF, older age (over 60 years), history of arterial hypertension or diabetes mellitus, impaired baseline lung function (FVC ≤ 80%, DLCO ≤ 40%) and the use of LTOT.
Globally, their results were consistent and showed a trend of a greater effect in the IMT group compared to the control/sham group.
The trial by Chen et al., 2015 [ 34 ] showed a trend toward improved PFS was observed, but the addition of cetuximab did not significantly improve the ORR of GEMOX chemotherapy in advanced BTC, and KRAS mutations did not affect the trend in ORR and PFS differences between C-GEMOX and GEMOX.