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“showed a trend”

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showed a trendP =0.061.2× alpha
Finally, the stratified analysis according to the stage of melanoma revealed that PDE5i use was associated with a significantly increased risk for in situ melanoma (two studies, 16 , 20 adjusted RR =1.31, 95% CI =1.01–1.69, P =0.04, I 2 =69%; Figure 4B ), showed a trend toward increased risk for localized melanoma (three studies, 16 , 20 adjusted RR =1.13, 95% CI =0.99–1.29, P =0.06, I 2 =23%; Figure 4B ), and showed a trend toward reduced risk for nonlocalized melanoma (three studies, 16 , 20 adjusted RR =0.79, 95% CI =0.62–1.01, P =0.06, I 2 =0%; Figure 4B ).
showed a trendp=0.061.2× alpha
Spontaneous inhibitory postsynaptic current (sIPSC) frequency recorded on M/T cells showed a trend toward increase after implicit learning (p=0.06, Kruskal-Wallis Anova followed by FDR-corrected permutation test, Enriched, n = 50 and Non-Enriched, n = 48) (for detailed statistics see Table 1 ), ( Figure 1H and Figure 1—source data 1 ) with no change in amplitude ( Table 1 , Enriched n = 48 and Non-Enriched, n = 46).
showed a trendp = 0.061.2× alpha
The distribution of bleeding sites showed a trend toward a difference between groups ( p = 0.06, Supplementary Table S5 )—gastrointestinal bleeding was more frequent in the NOAC group (55.3% vs. 30.0%), whereas transfusion-requiring events occurred more often in the APT group (40.0% vs. 10.5%).
showed a trendp = 0.061.2× alpha
coli challenge significantly ( p < 0.05) downregulated ZO-1 mRNA expression and showed a trend toward downregulating Occludin ( p = 0.06) and Claudin-1 ( p = 0.07) mRNA expression levels in the jejunum.
showed a trendP = 0.061.2× alpha
Only the presence of SST disease at baseline (HR 1.74, 95% CI 1.18-2.58, adjusted P = 0.05) was borderline significantly associated with PFS, whereas an increase in the number of brain lesions showed a trend of association that did not achieve statistical significance (HR 1.18, 95% CI 1.05-1.33, adjusted P = 0.06) ( Supplementary Table S10 , available at https://doi.org/10.1016/j.iotech.2025.101078 ).