Logrank testing showed a trend towards worse DSS based on expression of GOBP regulation of cAMP ( P = 0.07, Fig. 3 C) and significantly worse DSS based on expression of KEGG cAMP mediated signaling ( P = 0.05, Fig. 3 D) and IPA’s Cardiac β-adrenergic signaling ( P = 0.04, Fig. 3 E).
However, in MOLM-14 cells, shPSMD3 showed a trend for reduced NF-κB transcriptional activity, which was not further reduced by quizartinib therapy ( Figure 4 B; p = 0.07).
AF70 treated with apigenin also showed a trend to lower production of AFB 1 ( p -value = 0.07; Figure 2 and Figure S1, Document S1 ).
After multiple corrections, the post hoc test showed a trend for an increased R2 area at all interstimulus intervals (R2: 3–5 s: t (24) = 2.1; p = 0.07; 8–10 s: t (24) = 2.2; p = 0.06; 15–17 s: t (24) = 2.3; p = 0.05).
One multicenter study of 875 HCV-HCC recipients showed no association between DAA and HCC recurrence, while another study with 171 HCV-HCC recipients showed a trend of decreased HCC recurrence in patients receiving DAAs (hazard ratio, 0.38; P =0.07) [ 59 , 60 ].
Compared to patients on MT, those undergoing CA showed a trend towards a reduction in the composite endpoint (RR 0.59; (95% CI: 0.33–1.05); p = 0.07; I 2 = 17%) ( Figure 6 c) and a significative reduction in HF hospitalizations (RR 0.57; (95% CI: 0.41–0.78); p = 0.0006; I 2 = 0%) and AF recurrence (RR 0.35; (95% CI: 0.22–0.55); p < 0.00001; I 2 = 82%).
The change (delta) in post- versus pre-VR future self-similarity between abstainers and those relapsing showed a trend-level difference (1.6 ± 2.0 and − 0.7 ± 0.6, respectively), t (18) = 1.93, p = 0.070, but did not reach significance.
Similarly, Prevotella copri showed a trend decrease on CHOICE but increase on CONV (p=0.07).
Patterns of Fitbit-Measured MVPA Participants in the full intervention arm significantly increased average minutes of MVPA from preintervention to across the 12-week intervention period (13.95 minutes/week to 27.89 minutes/week; P <.001) and participants in the light intervention arm showed a trend for increased average minutes of MVPA from preintervention to across the 12 weeks (14.64 minutes/week to 18.35 minutes/week; P =.07; Table 2 ).
Patients who received PPIs plus antibiotics showed a trend toward shorter PFS (HR 1.65, 95% CI 0.97–2.80, P = .07; Log-rank test P = .06; median, 75 days versus 209 days) and OS (HR 1.62, 95% CI 0.84–3.11, P = .15; Log-rank test P = .15; median, 211 days versus NR) compared with patients who received only PPIs ( Supplementary Figure S4 ).
The mean Manders M2 coefficient was calculated for each subject, and Student’s t -test showed a trend ( T = −2.18, P = 0.07) towards increased overlap of GSK3β signal with nuclear staining in Control versus Alzheimer’s disease ( Fig. 4C ), providing likely validation of the mass spectrometry results.
Sex concordance between patient and provider showed a trend toward impacting the rates of electrophysiology referrals (HR, 1.18 [95% CI, 0.99–1.42]; P =0.07) but not of ICD implantations (HR, 1.12 [95% CI, 0.91–1.37]; P =0.27).
IL6 increased ( p < 0.05) in females (12.1-fold change) and showed a trend ( p = 0.07) for an increase in males (19.6-fold change; Figure 6C ).
NRF2 mRNA levels showed a trend toward decreasing in response to high glutamine ( P = 0.07) and increased after BPTES treatment, while GPX1 showed an opposite pattern ( Fig. 5 H and Supplementary Fig. 3 H ).
Notably, serum cholesterol levels showed a trend of decreasing in response to losartan ( p = 0.07) and mirabegron ( p = 0.08) compared to the DOXO-only group ( Table 2 ).
The 5 × 4 mixed-model ANCOVA still showed a trend to statistically significant time*group interaction ( p = 0.07) and time*sex interaction ( p = 0.08), with no effect of nVAS ( p = 0.835), the amount of LTRs ( p = 0.61), or group*sex interaction ( p = 0.77) for changes in PPT.
The results showed a trend of reduction in the BMI z-score in the AVG group, whereas the BMI z-score among the control group was essentially unchanged ( P =.07).
Although not statistically significant, BPH showed a trend as a risk factor for relapse (OR, 2.9; 95% CI, 0.9 to 9.5; P = 0.07).
Blood Analyses In Experiment II, compared to sows in the control group, sows that received 1,25-(OH) 2 D 3 showed a trend of higher serum calcium levels ( p = 0.07) ( Table 9 ).
The inclusion of phytogenic in the current diets did not affect the serological concentrations of cytokine TNF-α but showed a trend in the major acute-phase protein Pig-MAP to decrease at day 4 PI with T4 ( p = 0.07).
In contrast, Kalachand et al., 2020 revealed that patients with BRCA1 /2-mutated tumors showed a trend toward improved DFS as compared to those with BRCA1 /2-intact tumors (median survival: 17 vs. 6 months [HR, 0.48;95% CI, 0.22–1.06; P=0.07] and 20 vs. 11 months [HR, 0.53;95% CI, 0.26–1.09; P=0.08], respectively).
Our analysis showed a trend for association for radiomic phenotype with EGFR T790M mutation ( p = 0.07), which is in line with prior studies 20 , 32 , although not specific to EGFR T790M.
Compared with control treated mice, the anti-CD20/B220 Ab-treated 3×TgAD showed a trend toward increased activity in the OFA ( p = 0.07, 30 min, n = 5, Supplementary Fig. 5B ).
Post hoc analysis showed a trend towards a lower salivary NO 2 − , but not salivary NO 3 −, concentration, in samples received after 3 or more days compared with 2 or 1 days ( p = 0.07 and p = 0.08, respectively). 3.6.
Due to the small patient number in the KMT2C ‐MUT subgroup, the study only showed a trend toward a higher rate of DCB relative to the KMT2C ‐WT subgroup (48% vs. 28%, respectively; p = 0.07) (Figure 2J ).