In contrast, potassium calcium-activated channel subfamily M alpha 1 ( KCNMA1 ), another gene associated with EDHF-mediated responses, showed a trend toward increased expression in GDM HUVECs compared to NG, both under basal conditions ( p = 0.1195) and after insulin stimulation ( p = 0.0548) ( Figure 6 F), indicating a possible compensatory upregulation of the EDHF pathway in GDM. 3.
2.7% of placebo (HR 0.61, 95% CI 0.38-0.99, P = 0.04), while nonfatal MI showed a trend toward reduction (2.9% vs. 3.9%, HR 0.74, 95% CI 0.51-1.08, P = 0.12).
Meta-regression showed a trend toward lower CBT efficacy for positive symptoms with a higher SZA disorder proportion (β = +0.10 SMD per 10% increase in AP; p = 0.12), though it was not statistically significant.
combination therapy) showed a trend toward improved outcomes after combination therapy (HR: 0.21, 95% CI: 0.03–1.50, p=0.12), but that did not reach statistical significance.
Correlation between EME and RT ( Figure 2 ) showed no strong association except for the 2 and 8 h time points postfeeding, although the 8 h time point showed a trend ( P = 0.12) in LR cows.
Results showed a trend of higher STMN1 expression in poor responders compared to good responders ( p = 0.12) in the ITT population (Fig. 1 A).
This study showed a trend toward an increase in cerebral palsy in those exposed to multiple courses (2.9%, n = 6 vs. 0.5%, n = 1; P = 0.12).
Similarly, there was no difference in survival between female and male smokers using Kaplan-Meier survival analysis although females showed a trend towards higher long-term mortality ( P = 0.12; Fig. 4 B).
The IS1 group showed a trend of decreased overall survival possibilities ( p = 0.12), and a larger sample size is needed to determine whether immunotypes could serve as a robust prognostic indicator for PRCC.
The current density of p.I1498M showed a 59% reduction, whereas the other variants did not show statistically significant modifications (although p.R1636Q showed a trend towards reduction, P = 0.12).
Accordingly, in the present study, VO 2peak values showed a trend to be lower in those with LV-GLS below the median (17.5 ± 1.0 vs 19.9 ± 1.0 mL/min/kg, p = 0.12).
In the 3 liver lesions that we isolated, VIM transcripts were significantly up-regulated ( P < 0.05 ), ZEB1 and ZEB2 transcript levels showed a trend to increase ( P < 0.12 and P < 0.25, respectively) (Fig. 3i ).
Only the treated male mice showed a trend ( p = 0.12) to improved performance as indicated by an increase in spontaneous alteration rate.
A similar analysis for GAS6 showed a trend towards shorter survival in patients with high GAS6 expression (Figure S3c, p = 0.12).
Demographic Relationships Univariate testing showed that high wave amplitudes were more likely in females ( p < 0.001), for low body weights (linear regression, r = −0.46, p < 0.001) and when the blood Hb was low at baseline ( r = −0.48, p < 0.001), but they only showed a trend to decrease with age ( p = 0.12).
PFS was similar in both treatment arms, whereas OS showed a trend in favor of the panitumumab-containing arm (hazard ratio for death, 0.67; 95% CI, 0.41 to 1.11; p = 0.12).
This effect was not observed with high-dose vaccine, where Pfs25 showed a trend to lower antibody levels after coadministration of the 2 vaccines ( Figure 2G compared with Figure 2B, P = 0.12), and there was no effect of vaccine combinations on anti-Pfs230 responses ( Figure 2, H and I ).
The inclusion of center-based cluster effects showed a trend towards ( P =0.12) improved model fit compared with fitting the same model using ordinary logistic regression with no clustering.
Scintillation counts showed a trend for increased 3 H-glucose signal in IRβ-expressing cells (Student’s t -test; p = 0.120), which exhibited ∼30% more uptake than control cells ( Figure 1E ).
Although survival differences among infiltration groups did not reach statistical significance, T-cell infiltrated patients showed a trend toward improved outcomes ( online supplemental figure 2B ; HR=0.31, p=0.12).
11 However, a prospective, phase II, B-F1RST study only showed a trend toward a PFS benefit (hazard ratio (HR) = 0.66; 90% confidence interval (CI): 0.42–1.02; P = .12) and an OS benefit (HR = 0.77; 90% CI: 0.41–1.43; P = .48). 12 Cancer is a genetic disease, and multiple genetic mutations may lead to resistance to therapy, including immunotherapy. 13 Recent studies r
In patients with newly diagnosed T2D ( Supplementary Table 7 ), the p.Trp325Trp carriers showed a trend (p = 0.12) towards enhanced β-cell sensitivity to glucose during the OGTT ( Extended Data Fig. 3c ).
After propensity‐score adjustment, PF‐AES showed a trend toward a lower rate of MACCE and a favorable rate of TLF as compared to PP‐ZES (HR 0.70; 95%CI 0.45 to 1.10, P = 0.12; and HR 0.88; 95%CI 0.47 to 1.65, P = 0.68, respectively).
However, subjects with combined obesity and UDP showed a trend toward lower exercise efficiency (p=0.12). 3.4.
However, consistent with our observations after a single injury, SOCS3 MscKO muscles contained a higher proportion of fibers with a single central nucleus after two sequential injuries ( Fig 4I ; ** P < 0.01) compared to muscles from control mice which showed a trend towards a higher proportion of fibers with more than two centralised nuclei ( Fig 4I ; P = 0.12).